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Kirchner, K. (author), Schwab, Christoph (author)
We formulate standard and multilevel Monte Carlo methods for the kth moment M<sub>ε</sub><sup>k</sup>[ξ] of a Banach space valued random variable ξ:Ω→E, interpreted as an element of the k-fold injective tensor product space ⊗<sub>ε</sub><sup>k</sup>E. For the standard Monte Carlo estimator of M<sub>ε</sub><sup>k</sup>[ξ], we prove the k...
journal article 2024
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Ninan, Dr Johan (author), Hertogh, M.J.C.M. (author), Lim, Y. (author), de Boer, J.J. (author), Pesamaa, Ossi (author), Van Acker, Maarten (author), Schwab, Eva (author), Ilsbroekx, Raf (author), Bernsteiner, Johannes (author)
conference paper 2023
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Zhou, Liangbin (author), Xu, J. (author), Schwab, Andrea (author), Tong, Wenxue (author), Zheng, Lizhen (author), Li, Zhuo (author), Xu, Shunxiang (author), van Osch, G.J.V.M. (author), Wen, Chunyi (author), Qin, Ling (author)
As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...
review 2023
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Schwab, Andrea (author), Wesdorp, Marinus A. (author), Xu, J. (author), Abinzano, Florencia (author), Loebel, Claudia (author), Levato, Riccardo (author), Eglin, David (author), Narcisi, Roberto (author), Malda, Jos (author), van Osch, G.J.V.M. (author)
Background: The use of acellular hydrogels to repair osteochondral defects requires cells to first invade the biomaterial and then to deposit extracellular matrix for tissue regeneration. Due to the diverse physicochemical properties of engineered hydrogels, the specific properties that allow or even improve the behaviour of cells are not yet...
journal article 2023
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de Jong, P.H. (author), Schwab, A.L. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)
Shape-morphing structures have the ability to adapt to various target shapes, offering significant advantages for many applications. However, predicting their behavior presents challenges. Here, we present a method to assess the shape-matching behavior of shape-morphing structures using a multibody systems approach wherein the structure is...
journal article 2023
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Wesdorp, Marinus A. (author), Schwab, Andrea (author), Bektas, Ezgi Irem (author), Narcisi, Roberto (author), Eglin, David (author), Stoddart, Martin J. (author), van Osch, G.J.V.M. (author), D'Este, Matteo (author)
Neutrophils play a pivotal role in orchestrating the immune system response to biomaterials, the onset and resolution of chronic inflammation, and macrophage polarization. However, the neutrophil response to biomaterials and the consequent impact on tissue engineering approaches is still scarcely understood. Here, we report an in vitro...
journal article 2023
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Oosterhoff, J.H.F. (author), Dijkstra, H.F. (author), Karhade, Aditya V. (author), Poolman, Rudolf W. (author), Schipper, Inger B. (author), Nelissen, R.G.H.H. (author), van Embden, Daphne (author), Jaarsma, Ruurd L. (author), Schwab, Joseph H. (author)
Purpose: Effects of clockwise torque rotation onto proximal femoral fracture fixation have been subject of ongoing debate: fixated right-sided trochanteric fractures seem more rotationally stable than left-sided fractures in the biomechanical setting, but this theoretical advantage has not been demonstrated in the clinical setting to date. The...
journal article 2023
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Oosterhoff, J.H.F. (author), Karhade, Aditya V. (author), Groot, Olivier Q. (author), Schwab, Joseph H. (author), Heng, Marilyn (author), Klang, Eyal (author), Prat, Dan (author)
Purpose: Mortality prediction in elderly femoral neck fracture patients is valuable in treatment decision-making. A previously developed and internally validated clinical prediction model shows promise in identifying patients at risk of 90-day and 2-year mortality. Validation in an independent cohort is required to assess the generalizability;...
journal article 2023
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Haasnoot, Jelle (author), Happee, R. (author), van der Wijk, V. (author), Schwab, A.L. (author)
Bicycle simulators have been the subject of considerable research, however, few of these attempts have integrated direct balance control and realistic freedom of motion to deliver a real-world dynamic cycling experience. This study presents the BIKE (Bicycle Intrinsic Kinematics Emulator) system, a kinematic bicycle simulator, developed with...
journal article 2023
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Dialynas, G. (author), Christoforidis, Christos (author), Happee, R. (author), Schwab, A.L. (author)
Experiments and human rider models were used to investigate bicycle balance and steering using visuo/vestibular motion and proprioceptive feedback taking into account sensory delays. An instrumented steer-by-wire bicycle designed and built at the TU Delft bicycle laboratory was used to investigate rider responses with and with reduced...
journal article 2022
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Reijne, M.M. (author), Dehkordi, Sepehr G. (author), Glaser, Sebastien (author), Twisk, D (author), Schwab, A.L. (author)
Falls are responsible for a large proportion of serious injuries and deaths among cyclists [1-4]. A common fall scenario is loss of balance during an emergency braking maneuver to avoid another vehicle [5-7]. Automated Vehicles (AV) have the potential to prevent these critical scenarios between bicycle and cars. However, current Threat...
conference paper 2022
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Schwab, A.L. (author), Meijaard, J.P. (author)
journal article 2021
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Bruni, S. (author), Meijaard, J.P. (author), Rill, G. (author), Schwab, A.L. (author)
A review of the current use of multibody dynamics methods in the analysis of the dynamics of vehicles is given. Railway vehicle dynamics as well as road vehicle dynamics are considered, where for the latter the dynamics of cars and trucks and the dynamics of single-track vehicles, in particular motorcycles and bicycles, are reviewed....
journal article 2020
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Lee, O.Z.A. (author), Rasch, Alexander (author), Schwab, A.L. (author), Dozza, Marco (author)
This paper introduces a framework for modelling the cyclist's comfort zone. Unlike the driver's comfort zone, little is known about the cyclist's. The framework draws on existing literature in cognitive science about driver behaviour to explain experimental results from cycling field trials, and the modelling of these results. We modelled...
journal article 2020
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Dialynas, G. (author), de Haan, Jelle (author), Schouten, A.C. (author), Happee, R. (author), Schwab, A.L. (author)
The objective of this study was to identify the dynamic response of the bicycle rider’s body during translational perturbations, in an effort to improve two-wheeler safety and comfort. A bicycle mock-up was equipped with sensors measuring three-dimensional seat and trunk accelerations and rider’s force responses at the seat, handlebars, and...
journal article 2020
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Dialynas, G. (author), Happee, R. (author), Schwab, A.L. (author)
With the resurgence in bicycle ridership in the last decade and the continuous increase of electric bicycles in the streets a better understanding of bicycle rider behaviour is imperative to improve bicycle safety. Unfortunately, these studies are dangerous for the rider, given that the bicycle is a laterally unstable vehicle and most of the...
journal article 2019
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Schwab, A.L. (author), Dialynas, G. (author), Happee, R. (author)
The bicycle, being unstable at low speed and marginally stable at high speed, is sensitive to lateral perturbations. One of the major lateral perturbations is crosswind, which can lead to accidents and fatalities. Here we investigate the effect of crosswind on the lateral dynamics and control of the bicycle in a wide range of forward speeds and...
conference paper 2018
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Reijne, M.M. (author), Bregman, D.J.J. (author), Schwab, A.L. (author)
Descend technique and performance vary among elite racing cyclists and it is not clear what slower riders should do to improve their performance. An observation study was performed of the descending technique of members of a World Tour cycling team and the technique of each member was compared with the fastest descender amongst them. The...
conference paper 2018
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Dialynas, G. (author), Happee, R. (author), Schwab, A.L. (author)
Since the 1800s, the design of bicycles involves a mechanical linkage between the handlebar and the fork assembly. Herein, we propose an innovation, where the traditional mechanical connection between the handlebar and fork is decoupled and replaced with sensors, servomo-tors and a microcontroller allowing artificial manipulation of the bicycle...
conference paper 2018
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Baines, P.M. (author), Schwab, A.L. (author), van Soest, A.J. (author)
Metabolic energy expenditure during human gait is poorly understood. Mechanical energy loss during heel strike contributes to this energy expenditure. Previous work has estimated the energy absorption during heel strike as 0.8 J using an effective foot mass model. The aim of our study is to investigate the possibility of determining the energy...
journal article 2018
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