- document
-
Mirzaali, Mohammad J. (author), Shahriari, N.S. (author), Zhou, J. (author), Zadpoor, A.A. (author)Additive manufacturing (AM) technologies, particularly those based on powder bed fusion (PBF), most notably, selective laser melting (SLM) for metals, have in recent years emerged as unique fabrication methods for patient-specific implants made of metals and their alloys. The ability to manufacture complex geometries together with the other...book chapter 2023
- document
-
Zadpoor, A.A. (author), Mirzaali, Mohammad J. (author), Valdevit, Lorenzo (author), Hopkins, Jonathan B. (author)Metamaterials are engineered materials with unusual, unique properties and advanced functionalities that are a direct consequence of their microarchitecture. While initial properties and functionalities were limited to optics and electromagnetism, many novel categories of metamaterials that have applications in many different areas of...contribution to periodical 2023
- document
-
Dimaraki, A. (author), Diaz Payno, P.J. (author), Minneboo, M.B. (author), Nouri Goushki, M. (author), Hosseini, M. (author), Kops, N. (author), Narcisi, R. (author), Mirzaali, Mohammad J. (author), van Osch, G.J.V.M. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)The treatment of articular cartilage defects remains a significant clinical challenge. This is partially due to current tissue engineering strategies failing to recapitulate native organization. Articular cartilage is a graded tissue with three layers exhibiting different cell densities: the superficial zone having the highest density and the...journal article 2021
- document
-
Naghavi Zadeh, S.M. (author), Alijani, F. (author), Chen, X. (author), Dayyani, Iman (author), Yasaee, Mehdi (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Mechanical metamaterials are advanced engineering materials that exhibit unusual properties that cannot be found in nature. The elastic properties (i.e., elastic modulus and Poisson's ratio) of mechanical metamaterials can be tuned by changing the geometry of their fundamental unit cells. This allows for the design of metamaterial lattices...journal article 2021
- document
-
Mirzaali, Mohammad J. (author), Janbaz, S. (author), Strano, M. (author), Vergani, L. (author), Zadpoor, A.A. (author)Architectured materials with rationally designed geometries could be used to create mechanical metamaterials with unprecedented or rare properties and functionalities. Here, we introduce "shape-matching" metamaterials where the geometry of cellular structures comprising auxetic and conventional unit cells is designed so as to achieve a pre...journal article 2018
- document
-
Isaakidou, A. (author), Ganjian, M. (author), van Hoften, R. (author), Cruz Saldivar, M. (author), Leeflang, M.A. (author), Groetsch, A. (author), Wątroba, M. (author), Schwiedrzik, J. (author), Mirzaali, Mohammad J. (author), Apachitei, I. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)The currently available treatments for inner ear disorders often involve systemic drug administration, leading to suboptimal drug concentrations and side effects. Cochlear implants offer a potential solution by providing localized and sustained drug delivery to the cochlea. While the mechanical characterization of both the implants and their...journal article 2024
- document
-
Deep Learning for Size-Agnostic Inverse Design of Random-Network 3D Printed Mechanical MetamaterialsPahlavani, H. (author), Tsifoutis-Kazolis, Kostas (author), Cruz Saldivar, M. (author), Mody, Prerak (author), Zhou, J. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Practical applications of mechanical metamaterials often involve solving inverse problems aimed at finding microarchitectures that give rise to certain properties. The limited resolution of additive manufacturing techniques often requires solving such inverse problems for specific specimen sizes. Moreover, the candidate microarchitectures...journal article 2023
- document
-
Yu, K. (author), Balasubramanian, S. (author), Pahlavani, H. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author), Aubin-Tam, M.E. (author)Natural materials, such as nacre and silk, exhibit both high strength and toughness due to their hierarchical structures highly organized at the nano-, micro-, and macroscales. Bacterial cellulose (BC) presents a hierarchical fibril structure at the nanoscale. At the microscale, however, BC nanofibers are distributed randomly. Here, BC self...journal article 2020
- document
-
Nouri Goushki, M. (author), Angeloni, L. (author), Modaresifar, K. (author), Minneboo, M.B. (author), Boukany, P. (author), Mirzaali, Mohammad J. (author), Ghatkesar, M.K. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)The surface topography of implantable devices is of crucial importance for guiding the cascade of events that starts from the initial contact of the cells with the surface and continues until the complete integration of the device in its immediate environment. There is, however, limited quantitative information available regarding the...journal article 2021
- document
-
Mirzaali, Mohammad J. (author), Ghorbani, Aref (author), Nakatani, Kenichi (author), Nouri Goushki, M. (author), Tümer, N. (author), Callens, S.J.P. (author), Janbaz, S. (author), Accardo, A. (author), Bico, José (author), Habibi, Mehdi (author), Zadpoor, A.A. (author)The design of advanced functional devices often requires the use of intrinsically curved geometries that belong to the realm of non-Euclidean geometry and remain a challenge for traditional engineering approaches. Here, it is shown how the simple deflection of thick meta-plates based on hexagonal cellular mesostructures can be used to achieve...journal article 2021
- document
-
Oldhoff, M. G.E. (author), Mirzaali, Mohammad J. (author), Tümer, N. (author), Zhou, J. (author), Zadpoor, A.A. (author)Additive manufacturing (AM) offers great design freedom that enables objects with desired unique and complex geometry and topology to be readily and cost-effectively fabricated. The overall benefits of AM are well known, such as increased material and resource efficiency, enhanced design and production flexibility, the ability to create...journal article 2021
- document
-
Kolken, H.M.A. (author), Garcia, A. Fontecha (author), Plessis, A. Du (author), Meynen, A. (author), Rans, C.D. (author), Scheys, L. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)The fatigue performance of additively manufactured auxetic meta-biomaterials made from commercially pure titanium has been studied only recently. While certain assumptions have been made regarding the mechanisms underlying their fatigue failure, the exact mechanisms are not researched yet. Here, we studied the mechanisms of crack formation...journal article 2022
- document
-
Nouri Goushki, M. (author), Isaakidou, A. (author), Eijkel, B.I.M. (author), Minneboo, M.B. (author), Liu, Q. (author), Boukany, P. (author), Mirzaali, Mohammad J. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)The surface topography of engineered extracellular matrices is one of the most important physical cues regulating the phenotypic polarization of macrophages. However, not much is known about the ways through which submicron (i.e., 100-1000 nm) topographies modulate the polarization of macrophages. In the context of bone tissue regeneration,...journal article 2021
- document
-
Pahlavani, H. (author), Amani, M. (author), Cruz Saldivar, M. (author), Zhou, J. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Emerging multi-material 3D printing techniques enables the rational design of metamaterials with not only complex geometries but also arbitrary distributions of multiple materials within those geometries, yielding unique combinations of elastic properties. However, discovering the rare designs that lead to highly unusual combinations of...journal article 2022
- document
-
Kubo, Yusuke (author), Beckmann, Rainer (author), Pahlavani, H. (author), Cruz Saldivar, M. (author), Szymanski, Katharina (author), Leeflang, M.A. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author), Wruck, Christoph Jan (author), Jahr, H. (author)Background: Nuclear factor erythroid 2–related factor 2 (Nrf2) is a crucial transcription factor for cellular redox homeostasis. The association of Nrf2 with elderly female osteoporotic has yet to be fully described. The aim was to elucidate a potential age-dependent Nrf2 contribution to female osteoporosis in mice. Methods: Eighteen female...journal article 2022
- document
-
Kolken, H.M.A. (author), Callens, S.J.P. (author), Leeflang, M.A. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)The rational design of bone-substituting biomaterials is relatively complex because they should meet a long list of requirements for optimal performance. Meta-biomaterials are micro-architected materials that hold great promise for meeting those requirements as they offer a unique combination of mechanical, mass-transport, and biological...journal article 2022
- document
-
Yang, J. (author), Chen, Xiaohong (author), Sun, Yuanxi (author), Feng, Chen (author), Yang, Zheng (author), Zadpoor, A.A. (author), Mirzaali, Mohammad J. (author), Bai, Long (author)The advent of additive manufacturing has facilitated the design and fabrication of hybrid lattice structures with multiple morphologies. These structures combine multiple distinct architectures into a single structure with an exceptional performance that far exceeds that of each constituting architecture. However, combining strut-based...journal article 2023
- document
-
de Jong, P.H. (author), Salvatori, Y.S. (author), Libonati, F. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Shape morphing is the ability of objects to adapt to different shapes and reduce stress concentrations through increased contact area. This is a common trait of natural and engineered objects and has several applications in, among others, soft robotics and orthopedic implants. Shape morphing is achieved through flexible materials or rigid...journal article 2023
- document
-
Moosabeiki, Vahid (author), Yarali, E. (author), Ghalayaniesfahani, A. (author), Callens, S.J.P. (author), van Manen, T. (author), Accardo, A. (author), Ghodrat, S. (author), Bico, José (author), Habibi, Mehdi (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Emerging 4D printing techniques have enabled the realization of smart materials whose shape or properties can change with time. Two important phenomena play important roles in the 4D printing of shape memory polymeric materials. First, the anisotropic deformation of the printed filaments due to residual stresses can be harnessed to create out...journal article 2024
- document
-
Kolken, H.M.A. (author), Garcia, A. Fontecha (author), Du Plessis, A. (author), Rans, C.D. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Meta-biomaterials offer a promising route towards the development of life-lasting implants. The concept aims to achieve solutions that are ordinarily impossible, by offering a unique combination of mechanical, mass transport, and biological properties through the optimization of their small-scale geometrical and topological designs. In this...journal article 2021