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Barth, R. (author)
Genetic information encoded in the DNA sequences is maintained, replicated, and transcribed across the tree of life. Organisms evolved multiple hierarchical layers of chromosome organization which ensure that DNA can be contained but also processed within individual cells. This thesis focuses on SMC (Structural Maintenance of Chromosomes)...
doctoral thesis 2024
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Nederhoff, C.M. (author)
Tropical cyclones, known as hurricanes in the Atlantic and Northeast Pacific or typhoons in the Northwest Pacific, are intense storm systems characterized by strong rotating winds, heavy rainfall, and low atmospheric pressure. They form over warm tropical waters and are major drivers of coastal flooding in tropical and subtropical regions....
doctoral thesis 2024
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Blom, C.J. (author)
The long-range electron transport of exoelectrogenic bacterium G. sulfurreducens<br/>was recently discovered to be facilitated by a network of conductive protein wires. In<br/>chapter 1 we provide an overview of our current understanding of these protein wires.<br/>This newly discovered feature of the model organism for microbial fuel cells may...
doctoral thesis 2024
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Roy, M. (author)
Groundwater is typically a safe source of drinking water due to its stable and good microbial quality. However, the presence of geogenic arsenic (As) in groundwater, poses a serious health concern, impacting hundreds of millions of people worldwide. Prolonged groundwater consumption with elevated As levels can lead to chronic diseases, including...
doctoral thesis 2024
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Jungbauer, Alois (author), Satzer, Peter (author), Duerauer, Astrid (author), Azevedo, Ana (author), Aires-Barros, Raquel (author), Nilsson, Bernt (author), Farid, Suzy (author), Goldrick, Stephen (author), Ottens, M. (author)
The main objectives of bioprocesses are to reliably deliver drugs in a relatively short time frame with high quality within a tight regulatory framework. Bioprocesses are highly complex, the level of automation is moderate, and there is constant pressure to improve efficiency and costs. In addition, climate change and resource scarcity...
review 2024
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Hofbauer, B. (author)
This thesis explores the ethical challenges that a potential research program for solar climate engineering via Stratospheric Aerosol Injection (SAI) could incur. These ethical challenges are comprised of epistemic hurdles in relation to the research process, as well as societal questions of justice and the value of nature. The thesis proposes a...
doctoral thesis 2024
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Ramirez Montero, D.F. (author)
doctoral thesis 2024
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Olsthoorn, Mitchell (author)
Software testing is important to make sure that code works as intended. Traditionally, this verification process has relied on manual testing, which is not only time-consuming but also susceptible to human errors. Through the use of automated test case generation techniques, we can automate this process and reduce the time and effort needed to...
doctoral thesis 2024
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Shokrollahzadeh Behbahani, S. (author)
Induced seismicity refers to seismic events (earthquakes) triggered by human activities. Such events, even when characterized by relatively modest magnitudes, have the potential to jeopardize the safety of individuals, the surrounding environment, and infrastructure. <br/><br/>Production from hydrocarbon reservoirs can alter the in-situ stress...
doctoral thesis 2024
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Moghaddasi, Hanie (author)
Atrial Fibrillation (AF) is the most common tachyarrhythmia in the heart. Irregular RR intervals and the absence of a P wave before the QRS complex characterize AF. Although many studies have been done to detect atrial fibrillation, many aspects of this intricate disease need further analysis. AF is often diagnosed by the interpretation of multi...
doctoral thesis 2024
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Meyer, M. (author)
The spin of a single electron or hole provides an attractive candidate for implementing a quantum bit when confined in a semiconductor quantum dot. Such a spin qubit is characterized by long coherence and short gate times. High-fidelity single and two-qubit operations have been demonstrated as well. Additionally, semiconductor quantum dots have...
doctoral thesis 2024
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Kostiuchenko, A. (author)
Climate change is the main global concern today, triggering a transformative shift in several sectors, especially the construction industry. High carbon emissions during Portland cement (PC) production necessitate a gradual shift toward more environmentally friendly alternatives, such as alkali-activated materials (AAMs). AAMs offer a promising,...
doctoral thesis 2024
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van Duivendijk, J. (author)
The dissertation focussed on the kind of closure methods used, in the past and at present, to repair breached dikes and to close tidal channels by simple means. By simple means one must think about the application by (mainly) manual labour of local materials and small-scale tools and equipment. The closure of tidal channels is also required in...
doctoral thesis 2024
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Kroon, J. (author)
Because of the large uncertainties associated with rising sea levels, present coastal management is inclined towards utilizing soft, nature-inclusive, and adaptive measures over traditional hard protection structures. This shift towards more sustainable and multi-functional solutions is often called Building with Nature. In the coastal zone,...
doctoral thesis 2024
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le Poole, J.J. (author)
Early-stage design of complex ships is of an iterative nature due to a coevolving problem definition and solution generation. In addition, design decisions are often made based on assumptions early on. To inform the stakeholder dialogue to support the definition of the design problem, designers need to gain insight into the technical feasibility...
doctoral thesis 2024
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Lakshminarayanan, V. (author)
Supramolecular hydrogels that are formed from low molecular weight gelators are a new class of soft materials which are gaining prominence. Depending on their molecular make up, these soft gel materials are formed based on different triggers, pH being one among them. In order to build applications with pH-triggered supramolecular gelators, it is...
doctoral thesis 2024
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Veltmeijer, A.V. (author)
Activities underground, such as gas extraction or fluid injection, can disturb the natural stresses present and can cause human-induced earthquakes along pre-existing faults. Even though they are related to engineering, these earthquakes are currently unpredictable. Monitoring and understanding how these earthquakes occur are essential for a...
doctoral thesis 2024
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van Beljouw, S.P.B. (author)
This dissertation provides an experimental and conceptual characterization of Craspase, a CRISPR-controlled protease. The array of functionalities inherent to Craspase — including precise protein cleavage, guided RNA recognition, and self-regulatory capabilities — highlights the complexity that can emerge from the endless bacterium-virus...
doctoral thesis 2024
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Pak, A. (author)
Currently, neurostimulation holds the capability of treating symptoms associated with epilepsy, essential tremor, depression, migraine, incontinence, Parkinson's, Tourette's, and other diseases and disorders. Given the constant evolution in the field of biomedical technology and the increasing demand for advanced solutions in neural interface...
doctoral thesis 2024
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Kim, S. (author)
Automated vehicles are anticipated to not only improve safety and comfort but also redefine the nature of driver-vehicle interactions. With these advancements, drivers in automated vehicles share the monitoring and supervising role with the system, creating a unique human-machine team. In this relation, beyond technical excellence, it is...
doctoral thesis 2024
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