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Gisch, Debora L. (author), Brennan, Michelle (author), Lake, Blue B. (author), Basta, Jeannine (author), Keller, Mark S. (author), P. Gonçalves, Joana (author), Migas, L.G. (author), Van de Plas, Raf (author), Lardenoije, R. (author)There is a need to define regions of gene activation or repression that control human kidney cells in states of health, injury, and repair to understand the molecular pathogenesis of kidney disease and design therapeutic strategies. Comprehensive integration of gene expression with epigenetic features that define regulatory elements remains a...journal article 2024
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Alfrink, Kars (author), Keller, A.I. (author), Doorn, N. (author), Kortuem, Gerd (author)Local governments increasingly use artificial intelligence (AI) for automated decision-making. Contestability, making systems responsive to dispute, is a way to ensure they respect human rights to autonomy and dignity. We investigate the design of public urban AI systems for contestability through the example of camera cars: human-driven...conference paper 2023
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Mottram, J. Toby (author), Tromp, Liesbeth (author), Pavlovic, M. (author), Ramôa Correia, João (author), Keller, Thomas (author), Sena-Cruz, José (author)It was essential in the European Technical Specification for the Design of Fibre- Polymer Composite Structures (prCEN/TS 19101) to provide an Ultimate Limit State design procedure for a failure criterion for multi-ply laminates subjected to in-plane combined actions, which will give a generically applicable and a simple design procedure. This...conference paper 2022
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Pavlovic, M. (author), Christoforidou, A. (author), Keller, Thomas (author)Challenges of reliable prediction of resistance of bonded joints lie in the complexity of stress concentrations, multiple crack paths, mode-mixity and sudden crack propagation. The new Technical Specification for Design of fibre-polymer composite structures (TS) is bridging this gap by providing comprehensive sets of design recommendations and...conference paper 2022
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Nejad, Amir R. (author), Keller, Jonathan (author), Guo, Yi (author), Sheng, Shawn (author), Polinder, H. (author), Watson, S.J. (author), Dong, J. (author), Qin, Z. (author), Ebrahimi, Amir (author)This paper presents the state-of-the-art technologies and development trends of wind turbine drivetrains – the system that converts kinetic energy of the wind to electrical energy – in different stages of their life cycle: design, manufacturing, installation, operation, lifetime extension, decommissioning and recycling. Offshore development and...review 2022
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Mulder, W. (author), Patty, C. H.Lucas (author), Spadaccia, Stefano (author), Pommerol, Antoine (author), Demory, Brice Olivier (author), Keller, Christoph U. (author), Kühn, Jonas G. (author), Snik, Frans (author), Stam, D.M. (author)Does life exist outside our Solar System A first step towards searching for life outside our Solar System is detecting life on Earth by using remote sensing applications. One powerful and unambiguous biosignature is the circular polarization resulting from the homochirality of biotic molecules and systems. We aim to investigate the...conference paper 2022
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Alfrink, Kars (author), Keller, A.I. (author), Doorn, N. (author), Kortuem, G.W. (author)The increasing use of artificial intelligence (AI) by public actors has led to a push for more transparency. Previous research has conceptualized AI transparency as knowledge that empowers citizens and experts to make informed choices about the use and governance of AI. Conversely, in this paper, we critically examine if transparency-as...journal article 2022
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Alfrink, Kars (author), Keller, A.I. (author), Kortuem, G.W. (author), Doorn, N. (author)As the use of AI systems continues to increase, so do concerns over their lack of fairness, legitimacy and accountability. Such harmful automated decision-making can be guarded against by ensuring AI systems are contestable by design: responsive to human intervention throughout the system lifecycle. Contestable AI by design is a small but...journal article 2022
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Abedini, Abbas (author), Keller, Wolfgang (author), Amiri Simkooei, A. (author)Mass concentration (mascon) solutions for GRACE (Gravity Recovery and Climate Experiment) data are widely used in various regional-to-global mass change studies. The current advances in the mascon solution have mainly concentrated on improving the spatial resolution of the solution, enhancing the applied least-squares regularization, and the...journal article 2021
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Prasanth, H. (author), Caban, Miroslav (author), Keller, Urs (author), Courtine, Grégoire (author), Ijspeert, Auke J. (author), Vallery, H. (author), Von Zitzewitz, Joachim (author)Gait analysis has traditionally been carried out in a laboratory environment using expensive equipment, but, recently, reliable, affordable, and wearable sensors have enabled integration into clinical applications as well as use during activities of daily living. Real-time gait analysis is key to the development of gait rehabilitation techniques...journal article 2021
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Konings, Alexandra G. (author), Saatchi, Sassan S. (author), Frankenberg, Christian (author), Keller, Michael (author), Leshyk, Victor (author), Anderegg, William R.L. (author), Humphrey, Vincent (author), Steele-Dunne, S.C. (author), Wang, Yujie (author)Droughts in a warming climate have become more common and more extreme, making understanding forest responses to water stress increasingly pressing. Analysis of water stress in trees has long focused on water potential in xylem and leaves, which influences stomatal closure and water flow through the soil-plant-atmosphere continuum. At the...review 2021
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Patty, C. H.Lucas (author), Kühn, Jonas G. (author), Lambrev, Petar H. (author), Spadaccia, Stefano (author), Keller, C.U. (author), Mulder, W. (author), Pallichadath, V. (author), Snik, Frans (author), Stam, D.M. (author)Context. Homochirality is a generic and unique property of life on Earth and is considered a universal and agnostic biosignature. Homochirality induces fractional circular polarization in the incident light that it reflects. Because this circularly polarized light can be sensed remotely, it can be one of the most compelling candidate...journal article 2021
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Snellen, Ignas (author), Snik, F (author), Kenworthy, M (author), Keller, C.U. (author), De Mooij, Eric (author), Albrecht, S. (author), Krause, O (author), Kreidberg, L. (author), Stam, D.M. (author)In this White Paper, which was submitted in response to the European Space Agency (ESA) Voyage 2050 Call, we recommend the ESA plays a proactive role in developing a global collaborative effort to construct a large high-contrast imaging space telescope, e.g. as currently under study by NASA. Such a mission will be needed to characterize a...journal article 2021
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Keller, A. (author), Geissberger, R. (author), Studer, J. (author), Leone, F. (author), Stefaniak, D. (author), Pascoe, J.A. (author), Dransfeld, C.A. (author), Masania, K. (author)The effect of ply thickness on the notch sensitivity and bearing properties on carbon fibre reinforced polymer composites and their hybrid laminates with steel foils were studied. Laminates with ply thicknesses of 0.3 mm and 0.03 mm comprising of CFRP and hybrid laminates were manufactured and characterized using tension, open hole tension...journal article 2021
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Grassel, Joshua (author), Keller, Alfred Craig (author), Hill, Alessandro (author), Schulte, F. (author)The craft beer supply chain in the USA differs from the supply chain of macro breweries in its structure, handled volumes and product shelf-life. In this work, we study how these smaller craft breweries can benefit from transparency in their supply chain. We consider additional information sharing of orders and inventories at downstream nodes...book chapter 2021
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Keller, Christoph U. (author), Snik, Frans (author), Patty, C. H.Lucas (author), Klindzic, D. (author), Krasteva, Mariya (author), Doelman, David S. (author), Wijnen, T.P.G. (author), Pallichadath, V. (author), Stam, D.M. (author)Many biologically produced chiral molecules such as amino acids and sugars show a preference for left or right handedness (homochirality). Light reflected by biological materials such as algae and leaves therefore exhibits a small amount of circular polarization that strongly depends on wavelength. Our Life Signature Detection polarimeter ...conference paper 2020
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Alfrink, Kars (author), Doorn, N. (author), Keller, A.I. (author), Kortuem, G.W. (author)The increasing use of algorithms in cities has come under scrutiny. Transparency is widely seen as a way to ensure their fairness and accountability. We investigate how al- gorithmic transparency helps citizens understand smart electric vehicle charge points and how its conception differs between experts and citizens. Using a research-through-...conference paper 2020
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Studer, Julia (author), Dransfeld, C.A. (author), Jauregui Cano, Jon (author), Keller, Andre (author), Wink, Marianne (author), Masania, K. (author), Fiedler, Bodo (author)To reduce the cycle time of structural, automotive thermoplastic composites, we investigated the potential of direct thermoplastic melt impregnation of glass fabrics using an injection moulding process. At the high pressures that occur during the process, the effect of the fabric architecture on the impregnation, compaction, volume fraction...journal article 2019
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Li, Fankang (author), Shen, Jiazhou (author), Parnell, S.R. (author), Thaler, Alex N. (author), Matsuda, Masaaki (author), Keller, Thomas (author), Delaire, Olivier (author), Pynn, Roger (author), Fernandez-Baca, Jaime A. (author)The energy resolution of the conventional way of measuring a small change in a phonon dispersion curve using neutron scattering is restricted by the relatively coarse intrinsic resolution ellipsoid of the neutron triple-axis spectrometer (TAS). By implementing inelastic neutron spin echo on the host TAS using the Larmor precession of the...journal article 2019
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Keller, Kirill (author), Khramenkova, E. (author), Slabov, Vladislav (author), Musin, Albina (author), Kalashnikov, Alexander (author), Vinogradov, Alexandr V. (author), Pidko, E.A. (author)Here we report the methodology for nanocomposite fabrication based on the inkjet printing technique. Doped TiO<sub>2</sub> nanoparticles with Sc contents up to 10 wt.% were synthesized and adapted towards a facile fabrication of microscale structures and thin film printing. Implementation of the state-of-the-art low-temperature synthesis...journal article 2019