Risk-based optimization of emergency response systems for accidental gas leakage in utility tunnels

Focusing on the effective configuration of emergency response systems in utility tunnels, this study proposes an innovative approach to optimize existing emergency response systems based on a consequence rapid prediction model and genetic algorithm. In the proposed approach, the interactions between different emergency response components are...

BI-IEnKF coupling model for effective source term estimation of natural gas leakage in urban utility tunnels

As an effective way to facilitate the increasing demand for reliable infrastructure, energy supply and sustainable urban development, underground utility tunnels have been developed rapidly in recent years. Due to the widespread distribution of utility tunnels, the safe operation of natural gas pipelines accommodated in utility tunnels has...

Structure-Based Redesign of a Methanol Oxidase into an “Aryl Alcohol Oxidase” for Enzymatic Synthesis of Aromatic Flavor Compounds

Alcohol oxidases (AOxs) catalyze the aerobic oxidation of alcohols to the corresponding carbonyl products (aldehydes or ketones), producing only H₂O₂ as the byproduct. The majority of known AOxs, however, have a strong preference for small, primary alcohols, limiting their broad applicability, e.g., in the food industry....

A conflict cluster-based method for collision avoidance decision-making in multi-ship encounter situations

During the process of collision avoidance, especially in a multi-ship encounter situation, the dynamic interactions among individual ships impose a significant impact on collision avoidance decision-making. It is imperative, therefore, that collision avoidance decisions are formulated with a comprehensive consideration of not only the current...

Safety barriers in the chemical process industries: A state-of-the-art review on their classification, assessment, and management

Barriers are used in various forms to assure the safety of chemical plants. A deep understanding of the literature related to safety barriers is essential to tackle the challenges in improving their design and management. This paper first provides an overview of the history of the development of the safety barrier concept. Subsequently, this...

A comprehensive review on the prediction of ship energy consumption and pollution gas emissions

Ship energy consumption and emission prediction are critical for ship energy efficiency management and pollution gas emission control, both of which are major concerns for the shipping industry and hence continue to attract global attention and research interest. This article examined the energy efficiency data sources, big data analysis for...

Safety barrier performance assessment by integrating computational fluid dynamics and evacuation modeling for toxic gas leakage scenarios

Toxic gas leakage represents a type of major process accident scenario threatening human life. Technical and non-technical safety barriers are employed to prevent toxic gas leakage accidents or mitigate the possible catastrophic consequences. Evacuation must be executed in severe toxic gas release scenarios. The performance assessment of...

Dynamic resilience assessment and emergency strategy optimization of natural gas compartments in utility tunnels

As a kind of critical infrastructure of energy transportation, so-called ‘utility tunnels’ have been developed around the world. Hosting a natural gas pipeline inside the natural gas compartment of a utility tunnel facilitates its maintenance but also brings potential explosion concerns due to the confined space. Although some work focuses on...

Prediction of gas leakage and dispersion in utility tunnels based on CFD-EnKF coupling model: A 3D full-scale application

Natural gas compartment accommodated in utility tunnels is beneficial in meeting the pressing demand of energy supply and sustainable urban environment. However, the leaking gas characterized by flammable and explosive can pose a huge threat to the safe operation of the utility tunnel. When an unexpected gas leakage accident happens in the...

A Biocatalytic Platform for the Synthesis of Enantiopure Propargylic Alcohols and Amines

Propargylic alcohols and amines are versatile building blocks in organic synthesis. We demonstrate a straightforward enzymatic cascade to synthesize enantiomerically pure propargylic alcohols and amines from readily available racemic starting materials. In the first step, the peroxygenase from Agrocybe aegerita converted the racemic...

Graph Convolution-Based Deep Reinforcement Learning for Multi-Agent Decision-Making in Interactive Traffic Scenarios

A reliable multi-agent decision-making system is highly demanded for safe and efficient operations of connected and autonomous vehicles (CAVs). In order to represent the mutual effects between vehicles and model the dynamic traffic environments, this research proposes an integrated and open-source framework to realize different Graph...

Unravelling key factors controlling vivianite formation during anaerobic digestion of waste activated sludge

As a product of phosphorous recovery from anaerobic digestion (AD) of waste activated sludge (WAS), vivianite has received increasing attention. However, key factors controlling vivianite formation have not yet been fully addressed. Thus, this study was initiated to ascertain key factors controlling vivianite formation. A simulation of...

Risk assessment of large-scale winter sports sites in the context of a natural disaster

Accidents induced by natural disasters at sports sites may cause catastrophic loss of great concern. However, previous studies on risk assessments of sports sites have only focused on operational risk and equipment failure. With the frequent occurrence of extreme disasters, the risk of domino chains caused by natural disasters at large-scale...

Investigation of the Rheological Properties and Chemical Structure of Asphalt under Multiple Aging Conditions of Heat, UV and Aqueous Solution

During the service period, asphalt materials are affected by various natural factors, including heat, ultraviolet light, oxygen and moisture, etc., resulting in the reduction of pavement performance, the increase of pavement distress and shortening of service life. This study aims to investigate the aging performance of asphalt under multiple...

Fresh and hardened properties of self-compacting concrete containing recycled fine clay brick aggregates

Clay brick is one of the major components of demolition waste, which is generally landfilled. Effective and new uses of recycled clay brick may provide sustainability benefits in terms of landfill reduction. Therefore, this research aims at applying Recycled fine clay brick aggregates (RFCBA) with sizes from 0.075 mm–4.75 mm to prepare Self...

Numerical analysis of multi-factors effects on the leakage and gas diffusion of gas drainage pipeline in underground coal mines

Gas drainage system is a critical technique to prevent gas outbursts in the underground coal mine. The leakage of gas drainage pipelines can pose serious threats to the safety production of underground mining. In this paper, a multi-factors gas drainage pipeline leakage and diffusion (GDPLD) model is proposed based on the OpenFOAM platform,...

CFD and EnKF coupling estimation of LNG leakage and dispersion

As a kind of clean fuel, increasing quantities of natural gas have been transported as liquefied natural gas (LNG) worldwide. The safety of LNG storage has gained the concerns from the public due to the potential severe consequences that may arise from LNG leakage. In this paper, a three-dimensional model with the combination of computational...

Engineered Tumor Cell Apoptosis Monitoring Method Based on Dynamic Laser Tweezers

Monitoring the cells’ apoptosis progression could provide a valuable insight into the temporal events that initiate cell death as well as the potential for rescue of apoptotic cells. In this paper, we engineered a novel and robust method for monitoring apoptosis of tumor cells based on dynamic laser tweezers, using A549 and HeLa cell line as...