Treatment Prediction in PDAC Patients: A Predictive Model for FOLFIRINOX Chemotherapy Response using Random Forest and Integrative Analysis of Blood and Tumor Markers

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a high mortality rate, poor prognosis, and a mere 7.7% 5-year survival rate [1] compared to 65% for all cancer types [2]. Approximately 80% of patients are diagnosed at the advanced stage [3], for which only palliative chemo(radio)therapy remains as treatment option. However,...

Reducing the non-value added movements in the interior logistics process: Study provided by yachtbuilder Oceanco

The supply for luxury yachts is growing which increases the competition between yachtbuilders. Additionally to lead time reduction, yachtbuilders are trying to maximise their output with the available space. This puts extra pressure on the logistics process. Waste in the logistics process reduces the efficiency and for that must be avoided. The...

Prediction of project performance; Development of a conceptual model for predicting future performance of an OG&C project in an EPC environment

The projects in oil and chemical (O&C) industry often experience problems during their execution, because of those problems, some of the project ends with large cost and schedule overruns. The poor performance of projects not only affects the strategic objective of project’s owner but also poses a dual threat to engineering and construction (E&C...

Development of a prediction model for speed limit violations on tangent road sections

Speeding and red light running are among the major causes for road crashes. Respectively, speeding is more crucial for rural areas, whereas red light running is more frequent in urban areas where most of the traffic lights are located. To adequately address both issues consistent actions are needed in three main directions (also known as the...