Searched for: contributor%3A%22Reinders%2C+M.J.T.+%28mentor%29%22
(21 - 40 of 41)

Pages

document
Pourquié, Valérie (author)
Human brain research is advancing, facilitated by improved high-throughput techniques and systematically preservation of brain tissue in brain banks. Due to the complex organization and regulation of the brain, most studies only focus on a single aspect of healthy and diseased samples. This research integrates analyses of the transcriptome and...
master thesis 2019
document
Klaassen, Matthijs (author)
In this paper we investigate 4 different methods to predict protein sub cellular location using protein interaction networks. We present a very simple algorithm as a benchmark to which the other, more complex, methods can be measured. This algorithm is based on the simple observation that to interact proteins must be physically close to one...
bachelor thesis 2019
document
Hoogenboom, Iwan (author)
Determining protein subcellular location is important for understanding cellular<br/>functions and biological processes of underlying diseases. High throughput fluorescence images can be used in combination with convolutional neural networks to predict this location. In this work we propose a hierarchical model which uses prior knowledge of...
bachelor thesis 2019
document
Wen, Xiaoming (author)
Optical flow is a representation of projected real-world motion of the object between two consecutive images. The optical flow measures the pixel displacement on the image coordinate plane. However, it does not reveal the motion in depth explicitly, which could be useful as input in some tasks such as vehicle tracking. To extend the original...
master thesis 2018
document
van Dorth, Matthijs (author)
master thesis 2017
document
Makrodimitris, S. (author)
master thesis 2016
document
Van den Bogaerdt, P. (author)
Mutations in ones DNA can influence the risk for developing Alzheimer's disease (Alzheimer). DNA consists of long strings of nucleotides, which together define the genome. However, next to these nucleotides, also the way in which DNA wraps in a cell affects the function of a cell. The information describing the DNA wrapping state is called the...
bachelor thesis 2015
document
Witteveen, M.J. (author)
Motivation: Identification and elucidation of eQTL has long been an active area of research. Finding cis-eQTL has been a manageable problem because of the limited number of candidates. Finding transeQTL has on the other hand been much more challenging because of the issue of multiple hypothesis testing. It has been suggested that additional...
master thesis 2014
document
Yao, Y. (author)
A single-molecule protein sequencer, which labels only 2 out of 20 amino acids and uses single-molecule TIRF microscopy to measure the order of these fingerprints, opens the door to identify proteins with high fidelity using only a small quantity of sample. From the fingerprint, a key challenge is to detect which protein was measured. We present...
master thesis 2014
document
Wu, Y. (author), De Ridder, J. (author), Reinders, M.J.T. (author)
Breast cancer is one of the most prevalent cancers affecting females in the world. In recent years, many cancer researchers have been trying to determine molecular prognosis tools that predict cancer patient treatment response and/or chance of survival. In particular, the determination of gene expression signatures obtained by feature selection...
master thesis 2013
document
Van Beek, D.M. (author)
This report is made as part of the Master's Thesis project of the master Computer Science, track Bioinformatics at the Delft University of technology. The main focus of this document lies on the paper that is written as the result of my research on the detection of copy number variations using next generation sequencing data. In the future it is...
master thesis 2012
document
Straver, R. (author)
Motivation: Numerous genetic disorders can be detected in prenatal diagnosis using Chorionic Villus Sampling. As this brings a 1:100 chance for miscarriage, this method is only applied when the fetus is suspected to have an increased chance at having an aberration. It is known that a small percentage of DNA in maternal plasma is of fetal origin...
master thesis 2012
document
Au, S.T. (author), Lesmana, F. (author), Kuethe, F. (author)
Expansion of an existing visualization tool for genomic data.
bachelor thesis 2012
document
Meijer, R.J. (author)
In this thesis an approximation method is discussed that provides similar results to leave-one-out cross-validation but is less time-consuming. By means of this approximation method, estimating the optimal values of ridge and lasso parameters will take less time and carrying out (an approximated version of) double LOOCV will become practically...
master thesis 2010
document
Van Kouteren, H.J.W. (author)
In this thesis we present the database security mechanism and Web services implementation for the Ibidas system. The security mechanism restricts access to data by source per user. Web services provide an interface to call Ibidas methods and share data from and with other applications. We will see the need for the features presented, how they...
master thesis 2009
document
Sanders, M.A. (author)
Continuous variable selection using shrinkage procedures have recently been considered as favorable models in a wide range of scientific research; in particular biomedical research. In some cases, it is desirable to select as few predictors as possible, to increase the interpretability of the attained prediction rule. One frequently used...
master thesis 2009
document
Karavides, T. (author)
Automated landmark detection may prove important for the examination and automatic analysis of real-time three-dimensional (3D) echocardiograms. By detecting 3D anatomical landmark points, the standard anatomical views can be extracted automatically in 3D ultrasound images of left ventricle, for better standardization and objective diagnosis....
master thesis 2009
document
Van den Berg, B.A. (author)
Motivation: Synthetic biology aims at building biological systems for useful purposes. Relatively simple gene networks have been engineered, but the design process is limited. Many papers advocate the use of engineering concepts like standardization and modular design to simplify the design process and enable the design of more complex systems....
master thesis 2009
document
Van der Leije, M.R. (author)
Unbalanced transaction can lead to addition and deletions in genes, which can be an indication of tumor cells. This is measured with array Comparative Genomic Hybridization. To find co-occurring aberrations in DNA, an algorithm was designed. However the execution takes days to find these DNA aberrations. This thesis proposes a partial FPGA based...
master thesis 2009
document
Wildeman, M.H. (author)
In this project we tried to answer the question whether it is possible to obtain in vivo quantitative spatiotemporal gene expression data of mice, by making use of the GFP protein and Biofluorence Imaging. The research was driven by a more specific question, being whether it is possible to detect if metastasis to the bone has occurred in cancer...
master thesis 2009
Searched for: contributor%3A%22Reinders%2C+M.J.T.+%28mentor%29%22
(21 - 40 of 41)

Pages