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Sabidussi, E. R. (author), Klein, S. (author), Caan, M. W.A. (author), Bazrafkan, S. (author), den Dekker, A. J. (author), Sijbers, J. (author), Niessen, W.J. (author), Poot, D.H.J. (author)
In this paper, we propose the use of Recurrent Inference Machines (RIMs) to perform T<sub>1</sub> and T<sub>2</sub> mapping. The RIM is a neural network framework that learns an iterative inference process based on the signal model, similar to conventional statistical methods for quantitative MRI (QMRI), such as the Maximum Likelihood...
journal article 2021
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Huizinga, W. (author), Poot, D.H.J. (author), Vinke, E. J. (author), Wenzel, F. (author), Bron, E. E. (author), Ikram, M. A. (author), Niessen, W.J. (author), Vernooij, M. W. (author), Klein, S. (author)
For the segmentation of magnetic resonance brain images into anatomical regions, numerous fully automated methods have been proposed and compared to reference segmentations obtained manually. However, systematic differences might exist between the resulting segmentations, depending on the segmentation method and underlying brain atlas. This...
journal article 2021
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Cremers, Lotte G.M. (author), Huizinga, Wyke (author), Niessen, W.J. (author), Krestin, Gabriel P. (author), Poot, D.H.J. (author), Ikram, M. Arfan (author), Lötjönen, Jyrki (author), Klein, S. (author), Vernooij, Meike W. (author)
Background: Identifying persons at risk for cognitive decline may aid in early detection of persons at risk of dementia and to select those that would benefit most from therapeutic or preventive measures for dementia. Objective: In this study we aimed to validate whether cognitive decline in the general population can be predicted with...
journal article 2020
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van Valenberg, W. (author), Klein, S. (author), Vos, F.M. (author), Koolstra, Kirsten (author), van Vliet, L.J. (author), Poot, D.H.J. (author)
Quantitative MRI methods that estimate multiple physical parameters simultaneously often require the fitting of a computational complex signal model defined through the Bloch equations. Repeated Bloch simulations can be avoided by matching the measured signal with a precomputed signal dictionary on a discrete parameter grid (i.e. lookup table...
journal article 2020
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Poot, D.H.J. (author), van der Heijden, R.A.J. (author), van Middelkoop, Marienke (author), Oei, Edwin H.G. (author), Klein, S. (author)
Purpose: To identify the optimal combination of pharmacokinetic model and arterial input function (AIF) for quantitative analysis of blood perfusion in the patellar bone using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods: This method design study used a random subset of five control subjects from an...
journal article 2018
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huizinga, w (author), Poot, D.H.J. (author), Vernooij, Meike W. (author), Roshchupkin, G.V. (author), bron, E.E. (author), Ikram, M.A. (author), Rueckert, D. (author), Niessen, W.J. (author), Klein, S. (author)
Both normal aging and neurodegenerative disorders such as Alzheimer's disease (AD) cause morphological changes of the brain. It is generally difficult to distinguish these two causes of morphological change by visual inspection of magnetic resonance (MR) images. To facilitate making this distinction and thus aid the diagnosis of...
journal article 2018
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Guyader, Jean Marie (author), Huizinga, W. (author), Poot, D.H.J. (author), van Kranenburg, Matthijs (author), Uitterdijk, André (author), Niessen, W.J. (author), Klein, S. (author)
The most widespread technique used to register sets of medical images consists of selecting one image as fixed reference, to which all remaining images are successively registered. This pairwise scheme requires one optimization procedure per pair of images to register. Pairwise mutual information is a common dissimilarity measure applied to a...
journal article 2018
document
van der Heijden, R.A.J. (author), Poot, D.H.J. (author), Ekinci, Melek (author), Kotek, Gyula (author), van Veldhoven, Peter L.J. (author), Klein, S. (author), Verhaar, Jan A.N. (author), Krestin, Gabriel P. (author), Bierma-Zeinstra, Sita M.A. (author), van Middelkoop, Marienke (author), Oei, Edwin H.G. (author)
Background: Altered perfusion might play an important role in the pathophysiology of patellofemoral pain (PFP), a common knee complaint with unclear pathophysiology. Purpose: To investigate differences in dynamic contrast-enhanced (DCE)-MRI perfusion parameters between patients with PFP and healthy control subjects. Population/Subjects...
journal article 2018
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Sun, Wei (author), Poot, D.H.J. (author), Smal, Ihor (author), Yang, Xuan (author), Niessen, W.J. (author), Klein, S. (author)
Image registration is typically formulated as an optimization process, which aims to find the optimal transformation parameters of a given transformation model by minimizing a cost function. Local minima may exist in the optimization landscape, which could hamper the optimization process. To eliminate local minima, smoothing the cost function...
journal article 2017
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Guyader, Jean Marie (author), Huizinga, W. (author), Fortunati, Valerio (author), Poot, D.H.J. (author), Kranenburg, Matthijs Van (author), Veenland, J.F. (author), Paulides, Margarethus M. (author), Niessen, W.J. (author), Klein, S. (author)
In quantitative magnetic resonance imaging (qMRI), quantitative tissue properties can be estimated by fitting a signal model to the voxel intensities of a series of images acquired with different settings. To obtain reliable quantitative measures, it is necessary that the qMRI images are spatially aligned so that a given voxel corresponds in...
conference paper 2016
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Huizinga, W. (author), Poot, D.H.J. (author), Roshchupkin, G. (author), Bron, E. E. (author), Ikram, M. A. (author), Vernooij, M. W. (author), Rueckert, D. (author), Niessen, W.J. (author), Klein, S. (author)
Both normal aging and neurodegenerative diseases such as Alzheimer's disease cause morphological changes of the brain. To better distinguish between normal and abnormal cases, it is necessary to model changes in brain morphology owing to normal aging. To this end, we developed a method for analyzing and visualizing these changes for the...
conference paper 2016
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