A review on machine learning in flexible surgical and interventional robots: Where we are and where we are going

Minimally Invasive Procedures (MIPs) emerged as an alternative to more invasive surgical approaches, offering patient benefits such as smaller incisions, less pain, and shorter hospital stay. In one class of MIPs, where natural body lumens or small incisions are used to access deeper anatomical locations, Flexible Surgical and Interventional...

Current models to understand the onset and progression of scoliotic deformities in adolescent idiopathic scoliosis: a systematic review

Purpose: To create an updated and comprehensive overview of the modeling studies that have been done to understand the mechanics underlying deformities of adolescent idiopathic scoliosis (AIS), to predict the risk of curve progression and thereby substantiate etiopathogenetic theories. Methods: In this systematic review, an online search in...

Model-based optimization approaches for pressure-driven membrane systems

Membrane technology is commonly used within food, bio- and pharmaceutical processes. Beside single-stage membranes, multi-stage membrane systems are become more popular to improve separation performance. In this review, we present a unified four-phase model-based optimization framework to optimize these systems, using mechanistic models,...

Modeling cell–cell communication for immune systems across space and time

Communicating is crucial for cells to coordinate their behaviors. Immunological processes, involving diverse cytokines and cell types, are ideal for developing frameworks for modeling coordinated behaviors of cells. Here, we review recent studies that combine modeling and experiments to reveal how immune systems use autocrine, paracrine, and...