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Brown, Michael D. (author), Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), Koekkoek, Sebastiaan K.E. (author), Strydis, C. (author), Bosch, Johannes G. (author), Arvanitis, Petros (author), Springeling, Geert (author), Leus, G.J.T. (author), De Zeeuw, Chris I. (author), Kruizinga, P. (author)Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), an imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction...journal article 2024
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Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), Bosman, Laurens W.J. (author), De Zeeuw, Chris I. (author), Koekkoek, Sebastiaan K.E. (author), Kruizinga, P. (author)Functional ultrasound (fUS) using a 1-D-array transducer normally is insufficient to capture volumetric functional activity due to being restricted to imaging a single brain slice at a time. Typically, for volumetric fUS, functional recordings are repeated many times as the transducer is moved to a new location after each recording, resulting...journal article 2023
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Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), De Zeeuw, Chris I. (author), Koekkoek, Sebastiaan K.E. (author), Kruizinga, P. (author)Volumetric 3-D Doppler ultrasound imaging can be used to investigate large scale blood dynamics outside of the limited view that conventional 2-D power Doppler images (PDIs) provide. To create 3-D PDIs, 2-D-matrix array transducers can be used to insonify a large volume for every transmission; however, these matrices suffer from low...journal article 2023
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Bauer, Staf (author), van Wingerden, Nathalie (author), Jacobs, Thomas (author), van der Horst, Annabel (author), Zhai, Peipei (author), Betting, Jan Harm L.F. (author), Strydis, C. (author), White, Joshua J. (author), De Zeeuw, Chris I. (author), Romano, Vincenzo (author)Neural activity exhibits oscillations, bursts, and resonance, enhancing responsiveness at preferential frequencies. For example, theta-frequency bursting and resonance in granule cells facilitate synaptic transmission and plasticity mechanisms at the input stage of the cerebellar cortex. However, whether theta-frequency bursting of Purkinje...journal article 2022
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Siddiqi, M.A. (author), Beurskens, Robert H.S.H. (author), Kruizinga, Pieter (author), De Zeeuw, Chris I. (author), Strydis, C. (author)Modern Implantable Medical Devices (IMDs) are vulnerable to security attacks because of their wireless connectivity to the outside world. One of the main security challenges is establishing trust between the IMD and an external reader/programmer in order to facilitate secure communication. Numerous device-pairing schemes have been proposed to...journal article 2021
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Betting, J.L.F. (author), Romano, Vincenzo (author), Al-Ars, Z. (author), Bosman, L.W.J. (author), Strydis, C. (author), De Zeeuw, Chris I. (author)Rodents engage in active touch using their facial whiskers: they explore their environment by making rapid back-and-forth movements. The fast nature of whisker movements, during which whiskers often cross each other, makes it notoriously difficult to track individual whiskers of the intact whisker field. We present here a novel algorithm,...journal article 2020
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de Groot, Andres (author), van den Boom, Bastijn Jg (author), van Genderen, Romano M. (author), Coppens, Joris (author), van Veldhuijzen, John (author), Bos, Joop (author), Hoedemaker, Hugo (author), Negrello, M.J.F. (author), Willuhn, Ingo (author), De Zeeuw, Chris I. (author), Hoogland, Tycho M. (author)Miniaturized fluorescence microscopes (miniscopes) have been instrumental to monitor neural signals during unrestrained behavior and their open-source versions have made them affordable. Often, the footprint and weight of open-source miniscopes is sacrificed for added functionality. Here, we present NINscope: a light-weight miniscope with a...journal article 2020
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Zhang, Yichuan (author), Venkateswaran, Seshasailam (author), Higuera, Gustavo A. (author), Nath, Suvra (author), Shpak, Guy (author), Matray, Jeffrey (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author), Kushner, Steven A. (author), Bradley, Mark (author), De Zeeuw, Chris I. (author)Substrates for neuron culture and implantation are required to be both biocompatible and display surface compositions that support cell attachment, growth, differentiation, and neural activity. Laminin, a naturally occurring extracellular matrix protein is the most widely used substrate for neuron culture and fulfills some of these...journal article 2020
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Koekkoek, S. K.E. (author), Soloukeytbalvandany, S. (author), Generowicz, B.S. (author), Vanhoogstraten, W. S. (author), Deoude, N. L. (author), Boele, H. J. (author), Strydis, C. (author), Leus, G.J.T. (author), De Zeeuw, C. I. (author)Functional ultrasound (fUS) is a relatively new imaging modality to study the brain with a high spatiotemporal resolution and a wide field-of-view. In fUS detailed images of cerebral blood flow and volume are used to derive functional information, as changes in local flow and/or volume may reflect neuronal activation through neurovascular...conference paper 2018
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Smaragdos, Georgios (author), Chatzikonstantis, Georgios (author), Kukreja, Rahul (author), Sidiropoulos, Harry (author), Rodopoulos, Dimitrios (author), Sourdis, Ioannis (author), Al-Ars, Z. (author), Kachris, Christoforos (author), Soudris, Dimitrios (author), De Zeeuw, Chris I. (author), Strydis, C. (author)Objective. The advent of high-performance computing (HPC) in recent years has led to its increasing use in brain studies through computational models. The scale and complexity of such models are constantly increasing, leading to challenging computational requirements. Even though modern HPC platforms can often deal with such challenges, the...journal article 2017
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De Zeeuw, W.C.T.F. (author)In de stedelijke corridor zit volgens de Nederlandse overheid de economische groeipotentie van Europa. Weliswaar vindt een concentratie van economische dynamiek en werkgelegenheid plaats in stedelijke agglomeraties, maar het idee van een economische ‘ruggengraat’ van Europa is een mythe, stelt Friso de Zeeuw.journal article 2015
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De Zeeuw, W.C.T.F. (author), Drost, R. (author)De grote steden in ons land groeien vooral door immigratie en de aanleg van nieuwe wijken binnen de stadsgrenzen. De modieuze stelling dat yuppen met bakfietsen in de binnenstad de groei veroorzaken en de stad aantrekkelijk maken, vertekent de werkelijkheid.journal article 2015
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- De Zeeuw, W.C.T.F. (author) journal article 2015
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Kros, L. (author), Eelkman Rooda, O.H.J. (author), Spanke, J.K. (author), Alva, P. (author), Van Dongen, M.N. (author), Karapatis, A. (author), Tolner, E.A. (author), Strydis, C. (author), Davey, N. (author), Winkelman, B.H.J. (author), Negrello, M. (author), Serdijn, W.A. (author), Steuber, V. (author), Van den Maagdenberg, A.M.J.M. (author), De Zeeuw, C.I. (author), Hoebeek, F.E. (author)Objective Disrupting thalamocortical activity patterns has proven to be a promising approach to stop generalized spike-and-wave discharges (GSWDs) characteristic of absence seizures. Here, we investigated to what extent modulation of neuronal firing in cerebellar nuclei (CN), which are anatomically in an advantageous position to disrupt cortical...journal article 2015
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Germann, M. (author), Kaufmann, J. (author), Lemmen, C.H.J. (author), Van Oosterom, P.J.M. (author), De Zeeuw, K. (author)Both the conceptual schema language INTERLIS and the land administration domain model (LADM) share the same model driven architecture (MDA) principles. In this paper we explore how INTERLIS and LADM complement each other in actual implementation of land administration system based on the LADM using INTERLIS tools. In Switzerland, the requirement...conference paper 2015
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- De Zeeuw, W.C.T.F. (author) journal article 2015
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Van Dongen, M.N. (author), Hoebeek, F.E. (author), Koekkoek, S.K.E. (author), De Zeeuw, C.I. (author), Serdijn, W.A. (author)This paper investigates the efficacy of high frequency switched-mode neural stimulation. Instead of using a constant stimulation amplitude, the stimulus is switched on and off repeatedly with a high frequency (up to 100 kHz) duty cycled signal. By means of tissue modeling that includes the dynamic properties of both the tissue material as well...journal article 2015
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De Zeeuw, W.C.T.F. (author)In het Kamerdebat over het Energieakkoord van 13 januari jl. diende D66-Kamerlid Stientje van Veldhoven een motie in om bij windenergieprojecten voortaan een externe gebiedscoördinator aan te stellen. Die gaat zich bezighouden met het werven van draagvlak in de omgeving, mogelijkheden tot participatie onderzoeken en eventueel bemiddelen bij ...journal article 2015
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De Zeeuw, W.C.T.F. (author), Kersten, R.A.E.M. (author), Van der Hee, M. (author), Konings, B. (author), Fokkema, J. (author), Schepman, M.H.L. (author), Zandvliet, N. (author)Een handreiking voor marktpartijen en overheden in het verlengde van de Reiswijzer Gebiedsontwikkeling 2011. Neprom en Akro Consult met medewerking van de Praktijkleerstoel Gebiedsontwikkeling, TU Delft.report 2014
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De Zeeuw, W.C.T.F. (author)De nationale sturing op ruimtelijke investeringen neemt af door bezuinigingen en decentralisatie. De focus van het Rijk ligt steeds meer op het versterken van de al lopende ruimtelijk-economische ontwikkelingen. Doordat ook investeringsmogelijkheden van corporaties en gemeenten verminderen, worden ruimtelijke investeringen steeds...journal article 2014