- document
-
Winter, Levin N. (author), Buşe, Florena (author), de Graaf, Daan (author), von Gleissenthall, Klaus (author), Kulahcioglu Ozkan, Burcu (author)Byzantine fault-tolerant algorithms promise agreement on a correct value, even if a subset of processes can deviate from the algorithm arbitrarily. While these algorithms provide strong guarantees in theory, in practice, protocol bugs and implementation mistakes may still cause them to go wrong. This paper introduces ByzzFuzz, a simple yet...journal article 2023
- document
-
van Riet, T.C.T. (author), de Graaf, W.M. (author), de Lange, Jan (author), Kober, J. (author)Being one of the oldest en most frequently performed invasive procedures; the lack of scientific progress of tooth removal procedures is impressive. This has most likely to do with technical limitations in measuring different aspects of these keyhole procedures. The goal of this study is to accurately capture the full range of motions during...journal article 2023
- document
-
Neerincx, Anouk (author), Li, Y. (author), van de Sande, Kelvin (author), Broz, F. (author), Neerincx, M.A. (author), de Graaf, Maartje (author)Social robots can support children in their socio-emotional development [38]. To improve the cooperation between a child and a social robot, a good relationship is vital. Self-disclosure is an essential element for building personal relationships. Yet, knowledge about the effects of self-disclosure in child-robot interactions is still lacking....conference paper 2023
- document
-
Biemolt, J. (author), Meeus, Eva J. (author), de Zwart, Felix J. (author), de Graaf, Jeen (author), Laan, Petrus C.M. (author), de Bruin, Bas (author), Burdyny, T.E. (author), Rothenberg, Gadi (author), Yan, Ning (author)Immobilizing molecular catalysts on electrodes is vital for electrochemical applications. However, creating robust electrode-catalyst interactions while maintaining good catalytic performance and rapid electron transfer is challenging. Here, without introducing any foreign elements, we show a bottom-up synthetic approach of constructing the...journal article 2023
- document
-
Langeveld, J.G. (author), Schilperoort, Remy (author), Heijnen, Leo (author), Elsinga, Goffe (author), Schapendonk, Claudia E.M. (author), Fanoy, Ewout (author), de Schepper, Evelien I.T. (author), Koopmans, Marion P.G. (author), de Graaf, Miranda (author), Medema, G.J. (author)Over the course of the Corona Virus Disease-19 (COVID-19) pandemic in 2020–2022, monitoring of the severe acute respiratory syndrome coronavirus 2 ribonucleic acid (SARS-CoV-2 RNA) in wastewater has rapidly evolved into a supplementary surveillance instrument for public health. Short term trends (2 weeks) are used as a basis for policy and...journal article 2023
- document
-
de Graaf, Miranda (author), Langeveld, J.G. (author), Post, Johan (author), Carrizosa, Christian (author), Franz, Eelco (author), Izquierdo-Lara, Ray W. (author), Elsinga, Goffe (author), Heijnen, Leo (author), Medema, G.J. (author)Despite high vaccination rates in the Netherlands, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate. Longitudinal sewage surveillance was implemented along with the notification of cases as two parts of the surveillance pyramid to validate the use of sewage for surveillance, as an early warning tool, and to...journal article 2023
- document
-
Kasi, D.G. (author), de Graaf, M.N.S. (author), Motreuil-Ragot, P.A. (author), Frimat, Jean-Phillipe M. S. (author), Ferrari, Michel D. (author), Sarro, Pasqualina M (author), Mastrangeli, Massimo (author), van den Maagdenberg, Arn M.J.M. (author), Mummery, Christine (author), Orlova, Valeria (author)Organ-on-a-chip (OoC) and microfluidic devices are conventionally produced using microfabrication procedures that require cleanrooms, silicon wafers, and photomasks. The prototyping stage often requires multiple iterations of design steps. A simplified prototyping process could therefore offer major advantages. Here, we describe a rapid and...journal article 2022
- document
-
de Graaf, W.M. (author), van Riet, T.C.T. (author), de Lange, J. (author), Kober, J. (author)Surprisingly little is known about tooth removal procedures. This might be due to the difficulty of gaining reliable data on these procedures. To improve our understanding of these procedures, machine learning techniques were used to design a multiclass classification model of tooth removal based on force, torque, and movement data recorded...journal article 2022
- document
-
van Beek, Janko (author), Teesing, Gwen (author), Oude Munnink, Bas B. (author), Meima, Abraham (author), Vriend, Henrike J. (author), Elzakkers, Jessica (author), de Graaf, Miranda (author), Langeveld, J.G. (author), Medema, G.J. (author)An outbreak of SARS-CoV-2 Alpha variant (Pango lineage B.1.1.7) was detected at a primary school (School X) in Lansingerland, the Netherlands, in December 2020. The outbreak was studied retrospectively, and population-based screening was used to assess the extent of virus circulation and decelerate transmission. Cases were SARS-CoV-2...journal article 2022
- document
-
de Graaf, G. (author), Vriesendorp, Maurits Frans (author), Amin Hassan, H.M. (author), French, P.J. (author)In this research fluorescent optochemical pH probes for the detection of ischaemia have been investigated. Myocardial ischaemia is the most prominent risk during heart surgery. During open heart surgery the heart is temporarily arrested and, since there no blood flowing, oxygen supply and removal of waste products is stopped and heart cells...journal article 2022
- document
-
Groen, Nathalie (author), Leenders, Floris (author), Mahfouz, A.M.E.T.A. (author), Munoz-Garcia, Amadeo (author), Muraro, Mauro J. (author), de Graaf, Natascha (author), Rabelink, Ton J. (author), Hoeben, Rob (author), Reinders, M.J.T. (author)The maintenance of pancreatic islet architecture is crucial for proper β-cell function. We previously reported that disruption of human islet integrity could result in altered β-cell identity. Here we combine β-cell lineage tracing and single-cell transcriptomics to investigate the mechanisms underlying this process in primary human islet...journal article 2021
- document
-
Nanda, S. (author), de Graaf, M. (author), Veefkind, j. Pepijn (author), Sneep, Maarten (author), Sun, J. (author), Levelt, Pieternel Felicitas (author)The TROPOspheric Monitoring Instrument (TROPOMI) level-2 aerosol layer height (ALH) product has now been released to the general public. This product is retrieved using TROPOMI's measurements of the oxygen A-band, radiative transfer model (RTM) calculations augmented by neural networks and an iterative optimal estimation technique. The...journal article 2020
- document
-
Lawson, Christopher E. (author), Nuijten, Guylaine H.L. (author), de Graaf, Rob M. (author), Jacobson, Tyler B. (author), Pabst, Martin (author), Stevenson, David M. (author), Jetten, Mike S.M. (author), Noguera, Daniel R. (author), McMahon, Katherine D. (author)Anaerobic ammonium-oxidizing (anammox) bacteria mediate a key step in the biogeochemical nitrogen cycle and have been applied worldwide for the energy-efficient removal of nitrogen from wastewater. However, outside their core energy metabolism, little is known about the metabolic networks driving anammox bacterial anabolism and use of...journal article 2020
- document
-
Giordano, G. (author), de Graaf, Lotte (author), Vasilakou, E. (author), Wahl, S.A. (author)We study dynamic metabolic models that describe the cellular responses of microorganisms under changing environmental conditions, such as substrate perturbations. Feast-famine experiments in Escherichia coli show that, despite the enormous extracellular perturbations, important quantities such as the cell energy charge remain practically...conference paper 2019
- document
-
Mkhoyan, T. (author), Wentink, Mark (author), van Paassen, M.M. (author), Mulder, Max (author), de Graaf, B (author)When coupled with additional degrees of freedom, centrifuge-based motion platforms can combine the agility of an hexapod-basedmotion platform with the ability of sustaining higher Glevels and an extended motion space. This combination of motion characteristics is required for realistic simulation of extreme flight scenarios. However, a false and...conference paper 2019
- document
-
Cai, Z. (author), van Veldhoven, Robert (author), Suy, Hilco (author), de Graaf, G. (author), Makinwa, K.A.A. (author), Pertijs, M.A.P. (author)<br/>book chapter 2019
- document
- Langhorst, Tom (author), de Graaf, Lennart (author) conference paper 2018
- document
-
Levelt, Pieternel Felicitas (author), Joiner, Joanna (author), Tamminen, Johanna (author), Veefkind, j. Pepijn (author), Bhartia, Pawan K. (author), Zweers, Deborah C.Stein (author), Duncan, Bryan N. (author), Streets, David G. (author), Eskes, Henk (author), Van Der, Ronald A. (author), McLinden, Chris (author), Fioletov, Vitali (author), Carn, Simon (author), De Laat, Jos (author), Deland, Matthew (author), Marchenko, Sergey (author), McPeters, Richard (author), Ziemke, Jerald (author), Fu, Dejian (author), Liu, Xiong (author), Pickering, Kenneth (author), Apituley, Arnoud (author), Abad, Gonzalo González (author), Arola, Antti (author), Boersma, Folkert (author), Miller, Christopher Chan (author), Chance, Kelly (author), de Graaf, M. (author), Hakkarainen, Janne (author), Hassinen, Seppo (author), Ialongo, Iolanda (author), Kleipool, Quintus (author), Krotkov, Nickolay (author), Li, Can (author), Lamsal, Lok (author), Newman, Paul (author), Nowlan, Caroline (author), Suleiman, Raid (author), Tilstra, Lieuwe Gijsbert (author), Torres, Omar (author), Wang, Huiqun (author), Wargan, Krzysztof (author)This overview paper highlights the successes of the Ozone Monitoring Instrument (OMI) on board the Aura satellite spanning a period of nearly 14 years. Data from OMI has been used in a wide range of applications and research resulting in many new findings. Due to its unprecedented spatial resolution, in combination with daily global coverage,...review 2018
- document
-
de Graaf, M. (author), Brown, Jessica (author), Donovan, D.P. (author)Marine stratocumulus clouds are important climate regulators, reflecting sunlight over a dark ocean background. A UV-depolarization lidar on Ascension, a small remote island in the south Atlantic, measured cloud droplet sizes and number concentration using an inversion method based on Monte Carlo (MC) modelling of multiple scattering in...conference paper 2018
- document
-
Cai, Z. (author), van Veldhoven, Robert (author), Suy, Hilco (author), de Graaf, G. (author), Makinwa, K.A.A. (author), Pertijs, M.A.P. (author)The measurement of carbon-dioxide (CO2) concentration is very important in home and building automation, e.g. to control ventilation in energy-efficient buildings. This application requires compact, low-cost sensors that can measure CO<sub>2</sub> concentration with a resolution of <200 ppm over a 2500ppm range. Conventional optical (NDIR...conference paper 2018