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A Geant4 based simulation platform of the HollandPTC R&D proton beamline for radiobiological studiesGroenendijk, C.F. (author), Rovituso, M. (author), Lathouwers, D. (author), Brown, J.M.C. (author)A Geant4 based simulation platform of the Holland Proton Therapy Centre (HollandPTC, Netherlands) R&D beamline (G4HPTC-R&D) was developed to enable the planning, optimisation and advanced dosimetry for radiobiological studies. It implemented a six parameter non-symmetrical Gaussian pencil beam surrogate model to simulate the R&D...journal article 2023
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Brown, J.M.C. (author), Hanna, Gerard G. (author), Lampe, Nathanael (author), Villagomez-Bernabe, Balder (author), Nicol, James R. (author), Coulter, Jonathan A. (author), Currell, Fred J. (author)A novel treatment planning framework, the Relative Biological Effective Dose (RBED), for high Z nanoparticle (NP)-enhanced photon radiotherapy is developed and tested in silico for the medical exemplar of neoadjuvant (preoperative) breast cancer MV photon radiotherapy. Two different treatment scenarios, conventional and high Z NP enhanced,...journal article 2018