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van Oossanen, R. (author), Maier, A. (author), Godart, Jérémy (author), Pignol, Jean Philippe (author), Denkova, A.G. (author), van Rhoon, Gerard C. (author), Djanashvili, K. (author)Objective: To investigate the potential of hybrid Pd/Fe-oxide magnetic nanoparticles designed for thermo-brachytherapy of breast cancer, considering their specific loss power (SLP) and clinical constraints in the applied magnetic field. Methods: Hybrid nanoparticles consisting of palladium-core and iron oxide shell of increasing thickness,...journal article 2024
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Androulakis, Ioannis (author), Ferrero, Riccardo (author), van Oossanen, R. (author), Manzin, Alessandra (author), Denkova, A.G. (author), Djanashvili, K. (author), Nadar, R.A. (author), van Rhoon, G.C. (author)While hyperthermia has been shown to induce a variety of cytotoxic and sensitizing effects on cancer tissues, the thermal dose–effect relationship is still not well quantified, and it is still unclear how it can be optimally combined with other treatment modalities. Additionally, it is speculated that different methods of applying...journal article 2023
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van Oossanen, R. (author), Godart, Jeremy (author), Brown, J.M.C. (author), Maier, A. (author), Pignol, Jean-Philippe (author), Denkova, A.G. (author), Djanashvili, K. (author), van Rhoon, G.C. (author)Background: Treatment of early-stage breast cancer currently includes surgical removal of the tumor and (partial) breast irradiation of the tumor site performed at fractionated dose. Although highly effective, this treatment is exhaustive for both patient and clinic. In this study, the theoretical potential of an alternative treatment combining...journal article 2022
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Maier, A. (author), van Oossanen, R. (author), van Rhoon, G.C. (author), Pignol, J.P.M. (author), Dugulan, A.I. (author), Denkova, A.G. (author), Djanashvili, K. (author)Heterostructured magnetic nanoparticles show great potential for numerous applications in biomedicine due to their ability to express multiple functionalities in a single structure. Magnetic properties are generally determined by the morphological characteristics of nanoparticles, such as the size/shape, and composition of the nanocrystals....journal article 2022
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