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The Simultaneous Model-Based Estimation of Joint, Muscle, and Tendon Stiffness is Highly Sensitive to the Tendon Force-Strain Relationship

Cop, Christopher P. (author), Jakubowski, Kristen L. (author), Schouten, A.C. (author), Koopman, Bart (author), Perreault, Eric J. (author), Sartori, Massimo (author)

Objective: Accurate estimation of stiffness across anatomical levels (i.e., joint, muscle, and tendon) in vivo has long been a challenge in biomechanics. Recent advances in electromyography (EMG)-driven musculoskeletal modeling have allowed the non-invasive estimation of stiffness during dynamic joint rotations. Nevertheless, validation has...

journal article 2024

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Biomechanical characteristics of rib fracture fixation systems

Prins, Jonne T.H. (author), Van Wijck, Suzanne F.M. (author), Leeflang, M.A. (author), Kleinrensink, Gert Jan (author), Lottenberg, Lawrence (author), de la Santa Barajas, Pablo Moreno (author), Van Huijstee, Pieter J. (author), Vermeulen, Jefrey (author), Verhofstad, Michael H.J. (author), Zadpoor, A.A. (author), Wijffels, Mathieu M.E. (author), Van Lieshout, Esther M.M. (author)

Background: The primary aim of this study was to determine and compare the biomechanical properties of a fractured or intact rib after implant fixation on an embalmed thorax. Methods: Five systems were fixated on the bilateral fractured or intact (randomly allocated) 6th to 10th rib of five post-mortem embalmed human specimens. Each rib...

journal article 2023

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System identification: a feasible, reliable and valid way to quantify upper limb motor impairments

van de Ruit, M.L. (author), van der Velden, Levinia L. (author), Onneweer, Bram (author), Benner, Joyce L. (author), Haarman, Claudia J.W. (author), Ribbers, G.M. (author), Selles, R.W. (author)

Background: Upper limb impairments in a hemiparetic arm are clinically quantified by well-established clinical scales, known to suffer poor validity, reliability, and sensitivity. Alternatively, robotics can assess motor impairments by characterizing joint dynamics through system identification. In this study, we establish the merits of...

journal article 2023

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Current models to understand the onset and progression of scoliotic deformities in adolescent idiopathic scoliosis: a systematic review

Meiring, A. R. (author), de Kater, E.P. (author), Stadhouder, A. (author), van Royen, B. J. (author), Breedveld, P. (author), Smit, T. H. (author)

Purpose: To create an updated and comprehensive overview of the modeling studies that have been done to understand the mechanics underlying deformities of adolescent idiopathic scoliosis (AIS), to predict the risk of curve progression and thereby substantiate etiopathogenetic theories. Methods: In this systematic review, an online search in...

review 2023

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Lessons from natural flight for aviation: then, now and tomorrow

Harvey, Christina (author), de Croon, G.C.H.E. (author), Taylor, Graham K. (author), Bomphrey, Richard J. (author)

Powered flight was once a capability limited only to animals, but by identifying useful attributes of animal flight and building on these with technological advances, engineers have pushed the frontiers of flight beyond our predecessors’ wildest imaginations. Yet, there remain many key characteristics of biological flight that elude current...

journal article 2023

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Osteoarthritis year in review 2021: mechanics

Harlaar, J. (author), Macri, E.M. (author), Wesseling, M.G.H. (author)

Osteoarthritis (OA) has a complex, heterogeneous and only partly understood etiology. There is a definite role of joint cartilage pathomechanics in originating and progressing of the disease. Although it is still not identified precisely enough to design or select targeted treatments, the progress of this year's research demonstrates that...

review 2022

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The Amsterdam Foot Model: a clinically informed multi-segment foot model developed to minimize measurement errors in foot kinematics

Schallig, Wouter (author), van den Noort, Josien C. (author), Piening, Marjolein (author), Streekstra, Geert J. (author), Maas, Mario (author), van der Krogt, Marjolein M. (author), Harlaar, J. (author)

Background: Foot and ankle joint kinematics are measured during clinical gait analyses with marker-based multi-segment foot models. To improve on existing models, measurement errors due to soft tissue artifacts (STAs) and marker misplacements should be reduced. Therefore, the aim of this study is to define a clinically informed, universally...

journal article 2022

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Biomechanics Aware Collaborative Robot System for Delivery of Safe Physical Therapy in Shoulder Rehabilitation

Prendergast, J.M. (author), Balvert, Stephan (author), Driessen, Tom (author), Seth, A. (author), Peternel, L. (author)

In this work, we explore using computational musculoskeletal modeling to equip an industrial collaborative robot with awareness of the internal state of a patient to safely deliver physical therapy. A major concern of robot-mediated physical therapy is that robots may unwittingly injure patients. For patients with shoulder injuries this...

journal article 2021

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Estimation of the modulation of friction from the mechanical impedance variations

Huloux, Nicolas (author), Bernard, Corentin (author), Wiertlewski, M. (author)

Ultrasonic surface-haptic touchscreens produce compelling tactile sensations directly on the users' fingertips. The tactile sensations stem from the modulation of friction produced by acoustic radiation pressure, which reduces the contact between the skin and the glass plate. During this process, some of the vibrations are partly absorbed by...

journal article 2021

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A most painful knee does not induce interlimb differences in knee and hip moments during gait in patients with knee osteoarthritis

Bakker, Nienke F. (author), Schrijvers, Jim C. (author), van den Noort, Josien C. (author), Hall, Michelle (author), van der Krogt, Marjolein M. (author), Harlaar, J. (author), van der Esch, Martin (author)

Background: Patients with knee osteoarthritis can adapt their gait to unload the most painful knee joint in order to try to reduce pain and improve physical function. However, these gait adaptations can cause higher loads on the contralateral joints. The aim of the study was to investigate the interlimb differences in knee and hip frontal...

journal article 2021

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Fixation effects of different types of cannulated screws on vertical femoral neck fracture: A finite element analysis and experimental study

Zhan, Shi (author), Jiang, Dajun (author), Ling, Ming (author), Ding, Jian (author), Yang, Kai (author), Duan, Lei (author), Tsai, Tsung Yuan (author), Feng, Yong (author), van Trigt, B. (author), Jia, Weitao (author), Zhang, Changqing (author), Hu, Hai (author)

Femoral neck fractures (FNFs) in young patients usually result from high-energy violence, and the vertical transcervical type is typically challenging for its instability. FNFs are commonly treated with three cannulated screws (CS), but the role of screws type on fixation effects (FE) is unclear. The purpose of this study was to evaluate the...

journal article 2021

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Unifying system identification and biomechanical formulations for the estimation of muscle, tendon and joint stiffness during human movement

Cop, Christopher P. (author), Cavallo, Gaia (author), van'T Veld, Ronald C. (author), Koopman, Bart F.J.M. (author), Lataire, John (author), Schouten, A.C. (author), Sartori, Massimo (author)

In vivo joint stiffness estimation during time-varying conditions remains an open challenge. Multiple communities, e.g. system identification and biomechanics, have tackled the problem from different perspectives and using different methods, each of which entailing advantages and limitations, often complementary. System identification...

review 2021

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An anthropomorphic deformable phantom of the vaginal wall and cavity

Somerwil, P.C. (author), Nout, Remi A. (author), Mens, Jan Willem M. (author), Kolkman-Deurloo, Inger Karine K. (author), Van Beekhuizen, Heleen J. (author), Dankelman, J. (author), van de Berg, N.J. (author)

Brachytherapy is a common treatment in cervical, uterine and vaginal cancer management. The technique is characterised by rapid developments in the fields of medical imaging, dosimetry planning and personalised medical device design. To reduce unnecessary burden on patients, assessments and training of these technologies should preferable be...

journal article 2021

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Initial contact shapes the perception of friction

Willemet, L. (author), Kanzari, Khoubeib (author), Monnoyer, Jocelyn (author), Birznieks, Ingvars (author), Wiertlewski, M. (author)

Humans efficiently estimate the grip force necessary to lift a variety of objects, including slippery ones. The regulation of grip force starts with the initial contact and takes into account the surface properties, such as friction. This estimation of the frictional strength has been shown to depend critically on cutaneous information....

journal article 2021

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How to measure the area of real contact of skin on glass

Huloux, Nicolas (author), Willemet, L. (author), Wiertlewski, M. (author)

The contact between the fingertip and an object is formed by a collection of micro-scale junctions, which collectively constitute the real contact area. This real area of contact is only a fraction of the apparent area of contact and is directly linked to the frictional strength of the contact (i.e., the lateral force at which the finger...

journal article 2021

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Compensation due to age-related decline in sit-to-stand and sit-to-walk

van der Kruk, E. (author), Silverman, Anne K. (author), Reilly, Peter (author), Bull, Anthony M.J. (author)

Capacity is the physiological ability of the neuromusculoskeletal systems; this declines with age. This decline in capacity may result in the inability to stand up (sit-to-stand, sit-to-walk), which is an important movement for independent living. Compensation, as a result of functional redundancy, is key in understanding how much age-related...

review 2021

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Neuromechanical assessment of knee joint instability during perturbed gait in patients with knee osteoarthritis

Schrijvers, Jim C. (author), van den Noort, Josien C. (author), van der Esch, Martin (author), Harlaar, J. (author)

Knee joint instability is frequently reported by patients with knee osteoarthritis (KOA). Objective metrics to assess knee joint instability are lacking, making it difficult to target therapies aiming to improve stability. Therefore, the aim of this study was to compare responses in neuromechanics to perturbations during gait in patients with...

journal article 2021

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Agent-based mathematical modeling of pancreatic cancer growth and several therapies

Chen, J. (author)

Cancer is known as one of the leading causes of death in the world with difficult<br/>diagnose at early stages, poor prognosis and high mortality. Animal-based<br/>experiments and clinical trials have always been the main approach for cancer<br/>research, albeit they may have limitations and ethical issues. Mathematicalmodeling<br/>as an...

doctoral thesis 2020

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The Human Body Model versus conventional gait models for kinematic gait analysis in children with cerebral palsy

Flux, E. (author), van der Krogt, M. M. (author), Cappa, P. (author), Petrarca, M. (author), Desloovere, K. (author), Harlaar, J. (author)

With the rise of biofeedback in gait training in cerebral palsy there is a need for real-time measurements of gait kinematics. The Human Body Model (HBM) is a recently developed model, optimized for the real-time computing of kinematics. This study evaluated differences between HBM and two commonly used models for clinical gait analysis: the...

journal article 2020

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Technical note: a novel servo-driven dual-roller handrim wheelchair ergometer

De Klerk, R. (author), Vegter, R. J.K. (author), Veeger, H.E.J. (author), van der Woude, L.H.V. (author)

The measurement of handrim wheelchair propulsion characteristics and performance in the field is complicated due to the non-stationary nature of wheelchair driving. In contrast, the laboratory provides a constrained and standardisable environment to conduct measurements and experiments. Apart from wheelchair treadmills, dynamometers or...

journal article 2020