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Guarneri, A. (author), van Berkel, Willem JH (author), Paul, C.E. (author)Coenzymes are ubiquitous in Nature, assisting in enzyme-catalysed reactions. Several coenzymes, nicotinamides and flavins, have been known for close to a century, whereas variations of those organic molecules have more recently come to light. In general, the requirement of these coenzymes imposes certain constraints for in vitro enzyme use in...review 2019
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Li, Z. (author), Huo, Jixiang (author), Bricker, J.D. (author)Focusing on the sediment in Suyahu Reservoir (a typical plain reservoir in Henan Province, China), concentrations of eutrophication-causing substances (TOC, TN and TP) and heavy metal contamination (Zn, Pb, Cd, Cu, Cr, Ni, As and Hg) were measured. Spatial distribution of these contaminants and the resulting potential ecological risk were...review 2019
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Söder, Lennart (author), Tómasson, Egill (author), Estanqueiro, Ana (author), Flynn, Damian (author), Hodge, Bri Mathias (author), Couto, António (author), Pudjianto, Danny (author), Strbac, Goran (author), De Vries, Laurens (author)The integration of renewable energy sources, including wind power, in the adequacy assessment of electricity generation capacity becomes increasingly important as renewable energy generation increases in volume and replaces conventional power plants. The contribution of wind power to cover the electricity demand is less certain than...review 2019
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Fraaije, A. (author), Flipse, S.M. (author)The concept of Responsible Research & Innovation (RRI) seems to gain initial momentum. The lack of collective meaning however, results in a plethora of publications, which describe RRI from ad hoc perspectives. To provide a robust foundation for scholars and practitioners seeking to implement RRI, we aim to integrate those perspectives...review 2019
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Boelhouwer, P.J. (author)The Dutch housing market suffered more than many other West-European housing markets from the global financial crisis. After some stimulation measures at the beginning of the crisis, the market was hit hard by several government policies in both the rented and the owner-occupied sectors. Against this background this paper pays attention to...review 2019
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Verbeeck, N. (author), Caprioli, Richard M. (author), Van de Plas, Raf (author)Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that can map the spatial distribution of molecules with high chemical specificity. IMS does not require prior tagging of molecular targets and is able to measure a large number of ions concurrently in a single experiment. While this makes it particularly suited...review 2019
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Zhang, Hao (author), Liu, Dong E. (author), Wimmer, M.T. (author), Kouwenhoven, Leo P. (author)Majorana zero modes are localized quasiparticles that obey non-Abelian exchange statistics. Braiding Majorana zero modes forms the basis of topologically protected quantum operations which could, in principle, significantly reduce qubit decoherence and gate control errors at the device level. Therefore, searching for Majorana zero modes in...review 2019
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Musa, Musa M. (author), Hollmann, F. (author), Mutti, Francesco G. (author)Deracemisation via chemo-enzymatic or multi-enzymatic approaches is the optimum substitute for kinetic resolution, which suffers from the limitation of a theoretical maximum 50% yield albeit high enantiomeric excess is attainable. This review covers the recent progress in various deracemisation approaches applied to the synthesis of...review 2019
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Mestrom, L. (author), Przypis, Marta (author), Kowalczykiewicz, Daria (author), Pollender, André (author), Kumpf, Antje (author), Marsden, S.R. (author), Szymańska, Katarzyna (author), Hanefeld, U. (author), Hagedoorn, P.L. (author)Enzymes are nature's catalyst of choice for the highly selective and efficient coupling of carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial glycosylation reactions, since chemical synthetic routes require extensive use of laborious protection group manipulations and often lack regio- and stereoselectivity....review 2019
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Daneshpour Aryadi, H. (author), Youk, H.O. (author)Communicating is crucial for cells to coordinate their behaviors. Immunological processes, involving diverse cytokines and cell types, are ideal for developing frameworks for modeling coordinated behaviors of cells. Here, we review recent studies that combine modeling and experiments to reveal how immune systems use autocrine, paracrine, and...review 2019
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Delavari, Vahid (author), Shaban, Elahi (author), Janssen, M.F.W.H.A. (author), Hassanzadeh, Alireza (author)Purpose: A large number of systematic reviews (SRs) studies have been performed in the cloud computing field, demonstrating miscellaneous outcomes and utilizing different approaches. Accordingly, a meta-review of cloud SRs is needed to appraise the results of such studies and create an integrated understanding. The paper aims to discuss these...review 2019
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van de Wal, R. S.W. (author), Zhang, X. (author), Minobe, S. (author), Jevrejeva, S. (author), Riva, R.E.M. (author), Little, C. (author), Richter, K. (author), Palmer, M. D. (author)Many processes affect sea level near the coast. In this paper, we discuss the major uncertainties in coastal sea-level projections from a process-based perspective, at different spatial and temporal scales, and provide an outlook on how these uncertainties may be reduced. Uncertainty in centennial global sea-level rise is dominated by the ice...review 2019
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Gernat, D.C. (author), Brouwer, E. (author), Ottens, M. (author)Although present in concentrations in microgrammes per litre level, aldehydes, in particular those derived from Strecker degradation, are known to majorly contribute to the undesired wort flavour of alcohol-free beers. In order to improve currently available products, one needs to understand the underlying cause for the over-prevalence and...review 2019
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- Weninger, B. (author), Mulder, F.M. (author) review 2019
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Brous, P.A. (author), Janssen, M.F.W.H.A. (author), Herder, P.M. (author)Organizations are increasingly looking to adopt the Internet of Things (IoT) to collect the data required for data-driven decision-making. IoT might yield many benefits for asset management organizations engaged in infrastructure asset management, yet not all organizations are equipped to handle this data. IoT data is collected, stored, and...review 2019
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Swuste, P.H.J.J. (author), van Nunen, K. (author), Reniers, G.L.L.M.E. (author), Khakzad, N. (author)Major accidents in Western countries, receiving a lot of media attention in the 1970s, are starting point for research into internal and external domino effects in the chemical and petrochemical sectors and clusters. Initially, these reports are published by government institutions and government-related research centres. With the upcoming...review 2019
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Papadimitriou, E. (author), Filtness, Ashleigh (author), Theofilatos, Athanasios (author), Ziakopoulos, Apostolos (author), Quigley, Claire (author), Yannis, George (author)The objective of this paper is the review and comparative assessment of infrastructure related crash risk factors, with the explicit purpose of ranking them based on how detrimental they are towards road safety (i.e. crash risk, frequency and severity). This analysis was carried out within the SafetyCube project, which aimed to identify and...review 2019
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Maier, H. R. (author), Razavi, S. (author), Kapelan, Z. (author), Matott, L. S. (author), Kasprzyk, J. (author), Tolson, B. A. (author)Environmental models are used extensively to evaluate the effectiveness of a range of design, planning, operational, management and policy options. However, the number of options that can be evaluated manually is generally limited, making it difficult to identify the most suitable options to consider in decision-making processes. By linking...review 2019
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de Kruijff, R.M. (author)A recent addition to the treatment options in external beam therapy, so-called FLASH radiotherapy, shows remarkable healthy-tissue-sparing properties in a number of pre-clinical studies without impacting the overall treatment efficacy. Its potential in clinical applications is attracting a great deal of interest in the medical community. The...review 2019
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Milchram, C. (author), Märker, Carolin (author), Schlör, Holger (author), Kunneke, R.W. (author), van de Kaa, G. (author)The current transition towards low-carbon energy systems does not only involve changes in technologies but is also shaped by changes in the rules and regulations (i.e., the institutions) that govern energy systems. Institutional change can be influenced by changes in core values - normative principles such as affordability, security of supply...review 2019