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de Vor, Lisanne (author), van Dijk, Bruce (author), van Kessel, Kok (author), Kavanaugh, Jeffrey S. (author), de Haas, Carla (author), Aerts, Piet C. (author), Ramakers, R.M. (author), Beekman, F.J. (author), Weinans, Harrie (author)
Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach to improve the diagnosis and potential treatment of biofilm-related infections. Here, we show...
journal article 2022
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van Dijk, Bruce (author), Hooning van Duyvenbode, J. Fred F. (author), de Vor, Lisanne (author), Nurmohamed, F. Ruben H.A. (author), Lam, Marnix G.E.H. (author), Poot, Alex J. (author), Ramakers, R.M. (author), Koustoulidou, Sofia (author), Beekman, F.J. (author), Weinans, Harrie (author)
Implant infections caused by Staphylococcus aureus are difficult to treat due to biofilm formation, which complicates surgical and antibiotic treatment. We introduce an alternative approach using monoclonal antibodies (mAbs) targeting S. aureus and provide evidence of the specificity and biodistribution of S.-aureus-targeting antibodies in a...
journal article 2023