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Ziliani, Agustina (author), Bovio-Winkler, Patricia (author), Cabezas, Angela (author), Etchebehere, Claudia (author), Garcia, Hector A. (author), López-Vázquez, Carlos M. (author), Brdjanovic, Damir (author), van Loosdrecht, Mark C.M. (author), Rubio-Rincón, Francisco J. (author)Ca. Accumulibacter was the predominant microorganism (relative FISH bio-abundance of 67 ± 5%) in a lab-scale sequential batch reactor that accomplished enhanced biological phosphorus removal (EBPR) while using glucose and acetate as the carbon sources (1:1 COD-based ratio). Both organic compounds were completely anaerobically consumed. The...journal article 2023
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Cerruti, M. (author), Crosset-Perrotin, G. (author), Ananth, Mythili (author), Rombouts, Julius Laurens (author), Weissbrodt, D.G. (author)Fermentative chemoorganoheterotrophic bacteria (FCB) and purple photoorganoheterotrophic bacteria (PPB) are two interesting microbial guilds to process carbohydrate-rich wastewaters. Their metabolic interactions have been studied in pure cultures or co-cultures, but little is known about mixed cultures. We studied the effect of reactor...journal article 2023
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Wei, P. (author), Haringa, C. (author), Portela, L. (author), Noorman, H.J. (author)This study focuses on the metabolic impacts of simultaneous glucose and oxygen concentration gradients on penicillin production in an industrial-scale fermentor, using the computational fluid dynamics-cellular reaction dynamics approach. Inclusion of oxygen-coupling considerably impacts the glucose uptake and resulting penicillin productivity...journal article 2023
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Quinzacara Sánchez, Ignacio (author)Addressing climate change is a challenge that governments, society, and companies have to face. For companies this becomes a major challenge as they are required to innovate in order to become more sustainable whilst still remain competitive. However, carrying out technological innovation may be useless if it cannot be diffused in the market....master thesis 2022
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Korkontzelos, Harry (author)The increasing demands for chemicals and fuels combined with the fuel versus food competition over first generation feedstocks requires the development of more sustainable alternatives. Syngas fermentation offers a sustainable production of fuels and recycling of gaseous and solid waste utilizing gas<br/>fermenting bacteria. Acetogens, such as...master thesis 2022
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Malubhoy, Zahabiya (author), Bahia, Frederico Mendonça (author), de Valk, Sophie Claire (author), de Hulster, A.F. (author), Rendulić, Toni (author), Ortiz, Juan Paulo Ragas (author), Xiberras, Joeline (author), Klein, Mathias (author), Mans, R. (author), Nevoigt, Elke (author)Background: The microbial production of succinic acid (SA) from renewable carbon sources via the reverse TCA (rTCA) pathway is a process potentially accompanied by net-fixation of carbon dioxide (CO<sub>2</sub>). Among reduced carbon sources, glycerol is particularly attractive since it allows a nearly twofold higher CO<sub>2</sub>-fixation...journal article 2022
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Puiman, L. (author), Abrahamson, Britt (author), van der Lans, R.G.J.M. (author), Haringa, C. (author), Noorman, H.J. (author), Picioreanu, C. (author)Mass transfer limitations in syngas fermentation processes are mostly attributed to poor solubility of CO and H<sub>2</sub> in water. Despite these assumed limitations, a syngas fermentation process has recently been commercialized. Using large-sale external-loop gas-lift reactors (EL-GLR), CO-rich off-gases are converted into ethanol, with...journal article 2022
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van Aalst, A.C.A. (author), Mans, R. (author), Pronk, J.T. (author)Background: Saccharomyces cerevisiae is intensively used for industrial ethanol production. Its native fermentation pathway enables a maximum product yield of 2 mol of ethanol per mole of glucose. Based on conservation laws, supply of additional electrons could support even higher ethanol yields. However, this option is disallowed by the...journal article 2022
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Almeida Benalcazar, E.F. (author), Noorman, H.J. (author), Maciel Filho, Rubens (author), Posada Duque, J.A. (author)This study explores key success factors for ethanol production via fermentation of gas streams, by assessing the effects of eight process variables driving the fermentation performance on the production costs and greenhouse gas emissions. Three fermentation feedstocks are assessed: off-gases from the steel industry, lignocellulosic biomass...journal article 2022
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Haringa, C. (author)Euler-Lagrange CFD simulations, where the biotic phase is represented by computational particles (parcels), provide information on environmental gradients inside bioreactors from the microbial perspective. Such information is highly relevant for reactor scale-down and process optimization. One of the major challenges is the computational...journal article 2022
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Haringa, C. (author), Tang, W. (author), Noorman, H.J. (author)The compartment model (CM) is a well-known approach for computationally affordable, spatially resolved hydrodynamic modeling of unit operations. Recent implementations use flow profiles based on Computational Fluid Dynamics (CFD) simulations, and several authors included microbial kinetics to simulate gradients in bioreactors. However, these...journal article 2022
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Puiman, Lars (author), Perdigão Elisiário, M. (author), Crasborn, Lilo M.L. (author), Wagenaar, Liselot E.C.H. (author), Straathof, Adrie J.J. (author), Haringa, C. (author)In gas fermentations (using O2, CO, H2, CH4 or CO2), gas-to-liquid mass transfer is often regarded as one of the limiting processes. However, it is widely known that components in fermentation broths (e.g., salts, biomass, proteins, antifoam, and organic products such as alcohols and acids) have tremendous impact on the volumetric mass transfer...journal article 2022
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Ceron Chafla, P.S. (author), García-Timermans, Cristina (author), de Vrieze, Jo (author), Ganigué, Ramon (author), Boon, Nico (author), Rabaey, Korneel (author), van Lier, J.B. (author), Lindeboom, R.E.F. (author)Fermentation at elevated hydrostatic pressure is a novel strategy targeting product selectivity. However, the role of inoculum history and cross-resistance, that is, acquired tolerance from incubation under distinctive environmental stress, remains unclear in high-pressure operation. In our here presented work, we studied fermentation and...journal article 2022
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Almeida Benalcazar, E.F. (author), Noorman, H.J. (author), Filho, Rubens Maciel (author), Posada Duque, J.A. (author)This study describes a methodological framework designed for the systematic processing of experimental syngas fermentation data for its use by metabolic models at pseudo-steady state and at transient state. The developed approach allows the use of not only own experimental data but also from experiments reported in literature which employ a...book chapter 2022
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Rabah, Malek (author)Upcycling of the biomass residues and wastes is a necessary innovation within the given environmental and economic trends, policies and regulations, competition and depletion of natural resources taking place nowadays. Thus, wood pallet upcycling is chosen in this thesis to be the ambassador of biomass. <br/>Research is built upon the...master thesis 2021
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Perdigão Elisiário, M. (author), De Wever, Heleen (author), Van Hecke, Wouter (author), Noorman, H.J. (author), Straathof, Adrie J.J. (author)Syngas fermentation to biofuels and chemicals is an emerging technology in the biobased economy. Mass transfer is usually limiting the syngas fermentation rate, due to the low aqueous solubilities of the gaseous substrates. Membrane bioreactors, as efficient gas–liquid contactors, are a promising configuration for overcoming this gas-to...review 2021
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Fang, Wei (author), Zhang, Xuedong (author), Spanjers, H. (author), Zhang, Tao (author)Persulfates ((peroxymonosulfate (PMS) and peroxydisulfate (PDS)) can disintegrate waste activated sludge (WAS), but their influence on volatile fatty acid (VFA) production during anaerobic fermentation is largely unclear. Particularly, it is unknown whether persulfates can improve fermentation without any preactivation. This study...journal article 2021
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Magalhaes de Medeiros, E. (author), Noorman, H.J. (author), Filho, Rubens Maciel (author), Posada Duque, J.A. (author)This work presents a strategy for optimizing the production process of ethanol via integrated gasification and syngas fermentation, a conversion platform of growing interest for its contribution to carbon recycling. The objective functions (minimum ethanol selling price (MESP), energy efficiency, and carbon footprint) were evaluated for the...journal article 2021
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Fernando Foncillas, C. (author), Cabrera Rodriguez, C.I. (author), Caparrós-Salvador, Francisco (author), Varrone, Cristiano (author), Straathof, Adrie J.J. (author)The aim of this work was to recover a mixture of carboxylates ranging from 2 to 7 carbon atoms using a strong anion exchange resin, followed by desorption with CO<sub>2</sub>-expanded methanol. Medium chain carboxylates hexanoate and heptanoate adsorbed better than acetate, and the corresponding medium chain carboxylic acids desorbed easier...journal article 2021
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Allaart, M.T. (author), Stouten, G.R. (author), Sousa, Diana Z. (author), Kleerebezem, R. (author)Anaerobic microbial communities can produce carboxylic acids of medium chain length (e.g., caproate, caprylate) by elongating short chain fatty acids through reversed β-oxidation. Ethanol is a common electron donor for this process. The influence of environmental conditions on the stoichiometry and kinetics of ethanol-based chain elongation...journal article 2021