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Kujala, P. (author), Raymond, C.R. (author), Romeijn, M. (author), Godsave, S.F. (author), Van Kasteren, S.I. (author), Wille, H. (author), Prusiner, S.B. (author), Mabbott, N.A. (author), Peters, P.J. (author)After oral exposure, prions are thought to enter Peyer's patches via M cells and accumulate first upon follicular dendritic cells (FDCs) before spreading to the nervous system. How prions are actually initially acquired from the gut lumen is not known. Using high-resolution immunofluorescence and cryo-immunogold electron microscopy, we report...journal article 2011
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Geraldes, C.F.G.C. (author), Djanashvili, K. (author), Peters, J.A. (author)Recently, many research activities in medical diagnosis have been devoted to molecular imaging with MRI. A key issue is the evaluation of molecular targets that allow the early detection and characterization of diseases and the assessment of the effects of therapy. The majority of the current targeting vectors are peptides and proteins; reports...journal article 2010
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- Peters, V.A.J. (author) patent 2010
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Peters, F.H.J. (author), De Brito, M.P. (author)This article investigates the application of the Cradle-to-Cradle approach to the electric scooter vehicle, and how the concept of leasing can be used as a means to make it operational. This research is a result of a research project with Eco-Movement, a Dutch firm currently selling electric scooters imported mainly from Asia. Eco-Movement is...conference paper 2010
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Schühle, D.T. (author), Van Rijn, P. (author), Laurent, S. (author), Van der Elst, L. (author), Muller, R.N. (author), Stuart, M.C.A. (author), Schatz, J. (author), Peters, J.A. (author)Paramagnetic liposomes used as contrast agents in magnetic resonance imaging (MRI) often suffer from low efficacies because of slow water diffusion through the membrane. We present an approach to overcome this limitation by incorporation of a calix[4]arene based agent that expresses the chelates towards the bulk water.journal article 2010
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Sani, M. (author), Houben, E.N.G. (author), Geurtsen, J. (author), Pierson, J. (author), De Punder, K. (author), Van Zon, M. (author), Wever, B. (author), Piersma, S.R. (author), Jiménez, C.R. (author), Peters, P.J. (author)The cell envelope of mycobacteria, a group of Gram positive bacteria, is composed of a plasma membrane and a Gramnegative-like outer membrane containing mycolic acids. In addition, the surface of the mycobacteria is coated with an illcharacterized layer of extractable, non-covalently linked glycans, lipids and proteins, collectively known as the...journal article 2010
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Van Ravesteijn, V.F. (author), Van Wijk, C. (author), Vos, F.M. (author), Truyen, R. (author), Peters, J.F. (author), Stoker, J. (author), Van Vliet, L.J. (author)We present a computer-aided detection (CAD) system for computed tomography colonography that orders the polyps according to clinical relevance. TheCADsystem consists of two steps: candidate detection and supervised classification. The characteristics of the detection step lead to specific choices for the classification system. The candidates are...journal article 2010
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Schühle, D.T. (author), Poláek, M. (author), Luke, I. (author), Chauvin, T. (author), Tóth, E. (author), Schatz, J. (author), Hanefeld, U. (author), Stuart, M.C.A. (author), Peters, J.A. (author)A pyridine-N-oxide functionalized DOTA analogue has been conjugated to a calix[4]arene and the corresponding Gd-complex was characterized with respect to its suitability as MRI contrast agent. The compound forms spherical micelles in water with a cmc of 35 mMand a radius of 8.2 nm. The relaxivity of these aggregates is 31.2 s-1 mM-1 at 25ºC and...journal article 2009
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Tromp-van Meerveld, H.J. (author), James, A.L. (author), McDonnell, J.J. (author), Peters, N.E. (author)Although many hillslope hydrologic investigations have been conducted in different climate, topographic, and geologic settings, subsurface stormflow remains a poorly characterized runoff process. Few, if any, of the existing data sets from these hillslope investigations are available for use by the scientific community for model development and...journal article 2008
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Roelofsen, F. (author), Buma, J. (author), Oude Essink, G. (author), Garming, L. (author), Van Oostrom, N. (author), Gehrels, J. (author), Peters, T. (author), Van Meerten, H. (author), Vergroesen, T. (author), Penailillo, R. (author)Delft en omliggende gemeenten zullen in de komende jaren moeten anticiperen op de mogelijke veranderingen in het onttrekkingsregime voor grondwater van DSM Gist en de geplande aanleg van de spoortunnel onder Delft. Deze veranderingen hebben invloed op het watersysteem en daarmee op het waterbeheer. In het kader van het onderzoeksprogramma ...report 2007
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Investigation implementation clamping strength in ZSteen: Onderzoek implementatie klemming in ZSteenPeters, D.J. (author), Pfeiffer, A. (author)Dit rapport is een onderdeel van het Onderzoekzoeksprogramma Kennisleemtes Steenbekledingen. Het betreft onderzoek op deelplan 7.3 naar de kennisleemte omtrent de bijdrage van klemming aan de stabiliteit van steenbekledingen onder golfaanval. Met het programma ZSteen worden stijghoogteverschillen berekend die werken op de toplaagelementen van de...report 2007
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Peters, D.J. (author)This report belongs to the research programme on unknown aspects of Block Revetment systems. The stability of block revetments under wave loading is presumed to benefit from clamping forces. In previous studies a physical model for clamping forces was developed and verified. The existing design and design checking software code SteenToets...report 2007
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Blom, J.A.H. (author), Van Nieuwenhuijzen, L. (author), Peters, D.J. (author)Dit rapport is een onderdeel van het Onderzoeksprogramma Kennisleemtes Steenbekledingen. Het betreft onderzoek op deelplan 7.3 naar de kennisleemte omtrent de bijdrage van klemming aan de stabiliteit van steenbekledingen onder golfaanval. Het beschrijft de trekproeven en schuifproeven die in het veld zijn uitgevoerd ter verificatie van het...report 2007
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Labeling the pulmonary arterial tree in CT images for automatic quantification of pulmonary embolismPeters, R.J.M. (author), Marquering, H.A. (author), Dogan, H. (author), Hendriks, E.A. (author), De Roos, A. (author), Reiber, J.H.C. (author), Stoel, B.C. (author)Contrast-enhanced CT Angiography has become an accepted diagnostic tool for detecting Pulmonary Embolism (PE). The CT obstruction index proposed by Qanadli, which is based on the number of obstructed arterial segments, enables the quantification of PE severity. Because the required manual identification of twenty arterial segments is time...conference paper 2007
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Kroon, M.C. (author), Shariati, A. (author), Florusse, L.J. (author), Peters, C.J. (author), Van Spronsen, J. (author), Witkamp, G.J. (author), Sheldon, R.A. (author), Gutkowski, K.I. (author)The invention is directed to a process for carrying out a chemical reaction in an ionic liquid as solvent and CO2 as cosolvent, in which process reactants are reacted in a homogeneous phase at selected pressure and temperature to generate a reaction product at least containing an end-product of the reaction, and upon completion of the reaction a...patent 2006
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Van 't Hof, A. (author), Peters, C.J. (author), De Leeuw, S.W. (author)The conventional Gibbs-Duhem integration method is very convenient for the prediction of phase equilibria of both pure components and mixtures. However, it turns out to be inefficient. The method requires a number of lengthy simulations to predict the state conditions at which phase coexistence occurs. This number is not known from the outset of...journal article 2006
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Van 't Hof, A. (author), De Leeuw, S.W. (author), Peters, C.J. (author)Gibbs-Duhem integration implies the numerical integration of a Clapeyron equation. To start the numerical integration, an initial coexistence point and a corresponding initial slope of the Clapeyron equation are needed. In order to apply Gibbs-Duhem integration to all kinds of systems at diverse physical conditions, one has to investigate and...journal article 2006
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Peters, C.J. (author), Sloan, E.D. (author)The invention relates to the storage of hydrogen. The invention relates especially to storing hydrogen in a clathrate hydrate. The clathrate hydrate according to the present invention originates from a composition, which comprises water and hydrogen, as well as a promotor compound. The promotor compound provides a large reduction of the pressure...patent 2005
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Peters, D.J. (author)Dit rapport is een onderdeel van het Onderzoekzoeksprogramma Kennisleemtes Steenbekledingen. Het betreft onderzoek op deelplan 7.3 naar de kennisleemte omtrent de bijdrage van klemming aan de stabiliteit van steenbekledingen onder golfaanval. Er is een mechanicamodel beschikbaar voor de bijdrage van klemming. Dit model gaat uit van de...report 2004
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Peters, D.J. (author)This report studies clamping phenomena in placed revetments on the Dutch dikes. One of the reasons of placing stones is that the stability of the single stones increases. Pull–out tests on single stones show a strength up to 10 times the single stone weight. In present standardized design methods for placed revetments there is no significant...report 2003