document

Laser-driven resonance of dye-doped oil-coated microbubbles: Experimental study

Lajoinie, Guillaume (author), Lee, Jeong Yu (author), Owen, Joshua (author), Kruizinga, P. (author), de Jong, N. (author), Van Soest, Gijs (author), Stride, Eleanor (author), Versluis, Michel (author)

Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an...

journal article 2017

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A Front-End ASIC with Receive Sub-array Beamforming Integrated with a 32 × 32 PZT Matrix Transducer for 3-D Transesophageal Echocardiography

Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Ponte, Jacco (author), Prins, Christian (author), Vos, H.J. (author), Bosch, J.G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography. The 6.1 × 6.1 mm² ASIC, implemented...

journal article 2017

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A Front-End ASIC With High-Voltage Transmit Switching and Receive Digitization for 3-D Forward-Looking Intravascular Ultrasound Imaging

Tan, M. (author), Chen, C. (author), Chen, Z. (author), Janjic, Jovana (author), Daeichin, V. (author), Chang, Z.Y. (author), Noothout, E.C. (author), van Soest, G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, and has a circular active area with a diameter of 1.5 mm on the top of which a 2-D array of piezoelectric transducer elements is...

journal article 2018

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A Reconfigurable Ultrasound Transceiver ASIC With 24 x 40 Elements for 3-D Carotid Artery Imaging

Kang, E. (author), Ding, Q. (author), Shabanimotlagh, M. (author), Kruizinga, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J.W. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm² ASIC...

journal article 2018

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Fast Volumetric Imaging Using a Matrix Transesophageal Echocardiography Probe with Partitioned Transmit–Receive Array

Bera, D. (author), Van Den Adel, Franc (author), Radeljic-Jakic, Nikola (author), Lippe, Boris (author), Soozande, M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Kruizinga, P. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), Bosch, Johan G. (author), de Jong, N. (author)

We describe a 3-D multiline parallel beamforming scheme for real-time volumetric ultrasound imaging using a prototype matrix transesophageal echocardiography probe with diagonally diced elements and separated transmit and receive arrays. The elements in the smaller rectangular transmit array are directly wired to the ultrasound system. The...

journal article 2018

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Acoustic characterization of a miniature matrix transducer for pediatric 3D transesophageal echocardiography

Daeichin, V. (author), Bera, D. (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Chen, Z. (author), Chen, C. (author), Noothout, E.C. (author), Vos, H.J. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author)

This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32 × 32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a...

journal article 2018

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A 2D Ultrasound Transducer with Front-End ASIC and Low Cable Count for 3D Forward-Looking Intravascular Imaging: Performance and Characterization

Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)

Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...

journal article 2018

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Multiline 3D beamforming using micro-beamformed datasets for pediatric transesophageal echocardiography

Bera, D. (author), Raghunathan, S.B. (author), Chen, C. (author), Chen, Z. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bosch, J.G. (author)

Until now, no matrix transducer has been realized for 3D transesophageal echocardiography (TEE) in pediatric patients. In 3D TEE with a matrix transducer, the biggest challenges are to connect a large number of elements to a standard ultrasound system, and to achieve a high volume rate (>200 Hz). To address these issues, we have recently...

journal article 2018

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Measurement of Pipe and Fluid Properties with a Matrix Array-based Ultrasonic Clamp-on Flow Meter

Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Sabbadini, A. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)

Current ultrasonic clamp-on flow meters consist of a pair of single-element transducers that are carefully positioned before use. This positioning process consists of manually finding the distance between the transducer elements, along the pipe axis, for which maximum signal-to-noise ratio (SNR) is achieved. This distance depends on the sound...

journal article 2021

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Combining ultrafast ultrasound and high-density EMG to assess local electromechanical muscle dynamics: a feasibility study

Waasdorp, R. (author), Mugge, W. (author), Vos, H.J. (author), De Groot, Jurriaan H. (author), Verweij, M.D. (author), de Jong, N. (author), Schouten, A.C. (author), Daeichin, V. (author)

Skeletal muscles generate force, enabling movement through a series of fast electro-mechanical activations coordinated by the central nervous system. Understanding the underlying mechanism of such fast muscle dynamics is essential in neuromuscular diagnostics, rehabilitation medicine and sports biomechanics. The unique combination of...

journal article 2021

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Design of an ultrasound transceiver asic with a switching-artifact reduction technique for 3D carotid artery imaging

Kim, Taehoon (author), Fool, F. (author), Simoes dos Santos, D. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) directly integrated with an array of 12 × 80 piezoelectric transducer elements to enable next-generation ultrasound probes for 3D carotid artery imaging. The ASIC, implemented in a 0.18 µm high-voltage Bipolar-CMOS-DMOS (HV BCD) process, adopted a...

journal article 2021

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Finite Transducer Size Compensation in Two-Dimensional Photoacoustic Computed Tomography

Hakakzadeh, Soheil (author), Mozaffarzadeh, M. (author), Mostafavi, Seyed Masood (author), Amjadian, Mohammadreza (author), Kavehvash, Zahra (author), Verweij, M.D. (author), de Jong, N. (author)

In circular photoacoustic computed tomography, for data acquisition, a single-element transducer rotates around the region of interest (ROI). Due to the limited acceptance angle of the finite size transducer, the reconstructed image becomes blurred, and tangential resolution/contrast degrades in off-center locations in the ROI. In this paper, we...

conference paper 2021

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Experimental Investigation of the Effect of Subdicing on an Ultrasound Matrix Transducer

Simoes dos Santos, D. (author), Fool, F. (author), Kim, Taehoon (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), de Jong, N. (author)

Over the past decades, real-time three-dimensional (3D) medical ultrasound has attracted much attention since it enables clinicians to diagnose more accurately. This calls for ultrasound matrix transducers with a large number of elements, which can be interfaced with an application-specific integrated circuit (ASIC) for data reduction. An...

conference paper 2021

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Measurement of Pipe and Liquid Parameters Using the Beam Steering Capabilities of Array-Based Clamp-On Ultrasonic Flow Meters

Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author)

Clamp-on ultrasonic flow meters (UFMs) are installed on the outside of the pipe wall. Typically, they consist of two single-element transducers mounted on angled wedges, which are acoustically coupled to the pipe wall. Before flow metering, the transducers are placed at the correct axial position by manually moving one transducer along the pipe...

journal article 2022

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Multi-angle data acquisition to compensate transducer finite size in photoacoustic tomography

Hakakzadeh, Soheil (author), Mozaffarzadeh, M. (author), Mostafavi, S.. (author), Kavehvash, Zahra (author), Rajendran, Praveenbalaji (author), Verweij, M.D. (author), de Jong, N. (author), Pramanik, Manojit (author)

In photoacoustic tomography (PAT) systems, the tangential resolution decreases due to the finite size of the transducer as the off-center distance increases. To address this problem, we propose a multi-angle detection approach in which the transducer used for data acquisition rotates around its center (with specific angles) as well as around...

journal article 2022

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A Pitch-Matched Transceiver ASIC With Shared Hybrid Beamforming ADC for High-Frame-Rate 3-D Intracardiac Echocardiography

Hopf, Y.M. (author), Ossenkoppele, Boudewine W. (author), Soozande, Mehdi (author), Noothout, E.C. (author), Chang, Z.Y. (author), Chen, Chao (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

In this article, an application-specific integrated circuit (ASIC) for 3-D, high-frame-rate ultrasound imaging probes is presented. The design is the first to combine element-level, high-voltage (HV) transmitters and analog front-ends, subarray beamforming, and in-probe digitization in a scalable fashion for catheter-based probes. The...

journal article 2022

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A Pitch-Matched Low-Noise Analog Front-End With Accurate Continuous Time-Gain Compensation for High-Density Ultrasound Transducer Arrays

Guo, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, Johan G. (author), de Jong, N. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author)

This article presents a compact analog front-end (AFE) circuit for ultrasound receivers with linear-in-dB continuous gain control for time-gain compensation (TGC). The AFE consists of two variable-gain stages, both of which employ a novel complementary current-steering network (CCSN) as the interpolator to realize continuously variable gain....

journal article 2022

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A Compact Integrated High-Voltage Pulser Insensitive to Supply Transients for 3-D Miniature Ultrasound Probes

Hopf, Y.M. (author), Ossenkoppele, B.W. (author), Soozande, M. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)

In this letter, a compact high-voltage (HV) transmit circuit for dense 2-D transducer arrays used in 3-D ultrasonic imaging systems is presented. Stringent area requirements are addressed by a unipolar pulser with embedded transmit/receive switch. Combined with a capacitive HV level shifter, it forms the ultrasonic HV...

journal article 2022

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Sparse 2-D PZT-on-PCB Arrays With Density Tapering

Wei, Luxi (author), Boni, Enrico (author), Ramalli, Alessandro (author), Fool, F. (author), Noothout, E.C. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Tortoli, Piero (author), de Jong, N. (author), Vos, H.J. (author)

Two-dimensional (2-D) arrays offer volumetric imaging capabilities without the need for probe translation or rotation. A sparse array with elements seeded in a tapering spiral pattern enables one-to-one connection to an ultrasound machine, thus allowing flexible transmission and reception strategies. To test the concept of sparse spiral array...

journal article 2022

document

Design and Proof-of-Concept of a Matrix Transducer Array for Clamp-on Ultrasonic Flow Measurements

Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Noothout, E.C. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)

Common clamp-on ultrasonic flow meters consist of two single-element transducers placed on the pipe wall. Flow speed is measured noninvasively, i.e., without interrupting the flow and without perforating the pipe wall, which also minimizes safety risks and avoids pressure drops inside the pipe. However, before metering, the transducers have...

journal article 2022