- document
-
Gorter de Vries, A.R. (author), de Groot, P.A. (author), van den Broek, M.A. (author), Daran, J.G. (author)Background: The ease of use of CRISPR-Cas9 reprogramming, its high efficacy, and its multiplexing capabilities have brought this technology at the forefront of genome editing techniques. Saccharomyces pastorianus is an aneuploid interspecific hybrid of Saccharomyces cerevisiae and Saccharomyces eubayanus that has been domesticated for...journal article 2017
- document
-
Pasma, J.H. (author), van Kordelaar, J. (author), de Kam, D. (author), Weerdesteyn, V. (author), Schouten, A.C. (author), van der Kooij, H. (author)Background: Closed loop system identification (CLSIT) is a method to disentangle the contribution of underlying systems in standing balance. We investigated whether taking into account lower leg muscle activation in CLSIT could improve the reliability and accuracy of estimated parameters identifying the underlying systems. Methods: Standing...journal article 2017
- document
-
Laan, A.C. (author), Denkova, A.G. (author)This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying,...journal article 2017
- document
-
Kenjeres, S. (author), Tjin, J.L. (author)In the present study, we investigate the concept of the targeted delivery of pharmaceutical drug aerosols in an anatomically realistic geometry of the human upper and central respiratory system. The geometry considered extends from the mouth inlet to the eighth generation of the bronchial bifurcations and is identical to the phantom model...journal article 2017
- document
-
Vogt, Mark (author), van Gerwen, D.J. (author), Lubbers, Wouter (author), van den Dobbelsteen, J.J. (author), Hagenaars, Martin (author)Background and Objectives Neuraxial blockade using a midline approach can be challenging. Part of this challenge lies in finding the optimal approach of the needle to its target. The present study aimed at finding (1) the optimal point of insertion of the needle between the tips of 2 adjacent spinous processes and (2) the optimal angle...journal article 2017
- document
-
Sajadi, B. (author), Alijani, F. (author), Goosen, J.F.L. (author), van Keulen, A. (author)Characterization of nonlinear behavior of micro-mechanical components in MEMS applications plays an important role in their design process. In this paper, nonlinear dynamics, stability and pull-in mechanisms of an electrically actuated circular micro-plate subjected to a differential pressure are studied. For this purpose, a reduced-order...journal article 2017
- document
-
Adal, K.M. (author), Van Etten, Peter G. (author), Martinez, Jose P (author), Rouwen, Kenneth W. (author), Vermeer, K.A. (author), van Vliet, L.J. (author)People with diabetes mellitus need annual screening to check for the development of diabetic retinopathy. Tracking small retinal changes due to early diabetic retinopathy lesions in longitudinal fundus image sets is challenging due to intra- and inter-visit variability in illumination and image quality, the required high registration accuracy...journal article 2017
- document
-
Hoekstra, M. (author), de Weerd, F.A. (author), Kleerebezem, R. (author), van Loosdrecht, Mark C.M. (author)The implementation of autotrophic nitrogen removal in the mainstream of a municipal wastewater treatment plant is currently pursued. Among the crucial unknown factors are the kinetic properties of anaerobic ammonium oxidising (anammox) bacteria at low temperatures. In this study we investigated the adaptation of a fast-growing anammox culture...journal article 2017
- document
-
Turşucu, S. (author), Spandaw, J.G. (author), Flipse, S.M. (author), de Vries, M.J. (author)Students in senior pre-university education encounter difficulties in the application of mathematics into physics. This paper presents the outcome of an explorative qualitative study of teachers’ beliefs about improving the transfer of algebraic skills from mathematics into physics. We interviewed 10 mathematics and 10 physics teachers using...journal article 2017
- document
-
Qian, Kun (author), Tang, Linkai (author), Wagemaker, M. (author), He, Yan Bing (author), Liu, Dongqing (author), Li, Hai (author), Shi, Ruiying (author), Li, Baohua (author), Kang, Feiyu (author)Through a facile sodium sulfide (Na<sub>2</sub>S)-assisted hydrothermal treatment, clean and nondefective surfaces are constructed on micrometer-sized Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub> particles. The remarkable improvement of surface quality shows a higher first cycle Coulombic efficiency (≈95%), a significantly enhanced cycling...journal article 2017
- document
-
Grillo Peternella, F. (author), Ouyang, B. (author), Horsten, R.C. (author), Haverdings, Michael (author), Kat, Pim (author), Caro-Schuurman, J. (author)We experimentally demonstrate an interrogation procedure of a ring-resonator ultrasound sensor using a fiber Mach-Zehnder interferometer (MZI). The sensor comprises a silicon ring resonator (RR) located on a silicon-oxide membrane, designed to have its lowest vibrational mode in the MHz range, which is the range of intravascular ultrasound (IVUS...journal article 2017
- document
-
van de Ruit, M.L. (author), Grey, Michael J. (author)Both motor imagery and mirror training have been used in motor rehabilitation settings to promote skill learning and plasticity. As motor imagery and mirror training are suggested to be closely linked, it was hypothesized that mirror training augmented by motor imagery would increase corticospinal excitability (CSE) significantly compared to...journal article 2017
- document
-
Simbula, A. (author), Schatzl, M. (author), Alpeggiani, F. (author), Andreani, L.C. (author), Schäffler, F. (author), Fromherz, T. (author), Galli, M. (author), Gerace, D. (author)We report on the realization of high-Q/V photonic crystal cavities in thin silicon membranes, with resonances around 1.55 μm wavelength. The cavity designs are based on a recently proposed photonic crystal implementation of the Aubry-André-Harper bichromatic potential, defined from the superposition of two one-dimensional lattices with a non...journal article 2017
- document
-
Strauch, M. (author), Shao, Y. (author), Bociort, F. (author), Urbach, Paul (author)The increased usage of liquid lenses motivates us to investigate surface waves on the liquid's surface. During fast focal switching, the surface waves decrease the imaging quality. We propose a model that describes the surface modes appearing on a liquid lens and predicts the resonance frequencies. The effects of those surface modes on a...journal article 2017
- document
-
Kartakis, Sokratis (author), Fu, A. (author), Mazo, M. (author), McCann, Julie A. (author)Energy constraint long-range wireless sensor/actuator-based solutions are theoretically the perfect choice to support the next generation of city-scale cyber-physical systems. Traditional systems adopt periodic control which increases network congestion and actuations while burdens the energy consumption. Recent control theory studies...journal article 2017
- document
-
Ragesh Kumar, T. P. (author), Hari, S. (author), Damodaran, Krishna K. (author), Ingólfsson, Oddur (author), Hagen, C.W. (author)We present first experiments on electron beam induced deposition of silacyclohexane (SCH) and dichlorosilacyclohexane (DCSCH) under a focused high-energy electron beam (FEBID). We compare the deposition dynamics observed when growing pillars of high aspect ratio from these compounds and we compare the proximity effect observed for these...journal article 2017
- document
- Hänsel, A. (author), Reyes Reyes, A. (author), Persijn, ST (author), Urbach, Paul (author), Bhattacharya, N. (author) journal article 2017
- document
-
Vaibhav, V.K. (author)This paper considers the non-Hermitian Zakharov-Shabat (ZS) scattering problem which forms the basis for defining the SU(2) nonlinear Fourier transformation (NFT). The theoretical underpinnings of this generalization of the conventional Fourier transformation are quite well established in the Ablowitz-Kaup-Newell-Segur formalism; however,...journal article 2017
- document
-
Horeman, T. (author), Kment, Christoph (author), Kerkhoffs, Gino M.M.J. (author), Tuijthof, G.J.M. (author)The goal of this study was to determine the preferred handle design for two degrees of freedom steerable arthroscopic cutter by performing a two-step development approach. The expected usefulness and usability of control components of three entirely different handles were defined by an on-line survey with 101 students and the actual control...journal article 2017
- document
-
Speth, Daan R. (author), Lagkouvardos, Ilias (author), Wang, Yong (author), Qian, Pei Yuan (author), Dutilh, Bas E. (author), Jetten, M.S.M. (author)Several recent studies have indicated that members of the phylum Planctomycetes are abundantly present at the brine-seawater interface (BSI) above multiple brine pools in the Red Sea. Planctomycetes include bacteria capable of anaerobic ammonium oxidation (anammox). Here, we investigated the possibility of anammox at BSI sites using...journal article 2017