Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer: a consensus recommendation from the EORTC Imaging and Breast Cancer Groups

Breast cancer remains the most common cause of cancer death among women. Despite its considerable histological and molecular heterogeneity, those characteristics are not distinguished in most definitions of oligometastatic disease and clinical trials of oligometastatic breast cancer. After an exhaustive review of the literature covering all...

Diffusion of chlorides in cracked strain-hardening cement-based composites (SHCC)

Strain-hardening cement-based composites (SHCC) are high-performance fiber-reinforced composites with promising durability properties due to their considerably enhanced crack control under tensile load conditions. The knowledge of the transport properties of such composites in cracked state are crucial for estimating their durability...

Solid-phase crystallization of ultra high growth rate amorphous silicon films

In this paper, we report on the deposition of amorphous silicon (a-Si:H) films at ultra-high growth rate (11–60?nm/s) by means of the expanding thermal plasma technique, followed by solid-phase crystallization (SPC). Large-grain (?1.5??m) polycrystalline silicon was obtained after SPC of high growth rate (?25?nm/s) deposited a-Si:H films. The...

Integrating physical and human management systems for effective water resources management

Integrated water resources management (IWRM) is regarded as an essential framework for the sustainable management of water resources. A key challenge in implementing IWRM involves coordinating the decisions between diverse actors with potentially conflicting interests. It is argued that the attainment of sustainable water management outcomes in...

Diminishing Chat Confusion by Multiple Visualizations

In this article, we address the problem of confusion and co-text-loss in chat communication, identify requirements for a solution, discuss related work and present a new approach for addressing co-text loss in text-based chats. We report about first experiences with our solution and give an outlook on future work directions. The core idea of our...

Air entrainment kechanisms from artificial supercavities: insight based on numerical simulations

An examination of thermal modeling affects on the numerical prediction of large-scale cavitating fluid flows

Solution of machinery problems by field investigation