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Breve, T. (author), Liu, H. (author), Denkova, A.G. (author), Eelkema, R. (author)Gamma radiation triggered secondary crosslinking of dextran hydrogels leads to macroscopic hydrogel contraction. The authors use stable polymer hydrogels, prepared through azide-alkyne crosslinking, containing surplus alkyne groups. γ-irradiation of these gels leads to more alkyne crosslinking, enabling controlled increase of crosslink...journal article 2021
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Men, Y. (author), Breve, T. (author), Liu, H. (author), Denkova, A.G. (author), Eelkema, R. (author)We present a new light cleavable polymer containing o-nitrobenzene thioacetal groups in the main chain. By conjugation to a PEG block, we synthesized block copolymers capable of forming nanoparticles in aqueous solution. We studied drug encapsulation and release using the model drug Nile Red. Irradiation with UV-A light (365 nm) leads to...journal article 2021