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Boelhouwer, P.J. (author), van der Heijden, H.M.H. (author)The Netherlands is not known for the occurrence of earthquakes. This is, however, a hot topic in the province of Groningen. Because of gas extraction, this area suffered from more than 1000 earthquakes. Most of them are not very intensive, but also bigger earthquakes of between 2 and 3 on the scale of Richter have been measured. In the last...journal article 2018
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van der Heijden, R.A.J. (author), Poot, D.H.J. (author), Ekinci, Melek (author), Kotek, Gyula (author), van Veldhoven, Peter L.J. (author), Klein, S. (author), Verhaar, Jan A.N. (author), Krestin, Gabriel P. (author), Bierma-Zeinstra, Sita M.A. (author), van Middelkoop, Marienke (author), Oei, Edwin H.G. (author)Background: Altered perfusion might play an important role in the pathophysiology of patellofemoral pain (PFP), a common knee complaint with unclear pathophysiology. Purpose: To investigate differences in dynamic contrast-enhanced (DCE)-MRI perfusion parameters between patients with PFP and healthy control subjects. Population/Subjects...journal article 2018
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Hooimeijer, F.L. (author), van der Heijden, Wouter (author)Doel van dit project is inzicht te krijgen in de ruimtelijke consequenties van de energietransitie en de klimaatadaptatie voor de onder- en bovengrondse ordening van het Leiden Bio Science Park (LBSP). Het LBSP is een belangrijke economische motor voor Leiden en de Leidse regio. Het park behoort tot de top vijf in Europa op gebied van Life...report 2018
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van der Heijden, T.J.T. (author), Abraham, E. (author)Among the barriers for renewable energy penetration (SDG 7 and SDG 13) are lack of large scale storage and irregularity and unpredictability of supply. Ties van der Heijden and Edo Abraham have a vision on how water infrastructure in the Dutch delta can contribute to the energy transition with model-based optimisation and ‘demand response...journal article 2019
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Vossen, David M. (author), Verhagen, Caroline V.M. (author), van der Heijden, Martijn (author), Essers, Paul B.M. (author), Bartelink, Harry (author), Verheij, Marcel (author), Wessels, L.F.A. (author), van den Brekel, Michiel W.M. (author), Vens, Conchita (author)About half of advanced stage head and neck squamous cell carcinoma (HNSCC) patients can be cured by chemoradiotherapy. Patient outcome may be partially determined by the genetic alterations in HNSCC, rendering these alterations promising candidate prognostic factors and/or therapeutic targets. However, their relevance in patient outcome...journal article 2019
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Hagenbeek, Fiona A. (author), Bomer, N. (author), van Hilten, J. A. (author), Fu, J. (author), van der Heijden, A. A.W.A. (author), van der Spek, A. (author), Boersma, E. (author), van den Akker, E.B. (author), Reinders, M.J.T. (author)Metabolomics examines the small molecules involved in cellular metabolism. Approximately 50% of total phenotypic differences in metabolite levels is due to genetic variance, but heritability estimates differ across metabolite classes. We perform a review of all genome-wide association and (exome-) sequencing studies published between November...journal article 2019
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Souaid, C. (author), van der Heijden, H.M.H. (author), Elsinga, M.G. (author)Despite efforts to promote and accelerate the adoption of innovative, affordable, and zero-energy dwelling solutions, the number of dwellings complying with standards such as the EPBD remains relatively low as we reach year 2020. Studies have already explored potential challenges and opportunities to the uptake of such designs. However,...journal article 2020
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Klarenbeek, Sjoerd (author), Doornebal, Chris W. (author), Kas, Sjors M. (author), Bonzanni, Nicola (author), Bhin, Jinhyuk (author), Braumuller, Tanya M. (author), van der Heijden, Ingrid (author), de Bruijn, Roebi (author), Wessels, L.F.A. (author)Effective treatment of invasive lobular carcinoma (ILC) of the breast is hampered by late detection, invasive growth, distant metastasis, and poor response to chemotherapy. Phosphoinositide 3-kinase (PI3K) signaling, one of the major druggable oncogenic signaling networks, is frequently activated in ILC. We investigated treatment response and...journal article 2020
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van der Vos, K.E. (author), Vis, D.J. (author), Nevedomskaya, E. (author), Kim, Y. (author), Choi, W. (author), McConkey, D. (author), Wessels, L.F.A. (author), van Rhijn, B.W.G. (author), Zwart, W. (author), van der Heijden, M.S. (author)Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease that often recurs despite aggressive treatment with neoadjuvant chemotherapy and (radical) cystectomy. Basal and luminal molecular subtypes have been identified that are linked to clinical characteristics and have differential sensitivities to chemotherapy. While it has been...journal article 2020
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Luo, D. (author), van der Heijden, H.M.H. (author), Boelhouwer, P.J. (author)The management of the public rental sector has undergone tremendous change worldwide. Especially in China, given the large supply of public rental housing (PRH) in the short term, the management of PRH (PRHM) has been faced with a series of problems. The existing PRHM is unsustainable and a new scheme has been proposed. In this study we analyze...journal article 2020
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Ibis, F. (author), Dhand, P. (author), Suleymanli, S. (author), van der Heijden, A.E.D.M. (author), Kramer, H.J.M. (author), Eral, H.B. (author)Accurate Calcium Oxalate Monohydrate (COM) solubility measurements are essential for elucidating the physiochemical mechanism behind the formation of kidney stones, nephrolithiasis. Yet the reported solubility values of COM in ultrapure water, arguably the simplest solvent relevant for nephrolithiasis, vary significantly depending on implemented...journal article 2020
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Meurs, Henk (author), Sharmeen, F. (author), Marchau, V.A.W.J. (author), van der Heijden, Rob (author)Mobility as a Service (MaaS) involves integration of various forms of public and private transport services into a single mobility service, accessible on demand. For MaaS to become successful, different suppliers of transport services have to cooperate in alliances in order to bring new benefits in the short and long term. Past experience...journal article 2020
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- Boelhouwer, P.J. (author), van der Heijden, H.M.H. (author) report 2020
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van der Heijden, D.S. (author), Ledergerber, Anton (author), Gill, Rajan (author), D'Andrea, Raffaello (author)An iterative bias estimation framework is presented that mitigates position-dependent ranging errors often present in ultra-wideband localization systems. State estimation and control are integrated, such that the positioning accuracy improves over iterations. The framework is experimentally evaluated on a quadcopter platform, resulting in...journal article 2021
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Elsinga, M.G. (author), van der Heijden, H.M.H. (author), Donoso-gomez, R.E. (author)This chapter evaluates the Dutch social housing model and its impact on the quality of neighbourhoods. It describes the theoretical debate on the link between affordable housing and planning and the different models for social rental housing. The chapter looks at the changing link between social housing and urban renewal and how social housing...book chapter 2021
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Plettenburg, S. G.J. (author), Hoppe, T. (author), van der Heijden, H.M.H. (author), Elsinga, M.G. (author)In 2015 the Housing Act was revised in order to further regulate the social housing sector in the Netherlands and thereby improve the steering possibilities for the central government to coordinate housing associations. This included local performance agreements for social housing policy obtaining a legal status. By introducing this policy...journal article 2021
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Souaid, C. (author), van der Heijden, H.M.H. (author), Elsinga, M.G. (author)After more than ten years since the introduction of Near Zero-Energy Buildings (NZEBs), the transition towards a zero-energy new built environment can still be considered slow despite European Member States’ various efforts to facilitate, promote and accelerate their implementation and uptake. The barriers to sustainability measures in general...journal article 2021
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Residential satisfaction of private tenants in China's superstar cities: The case of Shenzhen, ChinaLi, B. (author), Jin, C. (author), Jansen, S.J.T. (author), van der Heijden, H.M.H. (author), Boelhouwer, P.J. (author)In recent years, Chinese housing policies have been shifting from encouraging homeownership toward developing the private rented sector, especially in the superstar cities. Nevertheless, what are the target groups and characteristics of private rental housing in Chinese superstar cities, and whether the private rental housing is capable of...journal article 2021
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Ibis, F. (author), Yu, Tsun Wang (author), Marques Penha, F. (author), Ganguly, Debadrita (author), Nuhu, Manzoor Alhaji (author), van der Heijden, A.E.D.M. (author), Kramer, H.J.M. (author), Eral, H.B. (author)A droplet-based microfluidic platform is presented to study the nucleation kinetics of calcium oxalate monohydrate (COM), the most common constituent of kidney stones, while carefully monitoring the pseudo-polymorphic transitions. The precipitation kinetics of COM is studied as a function of supersaturation and pH as well as in the presence...journal article 2021
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Irimia, D. (author), Jose Shirley, J. (author), Garg, Anshul S. (author), Nijland, Davey P.A. (author), van der Heijden, A.E.D.M. (author), Kramer, H.J.M. (author), Eral, H.B. (author)Nonphotochemical laser-induced nucleation (NPLIN) is a promising primary nucleation control method, yet its underlying mechanism remains elusive. To contribute to the discussion on whether the polarization of laser irradiation in NPLIN experiments influences the polymorphic outcome, we revisit NPLIN experiments with aqueous glycine solutions...journal article 2021