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Kok, P. (author), Dijkstra, J. (author), Botha, C.P. (author), Post, F.H. (author), Kaijzel, E. (author), Que, I. (author), Löwik, C.W.G.M. (author), Reiber, J.H.C. (author), Lelieveldt, B.P.F. (author)This paper explores new methods to visualize and fuse multi-2D bioluminescence imaging (BLI) data with structural imaging modalities such as micro CT and MR. A geometric, back-projection-based 3D reconstruction for superficial lesions from multi-2D BLI data is presented, enabling a coarse estimate of the 3D source envelopes from the multi-2D BLI...conference paper 2007
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Kok, P. (author), Baiker, M. (author), Hendriks, E.A. (author), Post, F.H. (author), Dijkstra, J. (author), Löwik, C.W.G.M. (author), Lelieveldt, B.P.F. (author), Botha, C.P. (author)The analysis of multi-timepoint whole-body small animal CT data is greatly complicated by the varying posture of the subject at different timepoints. Due to these variations, correctly relating and comparing corresponding regions of interest is challenging. In addition, occlusion may prevent effective visualization of these regions of interest....journal article 2010
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Diba, M. (author), Löwik, D.W.P.M. (author), Van Hest, J.C.M. (author), Jansen, J.A. (author), Leeuwenburgh, S.C.G. (author)Noncovalent bonds are often reversible and sensitive to external stimuli. Although noncovalent interactions are inherently weak and generally perceived as inadequate to construct macroscopic materials of sufficient integrity and cohesion, the emergence of nanotechnology has shown that the intrinsic weakness of noncovalent interactions can be...conference paper 2013
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Dzyubachyk, O. (author), Khmelinskii, A. (author), Plenge, E. (author), Kok, P. (author), Snoeks, T.J. (author), Poot, D.H. (author), Löwik, C.W. (author), Botha, C.P. (author), Niessen, W.J. (author), Van der Weerd, L. (author), Meijering, E. (author), Lelieveldt, B.P.F. (author)In small animal imaging studies, when the locations of the micro-structures of interest are unknown a priori, there is a simultaneous need for full-body coverage and high resolution. In MRI, additional requirements to image contrast and acquisition time will often make it impossible to acquire such images directly. Recently, a resolution...journal article 2014
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Boonstra, M.C. (author), Van Driel, P.B.A.A. (author), Van Willigen, D.M. (author), Stammes, M.A. (author), Prevoo, H.A.J.M. (author), Tummers, Q.R.J.G. (author), Mazar, A.P. (author), Beekman, F.J. (author), Kuppen, P.J.K. (author), Van de Velde, C.J.H. (author), Löwik, C.W.G.M. (author), Frangioni, J.V. (author), Van Leeuwen, F.W.B. (author), Sier, C.F.M. (author), Vahrmeijer, A.L. (author)Pre- and intraoperative diagnostic techniques facilitating tumor staging are of paramount importance in colorectal cancer surgery. The urokinase receptor (uPAR) plays an important role in the development of cancer, tumor invasion, angiogenesis, and metastasis and over-expression is found in the majority of carcinomas. This study aims to develop...journal article 2015