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Aydogmus, H. (author), van Ginkel, H.J. (author), Galiti, Anna-Danai (author), Hu, Michel (author), Frimat, Jean-Philippe (author), van den Maagdenberg, Arn (author), Zhang, Kouchi (author), Mastrangeli, Massimo (author), Sarro, Pasqualina M (author)Continuous monitoring of tissue microphysiology is a key enabling feature of the organ-on-chip (OoC) approach for drug screening and disease modeling. Sensing charged species in OoC tissue microenvironments is thereby essential. However, the inherently small (i.e., cm) size of OoC devices poses the challenging requirement to integrate...conference paper 2021
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Mastrangeli, Massimo (author), Aydogmus, H. (author), Dostanic, M. (author), Motreuil-Ragot, P.A. (author), Revyn, N. (author), de Wagenaar, B. (author), Dekker, R. (author), Sarro, Pasqualina M (author)Stemming from the convergence of tissue engineering and microfluidics, organ-on-chip (OoC) technology can reproduce in vivo-like dynamic microphysiological environments for tissues in vitro. The possibility afforded by OoC devices of realistic recapitulation of tissue and organ (patho)physiology may hold the key to bridge the current...conference paper 2021
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Romijn, J. (author), Vollebregt, S. (author), van Zeijl, H.W. (author), Zhang, Kouchi (author), Leijtens, Johan (author), Sarro, Pasqualina M (author)In this paper we present a sun position sensor platform with a scalable approach for the 3D integration of the sensor optics. This would facilitate the sun position sensor miniaturization, reduces fabrication cost and mitigates the need for sensor calibration. The sun position sensor platform is implemented in a seven mask BICMOS technology with...conference paper 2021
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Bonaldi, Michele (author), Borrielli, Antonio (author), Chowdhury, Avishek (author), Di Giuseppe, Gianni (author), Morana, B. (author), Piergentili, Paolo (author), Prodi, Giovanni A. (author), Sarro, Pasqualina M (author), Serra, E. (author)Abstract: Phenomenological models aiming to join gravity and quantum mechanics often predict effects that are potentially measurable in refined low-energy experiments. For instance, modified commutation relations between position and momentum, that account for a minimal scale length, yield a dynamics that can be codified in additional...journal article 2020
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Dostanic, M. (author), Stein, Jeroen (author), Windt, Laura (author), van Meer, Berend (author), Bellin, Milena (author), Orlova, Valeria (author), Mastrangeli, Massimo (author), Mummery, Christine (author), Sarro, Pasqualina M (author)We present a wafer-scale fabricated, PDMS-based platform for culturing miniaturized engineered heart tissues (EHTs) which allows highly accurate measurements of the contractile properties of these tissues. The design of the platform is an anisometrically downscaled version of the Heart-Dyno system, consisting of two elastic micropillars inside...journal article 2020
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- Windt, Laura (author), Dostanic, M. (author), Stein, Jeroen (author), Meraviglia, Viviana (author), Campostrini, Giulia (author), Bellin, Milena (author), Orlova, Valeria (author), Mastrangeli, Massimo (author), Sarro, Pasqualina M (author), van Meer, Berend (author), Mummery, Christine L. (author) poster 2020
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- Windt, Laura (author), Dostanic, M. (author), Stein, Jeroen (author), Meraviglia, Viviana (author), Campostrini, Giulia (author), Bellin, Milena (author), Orlova, Valeria (author), Mastrangeli, Massimo (author), Sarro, Pasqualina M (author), van Meer, Berend (author), Mummery, Christine (author) poster 2020
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Alfaro Barrantes, J.A. (author), Mastrangeli, Massimo (author), Thoen, David (author), Visser, Sven (author), Bueno Lopez, J. (author), Baselmans, J.J.A. (author), Sarro, Pasqualina M (author)This paper presents the fabrication and electrical characterization of superconducting high-aspect ratio through-silicon vias DC-sputtered with aluminum. Fully conformal and void-free coating of 300 μm-deep and 50 μmwide vias with Al, a CMOS-compatible and widely available superconductor, was made possible by tailoring a funneled sidewall...journal article 2020
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Motreuil-Ragot, P.A. (author), Hunt, A. (author), Kasi, Dhanesh (author), Brajon, B. (author), van den Maagdenberg, Arn M.J.M. (author), Orlova, Valeria (author), Mastrangeli, Massimo (author), Sarro, Pasqualina M (author)Organ-on-chip (OoC) devices are in rising demand for high-throughput and low-cost development and toxico-logical screening of chemicals and pharmaceuticals, as they accurately mimic in vitro physiological conditions as in the human body. In particular, OoCs are urgently needed for screening cardiovascular drug toxicity. Physiological relevance...conference paper 2020
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Chowdhury, A. (author), Vezio, P. (author), Bonaldi, M. (author), Borrielli, A. (author), Marino, F. (author), Morana, B. (author), Prodi, G. A. (author), Sarro, Pasqualina M (author), Serra, E. (author), Marin, F. (author)Recent optomechanical experiments have observed nonclassical properties in macroscopic mechanical oscillators. A key indicator of such properties is the asymmetry in the strength of the motional sidebands produced in the probe electromagnetic field, which is originated by the noncommutativity between the oscillator ladder operators. Here we...journal article 2020
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Sokolovskij, R. (author), Zhang, Jian (author), Zheng, Hongze (author), Li, Wenmao (author), Jiang, Y. (author), Yang, Gaiying (author), Yu, H. (author), Sarro, Pasqualina M (author), Zhang, Kouchi (author)The present work reports on the hydrogen gas detection properties of Pt-AlGaN/GaN high electron mobility transistor (HEMT) sensors with recessed gate structure. Devices with gate recess depths from 5 to 15 nm were fabricated using a precision cyclic etching method, examined with AFM, STEM and EDS, and tested towards H 2 response at high...journal article 2020
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Ricciardella, F. (author), Vollebregt, S. (author), Polichetti, Tiziana (author), Sarro, Pasqualina M (author), Duesberg, Georg S. (author)Humidity sensing is fundamental in some applications, as humidity can be a strong interferent in the detection of analytes under environmental conditions. Ideally, materials sensitive or insensitive towards humidity are strongly needed for the sensors used in the first or second case, respectively. We present here the sensing properties of...journal article 2020
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de Rijk, T.M. (author), Hu, Michel (author), Frimat, Jean-Philippe (author), van den Maagdenberg, Arn M.J.M. (author), Sarro, Pasqualina M (author), Mastrangeli, Massimo (author)In vitro study of high-level neurobiological systems requires three-dimensional (3D) neuronal cultures [1]. Meas-uring responses along all three spatial dimensions is critical to record electric activity inside 3D neuronal models, such as organoids and other 3D brain tissue constructs. However, this lies beyond the capacity of 2D microelec-trode...poster 2020
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Aydogmus, H. (author), Dostanic, M. (author), Jahangiri, M. (author), Sinha, Rajarshi (author), Quiros Solano, W.F. (author), Mastrangeli, Massimo (author), Sarro, Pasqualina M (author)We present an extremely compact field effect transistor (FET)-based electrochemical sensor for in situ real-time and label-free measurement of ion concentrations in the cell culture area of organs-on-chip (OoCs) devices. This sensor replaces the functionality of an external reference electrode, crucial in standard electrochemical sensing, by...conference paper 2020
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Aydogmus, H. (author), van Ginkel, H.J. (author), Mastrangeli, Massimo (author), Zhang, Kouchi (author), Sarro, Pasqualina M (author)<br/>poster 2020
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Vezio, P. (author), Chowdhury, A. (author), Bonaldi, M. (author), Borrielli, Antonio (author), Marino, F. (author), Morana, B. (author), Prodi, G.A. (author), Sarro, Pasqualina M (author), Serra, E. (author), Marin, F. (author)We experimentally investigate a mechanical squeezed state realized in a parametrically modulated membrane resonator embedded in an optical cavity. We demonstrate that a quantum characteristic of the squeezed dynamics can be revealed and quantified even in a moderately warm oscillator, through the analysis of motional sidebands. We provide a...journal article 2020
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Ricciardella, F. (author), Vollebregt, S. (author), Boshuizen, B. (author), Danzl, F.J.K. (author), Cesar, Ilkay (author), Spinelli, Pierpaolo (author), Sarro, Pasqualina M (author)Chemical vapour deposition (CVD) has emerged as the dominant technique to combine high quality with large scale production of graphene. The key challenge for CVD graphene remains the transfer of the film from the growth substrate to the target substrate while preserving the quality of the material. Avoiding the transfer process of single or...journal article 2020
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Sun, J. (author), Zhang, Shuo (author), Zhan, Teng (author), Liu, Zewen (author), Wang, Junxi (author), Yi, Xiaoyan (author), Li, Jinmin (author), Sarro, Pasqualina M (author), Zhang, Kouchi (author)A high responsivity and controllable recovery ultraviolet (UV) photodetector based on a tungsten oxide (WO<sub>3</sub>) gate AlGaN/GaN heterostructure with an integrated micro-heater is reported for the first time. The WO<sub>3</sub>nanolayer was deposited by physical vapor deposition (PVD) for deep UV absorption and the micro-heater was...journal article 2020
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Pezone, R. (author), Vollebregt, S. (author), Sarro, Pasqualina M (author), Unnikrishnan, S. (author)Control of the morphology of carbon nanotubes (CNT) is fundamental for many applications. It is known that the catalyst distributions influence the vertical alignment and the height of the CNT. In this work we investigate the influence of the pre-anneal time and reductant gases, specifically NH<sub>3</sub> and H<sub>2</sub> as well as...journal article 2020
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Sokolovskij, R. (author), Zhang, Jian (author), Zheng, Hongze (author), Li, Wenmao (author), Jiang, Yang (author), Yang, Gaiying (author), Yu, Hongyu (author), Sarro, Pasqualina M (author), Zhang, Kouchi (author)The present work reports on the hydrogen gas detection properties of Pt-AlGaN/GaN high electron mobility transistor (HEMT) sensors with recessed gate structure. Devices with gate recess depths from 5 to 15 nm were fabricated using a precision cyclic etching method, examined with AFM, STEM and EDS, and tested towards H2 response at high...journal article 2020