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Kim, Eugene (author), Barth, R. (author), Dekker, C. (author)SMC (structural maintenance of chromosomes) protein complexes are an evolutionarily conserved family of motor proteins that hold sister chromatids together and fold genomes throughout the cell cycle by DNA loop extrusion. These complexes play a key role in a variety of functions in the packaging and regulation of chromosomes, and they have...review 2023
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Ploetz, Evelyn (author), Ambrose, Benjamin (author), Barth, A. (author), Börner, Richard (author), Kapanidis, Achillefs N. (author), Lohman, Timothy M. (author), Steffen, Fabio D. (author), Cordes, Thorben (author), Magennis, Steven W. (author), Lerner, Eitan (author)PIFE was first used as an acronym for protein-induced fluorescence enhancement, which refers to the increase in fluorescence observed upon the interaction of a fluorophore, such as a cyanine, with a protein. This fluorescence enhancement is due to changes in the rate ofcis/transphotoisomerisation. It is clear now that this mechanism is...review 2023
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Lerner, Eitan (author), Barth, A. (author), Hendrix, Jelle (author), Ambrose, Benjamin (author), Birkedal, Victoria (author), Blanchard, Scott C. (author), Börner, Richard (author), Joo, C. (author), Lee, Tae Hee (author)Single-molecule FRET (smFRET) has become a mainstream technique for studying biomolecular structural dynamics. The rapid and wide adoption of smFRET experiments by an ever- increasing number of groups has generated significant progress in sample preparation, measurement procedures, data analysis, algorithms and documentation. Several labs...review 2021
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Navigating the crowd: visualizing coordination between genome dynamics, structure, and transcriptionShaban, Haitham A. (author), Barth, R. (author), Bystricky, Kerstin (author)The eukaryotic genome is hierarchically structured yet highly dynamic. Regulating transcription in this environment demands a high level of coordination to permit many proteins to interact with chromatin fiber at appropriate sites in a timely manner. We describe how recent advances in quantitative imaging techniques overcome caveats of...review 2020
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Watson, S.J. (author), Moro, Alberto (author), Reis, Vera (author), Baniotopoulos, Charalampos (author), Barth, Stephan (author), Bartoli, Gianni (author), Bauer, Florian (author), Jamieson, Peter (author), Schmehl, R. (author)This paper represents an expert view from Europe of future emerging technologies within the wind energy sector considering their potential, challenges, applications and technology readiness and how they might evolve in the coming years. These technologies were identified as originating primarily from the academic sector, some start-up...review 2019