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Ruf, M.T. (author), IJspeert, M. (author), van Dam, S.B. (author), de Jong, N. (author), van den Berg, J.H. (author), Hanson, R. (author)
Diamond membrane devices containing optically coherent nitrogen-vacancy (NV) centers are key to enable novel cryogenic experiments such as optical ground-state cooling of hybrid spin-mechanical systems and efficient entanglement distribution in quantum networks. Here, we report on the fabrication of a (3.4 ± 0.2) μm thin, smooth (surface...
journal article 2019
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Cioni, Bianca (author), Nevedomskaya, Ekaterina (author), Melis, Monique H.M. (author), van Burgsteden, Johan (author), Stelloo, Suzan (author), Hodel, Emma (author), Spinozzi, Daniele (author), de Jong, Jeroen (author), Wessels, L.F.A. (author), More Authors (author)
Fibroblasts are abundantly present in the prostate tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) which play a key role in cancer development. Androgen receptor (AR) signaling is the main driver of prostate cancer (PCa) progression, and stromal cells in the TME also express AR. High-grade tumor and poor clinical...
journal article 2018
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Bracco Garcia, M.P. (author), Torrelo Villa, G. (author), Noordam, Sander (author), de Jong, Glenn (author), Hanefeld, U. (author)
The hydroxynitrile lyase from Prunus amygdalus was immobilized on Celite R-633. The immobilized enzyme could successfully be utilized in buffer saturated MTBE and excellent conversions of benzaldehyde to R-mandelonitrile were observed. No leaching occurred. To achieve high enantioselectivities, the suppression of the undesired background...
journal article 2018
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Voorneveld, J.D. (author), Engelhard, S. (author), Vos, H.J. (author), Reijnen, M. (author), Gijsen, F.J.H. (author), Versluis, M. (author), Jebbink, Erik Groot (author), de Jong, N. (author), Bosch, J. G. (author)
Treatment of abdominal aortic (AA) aneurysms and stenotic lesions may be improved by analyzing their associated blood flow patterns. Angle-independent blood flow patterns in the AA can be obtained by combining echo-particle image velocimetry (ePIV) with high frame rate contrast-enhanced ultrasonography. However, ePIV performance is affected...
journal article 2018
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Lajoinie, Guillaume (author), Luan, Ying (author), Gelderblom, Erik (author), Dollet, Benjamin (author), Mastik, Frits (author), Dewitte, Heleen (author), Lentacker, Ine (author), de Jong, N. (author), Versluis, Michel (author)
journal article 2018
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de Jong, M.A. (author), Hysi, Pirro (author), Spector, Tim (author), Niessen, W.J. (author), Koudstaal, M.J. (author), Wolvius, Eppo B. (author), Kayser, Manfred (author), Böhringer, Stefan (author)
Landmarking of 3D facial surface scans is an important analysis step in medical and biological applications, such as genome-wide association studies (GWAS). Manual landmarking is often employed with considerable cost and rater dependent variability. Landmarking automatically with minimal training is therefore desirable. We apply statistical...
journal article 2018
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Çelik, M. (author), Paulussen, Geert (author), van Erp, Dennis (author), de Jong, W. (author), Boersma, B.J. (author)
Rotating wickless and stationary capillary cylindrical heat pipes are widely used heat transfer devices. Transient behavior of such heat pipes has been investigated numerically with computational fluid dynamics and lumped parameter models. In this paper, the advantages of both methods are combined into a novel engineering model that is low in...
journal article 2018
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Faturrochman, Gerry Julian (author), de Jong, M.M. (author), Santbergen, R. (author), Folkerts, W. (author), Zeman, M. (author), Smets, A.H.M. (author)
In this work we consider noise barriers with integrated photovoltaic modules. The novelty is that bifacial modules are considered. A full scale bifacial photovoltaic noise barrier was built and its power output was monitored. In addition we developed an advanced numerical model for predicting this power output for given weather conditions....
journal article 2018
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Beekers, D.I. (author), van Rooij, Tom (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)
Ultrasound contrast agents consist of gas-filled coated microbubbles that oscillate upon ultrasound insonification. Their characteristic oscillatory response provides contrast enhancement for imaging and has the potential to locally enhance drug delivery. Since microbubble response depends on the local acoustic pressure, an ultrasound...
journal article 2018
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Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)
Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...
journal article 2018
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Skachkov, Ilya (author), Luan, Ying (author), Van Tiel, Sandra T. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bernsen, Monique R. (author), Kooiman, Klazina (author)
In vivo cell tracking of therapeutic, tumor, and endothelial cells is an emerging field and a promising technique for imaging cardiovascular disease and cancer development. Site-specific labeling of endothelial cells with the MRI contrast agent superparamagnetic iron oxide (SPIO) in the absence of toxic agents is challenging. Therefore, the...
journal article 2018
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Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Noothout, E.C. (author), Chang, Z.Y. (author), Tan, M. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents a front-end application-specified integrated circuit (ASIC) integrated with a 2-D PZT matrix transducer that enables in-probe digitization with acceptable power dissipation for the next-generation endoscopic and catheter-based 3-D ultrasound imaging systems. To achieve power-efficient massively parallel analog-to-digital...
journal article 2018
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Komor, Malgorzata A. (author), Bosch, Linda J.W. (author), Bounova, Gergana (author), Bolijn, Anne S. (author), Delis‐van Diemen, Pien M. (author), Rausch, Christian (author), Hoogstrate, Youri (author), Stubbs, Andrew P. (author), de Jong, Mark (author), Wessels, L.F.A. (author), More Authors (author)
Consensus molecular subtyping is an RNA expression-based classification system for colorectal cancer (CRC). Genomic alterations accumulate during CRC pathogenesis, including the premalignant adenoma stage, leading to changes in RNA expression. Only a minority of adenomas progress to malignancies, a transition that is associated with specific...
journal article 2018
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Khalilnezhad, H. (author), Popov, M. (author), van der Sluis, L. (author), Bos, Jorrit A. (author), de Jong, Jan P.W. (author), Ametani, A. (author)
Zero-missing is a phenomenon in shunt compensated cable systems in which the current through the line breaker does not cross the zero point for several cycles. This paper deals with a thorough investigation on countermeasures of the zero-missing phenomenon in transmission systems and determines the requirements, benefits, and risks of...
journal article 2018
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de Jong, T.L. (author), Klink, Camiel (author), Moelker, Adriaan (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)
Introduction: Accurate needle placement is crucial in image-guided needle interventions. A targeting error may be introduced due to undesired needle deflection upon insertion through tissue, caused by e.g. patient breathing, tissue heterogeneity, or asymmetric needle tip geometries. This paper aims to quantify needle deflection in thermal...
conference paper 2018
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de Jong, T.L. (author), van de Berg, N.J.P. (author), Tas, L. (author), Moelker, Adriaan (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)
Purpose: Accurate and precise needle placement is of utmost importance in interventional radiology. However, targeting can be challenging due to, eg, tissue motion and deformation. Steerable needles are a possible solution to overcome these challenges. The present work studied the clinical need for steerable needles. We aimed to answer three...
journal article 2018
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Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)
Typically, ultrasonic flow meters assume linear wave propagation. Nevertheless, if the transducers of an ultrasonic flow sensor excite a pressure wave with a high amplitude, nonlinear wave propagation effects become significant. The appearance of higher harmonics increases the bandwidth of the received signal, which may potentially lead to a...
conference paper 2018
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Kuperus, J.S. (author), Smit, E.J.M. (author), Pouran, B. (author), van Hamersvelt, R.W. (author), van Stralen, Marijn (author), Seevinck, PR (author), Buckens, C.F. (author), Bleys, Ronald L.A.W. (author), Weinans, H.H. (author), Oner, F. C. (author), de Jong, P.A. (author), Verlaan, J-J (author)
Diffuse idiopathic skeletal hyperostosis (DISH) is often theorized to be an ossification of the anterior longitudinal ligament (ALL). Using computed tomography (CT) imaging and cryomacrotome sectioning, we investigated the spatial relationship between the ALL and newly formed bone in DISH to test this hypothesis. In the current study, four...
journal article 2018
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Gilvari, H. (author), Eijssen, Dirk (author), IJzermans, Kasper (author), Stolk, Maarten (author), Homsma, Thom (author), de Jong, W. (author), Schott, D.L. (author)
The large-scale storage of biomass pellets is challenging due to health issues, material loss, and the risk of fire and explosions. The thermal conductivity is a material property which plays a key role in determining the self-heating properties of biomass. Meanwhile, understanding the thermal conductivity and the affecting factors help to...
poster 2018
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Fool, F. (author), de Wit, J. (author), Vos, H.J. (author), Bera, D. (author), de Jong, N. (author), Verweij, M.D. (author)
The huge amount of data that needs to be transferred between probe and imaging system becomes a major issue when the data transfer capacity is limited, e.g. in handheld systems, wireless probes and miniaturized probes. The amount of data can be significantly reduced by using two-stage beamforming. The first stage consists of a fixed focus...
conference paper 2018
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