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Resilience and resistance to the accumulation of amyloid plaques and neurofibrillary tangles in centenarians: An age-continuous perspective

Zhang, M. (author), Ganz, Andrea B. (author), Rohde, Susan (author), Rozemuller, Annemieke J.M. (author), Bank, Netherlands Brain (author), Reinders, M.J.T. (author), Scheltens, Philip (author), Hulsman, M. (author), Hoozemans, Jeroen J.M. (author), Holstege, H. (author)

Introduction: With increasing age, neuropathological substrates associated with Alzheimer's disease (AD) accumulate in brains of cognitively healthy individuals—are they resilient, or resistant to AD-associated neuropathologies?. Methods: In 85 centenarian brains, we correlated NIA (amyloid) stages, Braak (neurofibrillary tangle) stages, and...

journal article 2022

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Evolutionary Dynamics of Treatment-Induced Resistance in Cancer Informs Understanding of Rapid Evolution in Natural Systems

Pressley, Mariyah (author), Salvioli, Monica (author), Lewis, David B. (author), Richards, Christina L. (author), Brown, Joel S. (author), Staňková, K. (author)

Rapid evolution is ubiquitous in nature. We briefly review some of this quite broadly, particularly in the context of response to anthropogenic disturbances. Nowhere is this more evident, replicated and accessible to study than in cancer. Curiously cancer has been late - relative to fisheries, antibiotic resistance, pest management and...

journal article 2021

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A Chip Integrity Monitor for Evaluating Moisture/Ion Ingress in mm-Sized Single-Chip Implants

Akgün, O.C. (author), Nanbakhsh, K. (author), Giagka, Vasiliki (author), Serdijn, W.A. (author)

For mm-sized implants incorporating silicon integrated circuits, ensuring lifetime operation of the chip within the corrosive environment of the body still remains a critical challenge. For the chip's packaging, various polymeric and thin ceramic coatings have been reported, demonstrating high biocompatibility and barrier properties. Yet, for...

journal article 2020

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Influence of Bow-Wave Breaking on the Added Resistance of Fast Ships

Choi, BongJun (author)

doctoral thesis 2018

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The influence of shallow water and hull form variations on inland ship resistance

Rotteveel, E. (author), Hekkenberg, R.G. (author)

Effects of a hull form variation and shallow water on a 110-meter inland ship are presented as preliminary results of the Top Ships project, which is initiated in order to improve inland ship design tools and design guidelines.

conference paper 2015

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Overtopping on Grass Covered Dikes: Resistance and Failure of the Inner Slopes

Trung, L.H. (author)

A large part of the Vietnamese population is living close to the coast. The sea is an essential source for supporting lives. Coastal flooding, on the other hand, threatens the people, land and infrastructures every year. Some hundreds years ago, the first sea dikes were built in Thai Binh and Nam Dinh provinces. In the north, the coastline is...

doctoral thesis 2014

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Numerical analysis of added resistance on ships in short waves

Seo, Min-Guk (author), Yang, Kyung-Kyu (author), Park, Dong-Min (author), Kim, Yonghwan (author)

journal article 2014

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Behaviour of high strength steel moment joints

Girão Coelho, A.M. (author), Bijlaard, F.S.K. (author)

The design of joints to European standard EN 1993 within the semi-continuous/partially restrained philosophy is restricted to steel grades up to S460. With the recent development of high performance steels, the need for these restrictions should be revisited. The semicontinuous joint modelling can be adopted as long as the joint develops...

journal article 2010

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Effects of heavy metals on microbial diversity and bacterial resistance in marine sediments

Toes, A.C.M. (author)

In North-Western Europe alone more than 200 million cubic meters of contaminated sludge is dredged on an annual basis. Deposition of dredged harbour sediments in relatively undisturbed ecosystems is often considered a viable option, under the assumption that metals are not released into the environment. This research initially focused on the...

doctoral thesis 2008

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Social and material appropriation of neighborhood space: Collective space and resistance in a Dutch urban community

De Haan, H. (author)

Workshop 3. Session 3.1: Privacy and public life

conference paper 2005

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Aspects of the cavitating propeller tip vortex as a source of inboard noise and vibration

van Wijngaarden, Erik (author), Bosschers, Johan (author), Kuiper, Gert (author)

journal article 2005

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Effect van meeneming van de dynamische waterlijnlengte, door trim en inzinking, in de 'Residuary Hull Resistance' gebaseerd op de 'Delft Systematic Yacht Hull Series'

Visch, Guido (author)

master thesis 2003

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Model tests with the Schooner Athena. Attached: Comparison of DSYSH polynomes with the Athena Results

Vermeulen, K.J (author)

report 2002

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Thin films of the charge-density-wave oxide Rb(0.30) MoO(3) by pulsed-laser deposition

Mantel, O.C. (author), Van der Zant, H.S.J. (author), Steinfort, A.J. (author), Dekker, C. (author), Traeholt, C. (author), Zandbergen, H.W. (author)

journal article 1997

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Thin-film growth of the charge-density-wave oxide Rb0.30MoO3

Van der Zant, H.S.J. (author), Mantel, O.C. (author), Dekker, C. (author), Mooij, J.E. (author), Traeholt, C. (author)

journal article 1996

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Proceedings of the 19th WEGEMT School Numerical Simulation of Hydrodynamics: Ships and Offshore Structures, Part 1: Propeller & Lifting surfaces, Marine propellers, from design to production, Ecole Centrale Nantes, France

conference paper 1993

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Estimation of resistance, trim and draft of planing craft

Nagai, Tamotsu (author), Yoshida, Yasushi (author)

journal article 1993

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Low-frequency noise in quantum point contacts

Liefrink, F. (author), Scholten, A.J. (author), Dekker, C. (author), Dijkhuis, J.I. (author), Eppenga, R. (author), Van Houten, H. (author), Foxon, C.T. (author)

conference paper 1992

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Low-frequency noise of quantum point contacts in the ballistic and quantum Hall regime

Liefrink, F. (author), Scholten, A.J. (author), Dekker, C. (author), Eppenga, R. (author), Van Houten, H. (author), Foxon, C.T. (author)

journal article 1991

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Spontaneous resistance switching and low-frequency noise in quantum point contacts

Dekker, C. (author), Scholten, A.J. (author), Liefrink, F. (author), Eppenga, R. (author), Van Houten, H. (author), Foxon, C.T. (author)

journal article 1991