Searched for: subject:"STEM"
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Wittig, Corey (author)
Pulmonary arterial hypertension (PAH) is a complex, progressive disease characterized by an increased mean pulmonary arterial pressure at rest, and is associated with a high rate of mortality due to right ventricular failure as the disease progresses. While numerous animal and cell culture models have been created in an attempt to better...
master thesis 2019
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Vossen, T.E. (author), Henze, Ineke (author), Rippe, R. C.A. (author), van Driel, J.H. (author), de Vries, M.J. (author)
Research and design activities are important focus points in international policies for secondary Science, Technology, Engineering and Mathematics (STEM) education. It is up to school teachers to implement and supervise these activities in the STEM classroom. However, not much is known about the attitudes teachers hold towards supervising...
journal article 2019
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Vossen, T.E. (author), Tigelaar, E. H. (author), Henze, Ineke (author), de Vries, M.J. (author), van Driel, J.A.S. (author)
Technological design is a core activity in Science, Technology, Engineering and Mathematics (STEM) education. During the design process, students often employ research activities to enhance the quality of their design decisions and to rise above a mere trial-and-error approach to designing. There are many functions of research within the...
journal article 2019
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Croes, M. (author), Kruyt, Moyo C. (author), Boot, W. (author), Pouran, B. (author), Braham, M. V. (author), Pakpahan, S.A. (author), Weinans, H.H. (author), Vogely, H.C. (author), Fluit, Ad C. (author), Dhert, W.J.A. (author), Alblas, J (author), Oner, Fetullah C. (author)
Immune cells and their soluble factors regulate skeletal cells during normal bone regeneration and pathological bone formation. Bacterial infections can trigger immune responses that activate pro-osteogenic pathways, but these are usually overshadowed by osteolysis and concerns of systemic inflammation. The aim of this study was to determine...
journal article 2019
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Rahimi, E. (author), Kosari, A. (author), Hosseinpour, S. (author), Davoodi, Ali (author), Zandbergen, H.W. (author), Mol, J.M.C. (author)
In this study, we report on a combined microscopic, analytical and electrochemical characterization of the nanoscopic passive layer on a tungsten‑molybdenum-containing super duplex stainless steel. We used scanning transmission electron microscopy/energy dispersive X-ray spectroscopy, scanning Kelvin probe force microscopy, scanning tunneling...
journal article 2019
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Admiraal, Wilfried (author), Post, Lysanne (author), Guo, Pengyue (author), Saab, Nadira (author), Makinen, Sari (author), Rainio, Ohto (author), Vuori, Johanna (author), Kortuem, G.W. (author), Bourgeois, J. (author), Danford, Gerard (author)
One promising way to cope with changing requirements from the labor market in the domain of Science, Technology, Engineering and Mathematics (STEM), but also to keep the field up to date, to start innovations and to advance the STEM domain as such is the use of student labs. In these labs, students work together in small groups imitating...
journal article 2019
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Vossen, T.E. (author), Henze, Ineke (author), de Vries, M.J. (author), van Driel, J.A.S. (author)
Research and design activities are becoming more important in Science, Technology, Engineering and Mathematics (STEM) and D&T (design and technology) education. Research and design are often taught separately from each other, while in professional STEM practices, many projects are neither ‘research only’ or ‘design only’—they are both. In...
journal article 2019
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Guo, Y. (author), Aveyard, R.A. (author), Rieger, B. (author)
In this paper, we present a multichannel cross-modal fusion algorithm to combine two complementary modalities in electron tomography: X-ray spectroscopy and scanning transmission electron microscopy (STEM). The former reveals compositions with high elemental specificity but low signal-to-noise ratio (SNR), while the latter characterizes the...
journal article 2019
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Sharma, Abhishek (author)
A major challenge facing the study of bone regeneration today is the inability to mimic the tissue microenvironment and the factors comprising it. Organ-on-chip based microfluidic systems today aim at doing so by dynamically culturing living cells in them. These are preferred owing to their small feature sizes, laminar flows, high throughput,...
master thesis 2018
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Gelderman, Francisca (author)
In the current day and age, osteogenic bone implants are important to reduce healing time and infections after bone implantation. To help induce bone formation, the implant surface can be biofunctionalized with different agents. A promising surface modification technique used to treat titanium implants is Plasma Electrolytic Oxidation (PEO). In...
master thesis 2018
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Honig, Floris (author)
The use of material properties to guide cell behaviour is often utilised in the field of regenerative medicine. Regarding this, surface topography has been shown to control different cellular processes. In nature, topographies exist in a wide variety of shapes, including hierarchical structures with a great degree of surface roughness. Here,...
master thesis 2018
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Heerema, S.J. (author)
The information that can be extracted from DNA base sequences, is important for our understanding of biology, for insights in disease, and the way we practice medicine. The technology that one uses to determine DNA-base sequences is called ‘DNA sequencing’. A portable device that enables fast and accurate sequencing, can potentially greatly...
doctoral thesis 2018
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Vuik, V. (author), Suh Heo, H.Y. (author), Zhu, Zhenchang (author), Borsje, Bas W. (author), Jonkman, S.N. (author)
One of the services provided by coastal ecosystems is wave attenuation by vegetation, and subsequent reduction of wave loads on flood defense structures. Therefore, stability of vegetation under wave forcing is an important factor to consider. This paper presents a model which determines the wave load that plant stems can withstand before...
journal article 2018
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Heerema, S.J. (author), Vicarelli, L. (author), Pud, S. (author), Schouten, R.N. (author), Zandbergen, H.W. (author), Dekker, C. (author)
Many theoretical studies predict that DNA sequencing should be feasible by monitoring the transverse current through a graphene nanoribbon while a DNA molecule translocates through a nanopore in that ribbon. Such a readout would benefit from the special transport properties of graphene, provide ultimate spatial resolution because of the single...
journal article 2018
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Vossen, T.E. (author), Henze, Ineke (author), Rippe, R. C.A. (author), van Driel, J.H. (author), de Vries, M.J. (author)
Research and design activities are often employed in STEM (Science, Technology, Engineering & Mathematics) education. This study aims to examine students’ attitudes towards doing research and design activities in secondary school, among two groups of students: (1) students that take the quite recently introduced Dutch subject O&O ...
journal article 2018
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Nachenius, Auke (author)
This thesis contains the concept of a hand held device that is able to measure and classify the stem of avenue trees in a more automated matter with the ability to process the results digital. The measure concept is based on the technique of triangulating a 2D profile by using a slit laser and camera.
master thesis 2017
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El-Habr, Elias A. (author), Dubois, Luiz G. (author), Burel-Vandenbos, Fanny (author), Bogeas, Alexandra (author), Lipecka, Joanna (author), Turchi, Laurent (author), Lejeune, François Xavier (author), Coehlo, Paulo Lucas Cerqueira (author), Yamaki, Tomohiro (author), Wittmann, Bryan M. (author), Fareh, M. (author), Mahfoudhi, Emna (author), Janin, Maxime (author), Narayanan, Ashwin (author), Morvan-Dubois, Ghislaine (author), Schmitt, Charlotte (author), Verreault, Maité (author), Oliver, Lisa (author), Sharif, Ariane (author), Pallud, Johan (author), Devaux, Bertrand (author), Puget, Stéphanie (author), Korkolopoulou, Penelope (author), Varlet, Pascale (author), Ottolenghi, Chris (author), Plo, Isabelle (author), Moura-Neto, Vivaldo (author), Virolle, Thierry (author), Chneiweiss, Hervé (author), Junier, Marie Pierre (author)
Cell populations with differing proliferative, stem-like and tumorigenic states co-exist in most tumors and especially malignant gliomas. Whether metabolic variations can drive this heterogeneity by controlling dynamic changes in cell states is unknown. Metabolite profiling of human adult glioblastoma stem-like cells upon loss of their...
journal article 2017
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Kokorian, J. (author), van Spengen, W.M. (author)
In this paper we demonstrate a new method for analyzing and visualizing friction force measurements of meso-scale stick–slip motion, and introduce a method for extracting two separate dissipative energy components. Using a microelectromechanical system tribometer, we execute 2 million reciprocating sliding cycles, during which we measure the...
journal article 2017
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Aveyard, R.A. (author), Zhong, Z. (author), Batenburg, KJ (author), Rieger, B. (author)
Tomographic reconstruction algorithms offer a means by which a tilt-series of transmission images can be combined to yield a three dimensional model of the specimen. Conventional reconstruction algorithms assume that the measured signal is a linear projection of some property, typically the density, of the material. Here we report the use of...
journal article 2017
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Suh Heo, H.Y. (author)
Various flood protection measures are studied across the globe, and nature-friendly and environmentally resilient methods are gaining more attention. As part of the building with nature initiative, the project BE SAFE (Bio-Engineering for SAFEty) studies the effects of a vegetated foreshore as a flood protection measure which is found to be very...
master thesis 2016
Searched for: subject:"STEM"
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