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de Kater, E.P. (author), Müller, R. (author), Sakes, A. (author), Breedveld, P. (author)The fixation strength of pedicle screws could be increased by fixating along the much stronger cortical bone layer, which is not possible with the current rigid and straight bone drills. Inspired by the tsetse fly, a single-plane steerable bone drill was developed. The drill has a flexible transmission using two stacked leaf springs such that...journal article 2023
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King, Andrew J. (author), Portugal, Steven J. (author), Strömbom, Daniel (author), Mann, Richard P. (author), Carrillo, José A. (author), Kalise, Dante (author), de Croon, G.C.H.E. (author), Barnett, Heather (author), Scerri, Paul (author)A single sheepdog can bring together and manoeuvre hundreds of sheep from one location to another. Engineers and ecologists are fascinated by this sheepdog herding because of the potential it provides for ‘bio-herding’: a biologically inspired herding of animal groups by robots. Although many herding algorithms have been proposed, most are...journal article 2023
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Afschrift, M. (author), van Asseldonk, E. (author), van Mierlo, M. (author), Bayon, C. (author), Keemink, A. (author), D’Hondt, L. (author), van der Kooij, H. (author), De Groote, F. (author)Background: Balance control is important for mobility, yet exoskeleton research has mainly focused on improving metabolic energy efficiency. Here we present a biomimetic exoskeleton controller that supports walking balance and reduces muscle activity. Methods: Humans restore balance after a perturbation by adjusting activity of the muscles...journal article 2023
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Vercruyssen, Tim G.A. (author), Henrion, Sebastian (author), Müller, Ulrike K. (author), van Leeuwen, Johan L. (author), van der Helm, F.C.T. (author)Autonomous robots are used to inspect, repair and maintain underwater assets. These tasks require energy-efficient robots, including efficient movement to extend available operational time. To examine the suitability of a propulsion system based on undulating fins, we built two robots with one and two fins, respectively, and conducted a...journal article 2023
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Pagani, Stefania (author), Salerno, Manuela (author), Filardo, Giuseppe (author), Locs, Janis (author), van Osch, G.J.V.M. (author), Vecstaudza, Jana (author), Dolcini, Laura (author), Borsari, Veronica (author), Fini, Milena (author), Giavaresi, Gianluca (author), Columbaro, Marta (author)Osteochondral lesions, when not properly treated, may evolve into osteoarthritis (OA), especially in the elderly population, where altered joint function and quality are usual. To date, a collagen/collagen–magnesium–hydroxyapatite (Col/Col-Mg-HAp) scaffold (OC) has demonstrated good clinical results, although suboptimal subchondral bone...journal article 2023
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Pitta Kruize, Carlos (author), Panahkhahi, S. (author), Putra, N.E. (author), Diaz Payno, P.J. (author), van Osch, G.J.V.M. (author), Zadpoor, A.A. (author), Mirzaali, Mohammad J. (author)Bone-to-soft tissue interfaces are responsible for transferring loads between tissues with significantly dissimilar material properties. The examples of connective soft tissues are ligaments, tendons, and cartilages. Such natural tissue interfaces have unique microstructural properties and characteristics which avoid the abrupt transitions...review 2023
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Gosztonyi, S. (author)Adaptive façades are designed to actively regulate the exchange of material and energy flows and thus improve the balance between comfort and energy consumption. However, their technical complexity leads to higher development efforts, maintenance and costs, and ultimately fewer implementations. <br/>Embedded adaptive functions could be an...doctoral thesis 2022
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Fragasso, A. (author), de Vries, Hendrik W. (author), Andersson, John (author), van der Sluis, E.O. (author), van der Giessen, Erik (author), Onck, Patrick R. (author), Dekker, C. (author)Nuclear pore complexes (NPCs) regulate all molecular transport between the nucleus and the cytoplasm in eukaryotic cells. Intrinsically disordered Phe-Gly nucleoporins (FG-Nups) line the central conduit of NPCs to impart a selective barrier where large proteins are excluded unless bound to a transport receptor (karyopherin; Kap). Here, we...journal article 2022
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Lekkala, Malakonda Reddy (author), Latheef, Mohamed (author), Jung, Jae Hwan (author), Coraddu, A. (author), Zhu, Hongjun (author), Srinil, Narakorn (author), Lee, Byung Hyuk (author), Kim, Do Kyun (author)The application of unsteady incompressible flow phenomenon over the bluff bodies has received the attention of many researchers due to the rich and complex physics underpinning these flows, and thus requiring special attention in their modelling and numerical simulations. The wake that forms at the leeside of the bluff body is of particular...review 2022
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van den Berg, S.C. (author), Scharff, R.B.N. (author), Rusak, Z. (author), Wu, J. (author)We present OpenFish: an open source soft robotic fish which is optimized for speed and efficiency. The soft robotic fish uses a combination of an active and passive tail segment to accurately mimic the thunniform swimming mode. Through the implementation of a novel propulsion system that is capable of achieving higher oscillation frequencies...journal article 2022
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Tchekwagep, Patrick Marcel Seumo (author), Crapnell, Robert D. (author), Banks, Craig E. (author), Betlem, K. (author), Rinner, Uwe (author), Canfarotta, Francesco (author), Lowdon, Joseph W. (author), Eersels, Kasper (author), van Grinsven, Bart (author), Peeters, Marloes (author), McClements, Jake (author)Molecular recognition has been described as the “ultimate” form of sensing and plays a fundamental role in biological processes. There is a move towards biomimetic recognition elements to overcome inherent problems of natural receptors such as limited stability, high-cost, and variation in response. In recent years, several alternatives have...review 2022
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Cruz Saldivar, M. (author), Doubrovski, E.L. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Bio-inspired composites are a great promise for mimicking the extraordinary and highly efficient properties of natural materials. Recent developments in voxel-by-voxel 3D printing have enabled extreme levels of control over the material deposition, yielding complex micro-architected materials. However, design complexity, very large degrees of...journal article 2022
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Tschiersky, Martin (author), Hekman, Edsko E.G. (author), Herder, J.L. (author), Brouwer, Dannis M. (author)Passive shoulder supports show large potential for a wide range of applications, such as assisting activities of daily living and supporting work-related tasks. The rigid-link architecture used in currently available devices, however, may pose an obstacle to finding designs that offer low protrusion and close-to-body alignment. This study...journal article 2022
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Veeger, Robin (author)Functional gradients in hard-soft interfaces are abundant in nature, and we often mimic them to create strong and tough composites. A powerful tool for the designs and fabrication of biomimetic composites is voxel-based multi-material 3D printing. Earlier researches mainly focused on using this technique in the creation of gradients based on...master thesis 2021
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Fragasso, A. (author)At first glance nanopores may appear simple, almost intuitive, to understand given that they are, quite literally, ‘just’ very small pores in a membrane. In fact, one may even wonder why at all we need trained scientists to study such seemingly simple entities. The short answer is that nanopores, as the word suggests, are nanoscale entities and,...doctoral thesis 2021
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Pitta Kruize, Carlos (author)The mechanical properties of biological hard-soft interfaces change gradually over a small surface area to prevent the formation of stress concentrations through variations in the interface’s chemical composition, microstructure and geometry. The bone-tendon/ligament and bone-cartilage interface are the most prominent hard-soft interfaces within...master thesis 2021
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Copier, Rick (author)Objective: this paper aims to evaluate the adhesive and frictional properties of the keratinised epithelium on the adhesive pads of tree frogs. Modeling methods: two modeling methods have been developed. One of these methods involves the implementation of discrete fibres in a relatively compliant material matrix while the other method involves...master thesis 2021
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de Kater, E.P. (author), Sakes, A. (author), Bloemberg, J. (author), Jager, D.J. (author), Breedveld, P. (author)Tissue transport is a challenge during Minimally Invasive Surgery (MIS) with the current suction-based instruments as the increasing length and miniaturisation of the outer diameter requires a higher pressure. Inspired by the wasp ovipositor, a slender and bendable organ through which eggs can be transported, a flexible transport mechanism for...journal article 2021
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Manoonpong, Poramate (author), Patanè, Luca (author), Xiong, Xiaofeng (author), Brodoline, Ilya (author), Dupeyroux, J.J.G. (author), Viollet, Stéphane (author), Arena, Paolo (author), Serres, Julien R. (author)This review article aims to address common research questions in hexapod robotics. How can we build intelligent autonomous hexapod robots that can exploit their biomechanics, morphology, and computational systems, to achieve autonomy, adaptability, and energy efficiency comparable to small living creatures, such as insects? Are insects good...review 2021
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A Tailor-Made Deazaflavin-Mediated Recycling System for Artificial Nicotinamide Cofactor BiomimeticsDrenth, Jeroen (author), Yang, Guang (author), Paul, C.E. (author), Fraaije, Marco W. (author)Nicotinamide adenine dinucleotide (NAD) and its 2′-phosphorylated form NADP are crucial cofactors for a large array of biocatalytically important redox enzymes. Their high cost and relatively poor stability, however, make them less attractive electron mediators for industrial processes. Nicotinamide cofactor biomimetics (NCBs) are easily...journal article 2021