Engineering ketoreductases for the enantioselective synthesis of chiral alcohols

The use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated enzymes, in the highly enantiospecific reduction of prochiral ketones is reviewed. The homochiral alcohol products are key intermediates in, for example, pharmaceuticals synthesis. The application of sophisticated protein engineering and enzyme...

Investigation of Unclamped Inductive Switch Characteristics in 4H-SiC MOSFETs With Different Cell Topologies

To investigate the unclamped inductive switch (UIS) characteristics, 1200 V silicon carbide (SiC) planar MOSFETs with four cell topologies of linear, current sharing linear, square, and hexagon are designed and manufactured. The experimental platform was built and tested. The results show that the single pulse avalanche energy density of the...

A novel 4H-SiC multiple stepped SGT MOSFET with improved high frequency figure of merit

A novel 4H-SiC Multiple Stepped SGT MOSFET (MSGT-MOSFET) is presented and investigated utilizing TCAD simulations in this paper. We have quantitatively studied the characteristics of the device through simulation modeling and physical model calculations, and comparatively analyzed the performance and application prospects of this novel device...

A 2m-Range 711uW Body Channel Communication Transceiver Featuring Dynamically-Sampling Bias-Free Interface Front End

Body Channel Communication (BCC) offers a low-loss signal transmission medium for ultra-low-power wearable devices on human body [1]. However, the effective communication range on human body is limited to less than 1m in the state-of-the-art BCC transceivers [2], where the signal loss at the interface of body surface and BCC receiver remains to...

A Series of Ternary Metal Chloride Superionic Conductors for High-Performance All-Solid-State Lithium Batteries

Understanding the relationship between structure, ionic conductivity, and synthesis is the key to the development of superionic conductors. Here, a series of Li_3-3_xM₁₊_xCl₆ (−0.14 < x ≤ 0.5, M = Tb, Dy, Ho, Y, Er, Tm) solid electrolytes with orthorhombic and trigonal structures are...

A Crystal-Less Clock Generation Technique for Battery-Free Wireless Systems

The size of wireless systems is required to be reduced in many applications, such as ultra-low-power sensor nodes and wearable/implantable devices, where battery and crystal are the two main bottlenecks in system miniaturization. In recent years, battery-free radios based on wireless power transfer (WPT) have shown great potential in...

Determination of the intrinsic α/γ interface mobility during massive transformations in interstitial free Fe-X alloys

Kinetics of the austenite (γ) to ferrite (α) transformation and the reverse ferrite (α) to austenite (γ) transformation in a series of Fe-X (X = Ni, Mn and Co) binary alloys has been experimentally and theoretically investigated. A transition from partitioning to partitionless transformation has been predicted to occur during both the γ→α and...