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Brown, Michael D. (author), Generowicz, Bastian S. (author), Dijkhuizen, Stephanie (author), Koekkoek, Sebastiaan K.E. (author), Strydis, C. (author), Bosch, Johannes G. (author), Arvanitis, Petros (author), Springeling, Geert (author), Leus, G.J.T. (author), De Zeeuw, Chris I. (author), Kruizinga, P. (author)Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), an imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction...journal article 2024
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Simoes dos Santos, D. (author), Ossenkoppele, B.W. (author), Hopf, Y.M. (author), Soozande, Mehdi (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), de Jong, N. (author)Objective: Described here is the development of an ultrasound matrix transducer prototype for high-frame-rate 3-D intra-cardiac echocardiography. Methods: The matrix array consists of 16 × 18 lead zirconate titanate elements with a pitch of 160 µm × 160 µm built on top of an application-specific integrated circuit that generates transmission...journal article 2024
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Kortenbout, A.J. (author), Costerus, Sophie (author), Dudink, Jeroen (author), de Jong, N. (author), de Graaff, Jurgen C. (author), Vos, H.J. (author), Bosch, Johan G. (author)Objective: Post-operative brain injury in neonates may result from disturbed cerebral perfusion, but accurate peri-operative monitoring is lacking. High-frame-rate (HFR) cerebral ultrasound could visualize and quantify flow in all detectable vessels using spectral Doppler; however, automated quantification in small vessels is challenging...journal article 2024
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Pelka, S. (author), Bosch, A. (author), Chappin, E.J.L. (author), Liesenhoff, F. (author), Kühnbach, M. (author), De Vries, Laurens (author)Electric vehicle (EV) users who aim to become flexibility providers face a tradeoff between staying in control of charging and minimizing their electricity costs. The common practice is to charge immediately after plugging in and use more electricity than necessary. Changing this can increase the EV’s flexibility potential and reduce...journal article 2024
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van der Meulen, P.Q. (author), Coutino, Mario (author), Bosch, Johannes G. (author), Kruizinga, P. (author), Leus, G.J.T. (author)We consider the scenario of finding the transfer function of an aberrating layer in front of a receiving ultrasound (US) array, assuming a separate non-aberrated transmit source. We propose a method for blindly estimating this transfer function without exact knowledge of the ultrasound sources or acoustic contrast image, and without directly...journal article 2023
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Guo, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J. G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)This paper presents a pitch-matched transceiver ASIC integrated with a 2-D transducer array for a wearable ultrasound device for transfontanelle ultrasonography. The ASIC combines 8-fold multiplexing, 4-channel micro-beamforming (μ BF) and sub-array-level digitization to achieve a 128-fold channel-count reduction. The μ BF is based on passive...conference paper 2023
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Wu, X. (author), Saaid, Hicham (author), Voorneveld, J.D. (author), Claessens, Tom (author), Westenberg, Jos J.M. (author), de Jong, N. (author), Bosch, Johan G. (author), Kenjeres, S. (author)Purpose: Intraventricular blood flow dynamics are associated with cardiac function. Accurate, noninvasive, and easy assessments of hemodynamic quantities (such as velocity, vortex, and pressure) could be an important addition to the clinical diagnosis and treatment of heart diseases. However, the complex time-varying flow brings many...journal article 2023
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Caenen, Annette (author), Keijzer, Lana (author), Bézy, Stéphanie (author), Duchenne, Jürgen (author), Orlowska, Marta (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bosch, Johan G. (author), Voigt, Jens Uwe (author), D’hooge, Jan (author), Vos, H.J. (author)Ultrasound-based shear wave elastography is a promising technique to non-invasively assess the dynamic stiffness variations of the heart. The technique is based on tracking the propagation of acoustically induced shear waves in the myocardium of which the propagation speed is linked to tissue stiffness. This measurement is repeated multiple...journal article 2023
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Hu, Yuyang (author), Doğan, D. (author), Brown, Michael (author), Bulot, Mahé (author), Ferin, Guillaume (author), Leus, G.J.T. (author), Kruizinga, P. (author), Steen, Antonius F.W. (author), Bosch, Johannes G. (author)It has been previously demonstrated that applying an aberrating mask for 2D compressive imaging using a low number of sensors (elements) can significantly improve image resolution, as evaluated via the point spread function. Here we investigate the potential to apply a similar approach for 3D flow monitoring. We conducted a 3D k-Wave simulation...conference paper 2023
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Guo, P. (author), Fool, F. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)This article presents a low-power and small-area transceiver application-specific integrated circuit (ASIC) for 3-D trans-fontanelle ultrasonography. A novel micro-beamforming receiver architecture that employs current-mode summation and boxcar integration is used to realize delay-and-sum on an N -element sub-array using N× fewer capacitive...journal article 2023
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Spiekhout, Sander (author), Voorneveld, J.D. (author), Van Elburg, Benjamin (author), Renaud, G.G.J. (author), Segers, Tim (author), Lajoinie, Guillaume P.R. (author), Versluis, Michel (author), Verweij, M.D. (author), de Jong, N. (author), Bosch, Johannes G. (author)Ultrasound (US) contrast agents consist of microbubbles ranging from 1 to 10 μm in size. The acoustical response of individual microbubbles can be studied with high-frame-rate optics or an "acoustical camera"(AC). The AC measures the relative microbubble oscillation while the optical camera measures the absolute oscillation. In this article,...journal article 2022
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Hopf, Y.M. (author), Ossenkoppele, Boudewine W. (author), Soozande, Mehdi (author), Noothout, E.C. (author), Chang, Z.Y. (author), Chen, Chao (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)In this article, an application-specific integrated circuit (ASIC) for 3-D, high-frame-rate ultrasound imaging probes is presented. The design is the first to combine element-level, high-voltage (HV) transmitters and analog front-ends, subarray beamforming, and in-probe digitization in a scalable fashion for catheter-based probes. The...journal article 2022
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Guo, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)This article presents a compact analog front-end (AFE) circuit for ultrasound receivers with linear-in-dB continuous gain control for time-gain compensation (TGC). The AFE consists of two variable-gain stages, both of which employ a novel complementary current-steering network (CCSN) as the interpolator to realize continuously variable gain....journal article 2022
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Hopf, Y.M. (author), Ossenkoppele, B.W. (author), Soozande, M. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)In this letter, a compact high-voltage (HV) transmit circuit for dense 2-D transducer arrays used in 3-D ultrasonic imaging systems is presented. Stringent area requirements are addressed by a unipolar pulser with embedded transmit/receive switch. Combined with a capacitive HV level shifter, it forms the ultrasonic HV...journal article 2022
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Soozande, Mehdi (author), Ossenkoppele, B.W. (author), Hopf, Y.M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), de Jong, N. (author), Vos, H.J. (author), Bosch, Johan G. (author)Atrial fibrillation (AF) is the most common cardiac arrhythmia and is normally treated by RF ablation. Intracardiac echography (ICE) is widely employed during RF ablation procedures to guide the electrophysiologist in navigating the ablation catheter, although only 2-D probes are currently clinically used. A 3-D ICE catheter would not only...journal article 2022
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Schoonderwoerd, Tjeerd A.J. (author), van Zoelen, E.M. (author), Bosch, Karel van den (author), Neerincx, M.A. (author)The rapid advancement of technology empowered by artificial intelligence is believed to intensify the collaboration between humans and AI as team partners. Successful collaboration requires partners to learn about each other and about the task. This human-AI co-learning can be achieved by presenting situations that enable partners to share...journal article 2022
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Hu, Yuyang (author), Brown, Michael (author), Doğan, D. (author), Leus, G.J.T. (author), Kruizinga, P. (author), Van Der Steen, Antonius F.W. (author), Bosch, Johannes G. (author)We intend to develop an ultrasound compressive imaging device to perform carotid artery (CA) function and flow monitoring/imaging by using just a few single element transducers equipped with spatial coding masks. The spatially unique impulse responses can be exploited in compressive reconstructions. To explore the potential of different...conference paper 2022
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Simoes dos Santos, D. (author), Fool, F. (author), Kim, Taehoon (author), Noothout, E.C. (author), Rozsa, N.N.M. (author), Vos, H.J. (author), Bosch, Johan G. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), De Jona, Nico (author)Over the past decades, ultrasound imaging has made considerable progress based on the advancement of imaging systems as well as transducer technology. With the need for advanced transducer arrays with complex designs and technical requirements, there is also a need for suitable tools to characterize such transducers. However, despite the...conference paper 2022
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Colas, Quorentin (author), Bantignies, Claire (author), Perroteau, Marie (author), Porcher, Nicolas (author), Vassal, Steeven (author), Bosch, Johan G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)Three-dimensional ultrasound has initially been used to address volumetric imaging for diagnostic purposes and represents the leading-edge technological orientation in both transducer and IC (integrated circuit) architecture and design. However, new applications are coming up like biomarker measurements, preoperative navigation, real time...conference paper 2022
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Simoes dos Santos, D. (author), Fool, F. (author), Mozaffarzadeh, M. (author), Shabanimotlagh, M. (author), Noothout, E.C. (author), Kim, T. (author), Rozsa, N.N.M. (author), Vos, H.J. (author), Bosch, Johan G. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), de Jong, N. (author)High frame rate three-dimensional (3D) ultrasound imaging would offer excellent possibilities for the accurate assessment of carotid artery diseases. This calls for a matrix transducer with a large aperture and a vast number of elements. Such a matrix transducer should be interfaced with an application-specific integrated circuit (ASIC) for...journal article 2022