Searched for: department%3A%22BT%255C%257Eslsh%257EBiotechnology%22
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Liu, Y. (author), Salemink, H.W.M. (author)
We report the results of a study of an optical sensor based on a channel-drop technique with two cascaded cavities in photonic-crystal slabs. Quality factors and intensities of the resonant modes of the sensor were analyzed with three-dimensional simulations. With the introduction of a reflector in the bus-channel and by control of the coupling...
journal article 2015
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Zhang, J. (author), Ten Pierick, A. (author), Van Rossum, H.M. (author), Maleki Seifar, R. (author), Daran, J.G. (author), Heijnen, J.J. (author), Wahl, S.A. (author)
Eukaryotic metabolism is organised in complex networks of enzyme catalysed reactions which are distributed over different organelles. To quantify the compartmentalised reactions, quantitative measurements of relevant physiological variables in different compartments are needed, especially of cofactors. NADP(H) are critical components in cellular...
journal article 2015
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Mooij, P.R. (author), De Jongh, L.D. (author), Van Loosdrecht, M.C.M. (author), Kleerebezem, R. (author)
Microalgae have the potential to supply a biobased society with essential feedstocks like sugar and lipids. Besides being productive, strains used for this purpose should grow fast, be resistant to predators, and have good harvestability properties. Diatoms, a class of siliceous algae, have these and other preferred characteristics. In this...
journal article 2015
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Heeres, A.S. (author), Schroën, K. (author), Heijnen, J.J. (author), Van der Wielen, L.A.M. (author), Cuellar, M.C. (author)
Developments in synthetic biology enabled the microbial production of long chain hydrocarbons, which can be used as advanced biofuels in aviation or transportation. Currently, these fuels are not economically competitive due to their production costs. The current process offers room for improvement: by utilizing lignocellulosic feedstock,...
journal article 2015
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Vasudevan Srinivasan, V. (author), Ranoux, A. (author), Maheswari, R. (author), Hanefeld, U. (author), Ramanathan, A. (author), Subramaniam, B. (author)
The acidity of Zr-incorporated large pore cubic mesoporous silicate, KIT-5, with Fm3m symmetry was explored as catalyst in the Hantzsch reaction for preparation of 1,4-dihydropyridine (DHP) derivatives, Meerwein–Ponndorf–Verley (MPV) reduction of 4-tert-butylcyclohexanone, and Prins reaction of citronellal. The catalyst showed ~82–94 %...
journal article 2015
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Lin, Y.M. (author), Nierop, K.G.J. (author), Girbal-Neuhauser, E. (author), Adriaanse, M. (author), Van Loosdrecht, M.C.M. (author)
To evaluate the possibility of utilizing polysaccharide-based biomaterial recovered from aerobic granular sludge as a coating material, the morphology, molecular weight distribution and chemical composition of the recovered biomaterial were investigated by atomic force microscopy, size exclusion chromatography and pyrolysis–GC–MS to have a...
journal article 2015
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Evaristo, G.P.C. (author), Pinkse, M.W.H. (author), Chen, T. (author), Wang, L. (author), Mohammed, S. (author), Heck, A.J.R. (author), Mathes, I. (author), Lottspeich, F. (author), Shaw, C. (author), Albar, J.P. (author), Verhaert, P.D.E.M. (author)
An MS/MS based analytical strategy was followed to solve the complete sequence of two new peptides from frog (Odorrana schmackeri) skin secretion. This involved reduction and alkylation with two different alkylating agents followed by high resolution tandem mass spectrometry. De novo sequencing was achieved by complementary CID and ETD...
journal article 2015
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Sorokin, D.Y. (author), Chernyh, N.A. (author), Poroshina, M.N. (author)
Recent intensive microbiological investigation of sulfidogenesis in soda lakes did not result in isolation of any pure cultures of sulfate-reducing bacteria (SRB) able to directly oxidize acetate. The sulfate-dependent acetate oxidation at haloalkaline conditions has, so far, been only shown in two syntrophic associations of novel...
journal article 2015
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Daran, J.G. (author), Geertman, J.M. (author), Bolat, I. (author)
The invention relates to a set of targeting constructs, comprising a first construct comprising a recognition site for an endonuclease, a first region of homology with a target gene of a microorganism, and a first part of a selection marker, and a second construct comprising a second part of the selection marker, a second region of homology with...
patent 2015
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Pronk, M. (author), Abbas, B. (author), Kleerebezem, R. (author), Van Loosdrecht, M.C.M. (author)
The influence of sludge age on granular sludge formation and microbial population dynamics in a methanol- and acetate-fed aerobic granular sludge system operated at 35°C was investigated. During anaerobic feeding of the reactor, methanol was initially converted to methane by methylotrophic methanogens. These methanogens were able to withstand...
journal article 2015
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Van Loosdrecht, M.C.M. (author), Lin, Y. (author), Pronk, M. (author)
The present invention concerns a method of producing linear polysaccharides, bacteria capable of producing such linear polysaccharides, and uses of such linear polysaccharides, as a medicament, in agriculture, in food processing, as a coating, as a thickening agent, as a flocculating agent, and for water processing.
patent 2015
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Milne, N. (author), Luttik, M.A.H. (author), Cueto Rojas, H.F. (author), Wahl, A. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.G. (author)
In microbial processes for production of proteins, biomass and nitrogen-containing commodity chemicals, ATP requirements for nitrogen assimilation affect product yields on the energy producing substrate. In Saccharomyces cerevisiae, a current host for heterologous protein production and potential platform for production of nitrogen-containing...
journal article 2015
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Janulevicius, A. (author), Van Loosdrecht, M.C.M. (author), Picioreanu, C. (author)
Myxobacteria are social bacteria that upon starvation form multicellular fruiting bodies whose shape in different species can range from simple mounds to elaborate tree-like structures. The formation of fruiting bodies is a result of collective cell movement on a solid surface. In the course of development, groups of flexible rod-shaped cells...
journal article 2015
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Van Loosdrecht, M.C.M. (author), Yuemei, L. (author), Lotti, T. (author)
The present invention is in the field of papermaking and relates in particular to sizing paper. Problems with state of the art methods are that the sizing chemicals used are typically expensive; may be available only in limited supply; are produced using methods that are damaging to the environment; and whose production is far from carbon...
patent 2015
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Fuzita, F.J. (author), Pinkse, M.W.H. (author), Patane, J.S.L. (author), Juliano, M.A. (author), Verhaert, P.D.E.M. (author), Lopes, A.R. (author)
Scorpions are among the oldest terrestrial arthropods and they have passed through small morphological changes during their evolutionary history on land. They are efficient predators capable of capturing and consuming large preys and due to envenomation these animals can become a human health challenge. Understanding the physiology of scorpions...
journal article 2015
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Muniz-Marquez, D.B. (author), Contreras, J.C. (author), Rodriguez, R. (author), Mussatto, S.I. (author), Wong-Paz, J.E. (author), Teixeira, J.A. (author), Aguilar, C.N. (author)
Agave syrup is a fermentable by-product from the Agave industry that is used for pulque production, a typical Mexican fermented beverage. However, to date, the information available on its physicochemical composition is scarce, with this study being one of the first contributions on the subject. Here the influence of thermal treatment at 121ºC...
journal article 2015
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Mooij, P.R. (author), Van Loosdrecht, M.C.M. (author), Kleerebezem, R. (author)
The invention is directed to a method for producing an enriched diatom culture, comprising subjecting a starting culture comprising one or more diatom species to selective pressure, thus giving a competitive advantage to storage compound producing species of diatoms, by subjecting said starting culture, under non-limiting bioavailable silicon...
patent 2015
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Sevcenco, A.M. (author), Paravidino, M. (author), Vrouwenvelder, J.S. (author), Wolterbeek, H.T. (author), Van Loosdrecht, M.C.M. (author), Hagen, W.R. (author)
Oxo-anion binding properties of the thermostable enzyme ferritin from Pyrococcus furiosus were characterized with radiography. Radioisotopes 32P and 76As present as oxoanions were used to measure the extent and the rate of their absorption by the ferritin. Thermostable ferritin proved to be an excellent system for rapid phosphate and arsenate...
journal article 2015
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Tamis, J. (author), Sorokin, D.Y. (author), Jiang, Y. (author), Van Loosdrecht, M.C.M. (author), Kleerebezem, R. (author)
Background Many waste streams have a relatively high vegetable oil content, which is a potential resource that should be recovered. Microbial storage compound production for the recovery of lipids from lipid-water emulsions with open (unsterilized) microbial cultures was investigated in a sequencing batch reactor using a diluted vegetable oil...
journal article 2015
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Mans, R. (author), Van Rossum, H.M. (author), Wijsman, M. (author), Backx, A. (author), Kuijpers, N.G.A. (author), van den Broek, M. (author), Daran-Lapujade, P.A.S. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author), Daran, J.G. (author)
A variety of techniques for strain engineering in Saccharomyces cerevisiae have recently been developed. However, especially when multiple genetic manipulations are required, strain construction is still a time-consuming process. This study describes new CRISPR/Cas9-based approaches for easy, fast strain construction in yeast and explores their...
journal article 2015
Searched for: department%3A%22BT%255C%257Eslsh%257EBiotechnology%22
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