- document
-
van Heijst, S.E. (author)Two-dimensional (2D) layered materials have attracted the interest of the scientific community following the discovery of graphene and its extraordinary properties. Of particular interest is a class of materials called transition metal dichalcogenides (TMDs). The materials within this class were discovered to show similarly...doctoral thesis 2024
- document
-
Wang, W. (author)This thesis explores advanced computational techniques in super-resolution microscopy (SRM), with the primary goal of pushing the limits of achievable resolution towards the 1 nm scale. It includes developments in particle fusion algorithms, data analysis of complex biological structures, and exploration of the impact of molecular dipole...doctoral thesis 2024
- document
- Gobeil, J. (author) doctoral thesis 2023
- document
-
Zuidema, W. (author)In this thesis, the design and engineering considerations for a multi-beam scanning electron microscope (MBSEM) are discussed. This microscope can benefit biological research in various ways. It can give new insights into the inner workings of a multitude of biological systems that were hard to get using previously existing instrumentation. For...doctoral thesis 2023
- document
-
Arora, S. (author)The aimof this thesis is to investigate the impact of symmetry on light and how it alters its characteristics. Our research centers around the examination of complex photonic crystals rooted in the concept of photonic topological insulators, which are analogs of topological insulators initially introduced in condensed matter physics. Unlike...doctoral thesis 2023
- document
-
Maddalena, L. (author)Optogenetics is a powerful addition to the spectrum of techniques available in neuroscience to investigate neurophysiology and unravel how neural circuit structure is related to circuit function. This technique relies on introducing lightsensitive proteins or molecules as actuators to transduce an optical signal into a physiological perturbation...doctoral thesis 2022
- document
-
Lane, R. (author)Multi-modal imaging techniques have become essential for better understanding fundamental questions in cell biology such as disease progression. While individual microscopy methods have rapidly advanced in recent years, the information content of any one imaging technique is limited to the type of contrast that particular technique is sensitive...doctoral thesis 2022
- document
-
Chandrashekar, A. (author)Most physical phenomena be it mechanical, chemical or biological are inherently nonlinear in nature. In fact, it is the linear phenomenon that is the exception rather than the rule. By harnessing these nonlinearities one can obtain far greater information about the underlying physics and develop more sensitive and efficient devices. This is...doctoral thesis 2022
- document
-
Rejali, R. (author)This thesis focuses on possible platforms for a bottom-up approach towards realizing and characterizing atomically assembled magnetic and electronic artificial lattices. For this, we make use of the scanning tunneling microscope (STM), which provides a local probe of the magnetic and electronic properties of the sample and allows for the atom-by...doctoral thesis 2022
- document
-
Fu, Y. (author)When high-temperature steels are loaded under under industrially relevant conditions not only creep (i.e. a time dependent strain increase even under nominally constant loading conditions) occurs, but also local damage is formed. At relatively short exposure times quasi-spherical micron-sized cavities form preferentially at the grain boundaries...doctoral thesis 2022
- document
-
Marques Pereira, V. (author)An approach to improve the performance of steels for fusion and fission reactors is to reinforce them with oxide nanoparticles. These can hinder dislocation and grain boundary movement and trap radiation-induced defects, thus increasing creep and radiation damage resistance. Steels containing these oxide particles are called ODS steels (Oxide...doctoral thesis 2022
- document
-
Hulleman, C.N. (author)<i>Localization microscopy has circumvented the diffraction limit by sequentially</i> imaging individual light emitting molecules at a time. The position of these individual molecules can be determined and a super-resolution reconstruction is made with improved resolution. Normally freely rotating emitters are used such that the point spread...doctoral thesis 2021
- document
-
Maduro, L.A. (author)The family of transitionmetal dichalcogenides offer a unique platformfor electronic and optical tunability due to the sensitivity to their dimensional configuration, edge terminations, and varying crystal phases. In this thesis we focus on structures based on the transition metal dichalcogenides MoS2 and WS2. We study how different crystal...doctoral thesis 2021
- document
-
Bijster, R.J.F. (author)In this thesis a proof-of-principle demonstration is developed that uses the heat flux between a probe and a sample as a proxy for their separation. The proposed architecture uses a probe that consists of a bilayer cantilever with an attached sphere at its free end. The deflection of the cantilever that is caused by the heat input is measured...doctoral thesis 2021
- document
-
Dreesens, L.L. (author)Phages are nanomachines composed of a protein coat encapsulating a genome. Since they are metabolically inert, they depend on a bacterial host for replication. They are abundantly present in all kinds of environments, patiently awaiting their target. The nanoscopic mechanical details of how phages or phage-like particles find the correct target...doctoral thesis 2021
- document
-
Krielaart, M.A.R. (author)We propose a microscopy scheme for the controlled modulation of the electron wave front that utilizes patterned electron mirrors. The ability to control the wave front of the electron finds many applications in electron microscopy, for instance in contrast enhancement techniques, beam mode conversion, low-dose imaging techniques such as quantum...doctoral thesis 2021
- document
-
Janssen, V.A.E.C. (author)This thesis describes research into the interaction between electrons and various (pseudo) two-dimensional materials. This research is using two approaches: in Chapters 3 and 4 a low-energy electron microscope is used, and in Chapters 5 and 6 transport properties are studied. Chapter 1 introduces the concept of a two-dimensional material. First,...doctoral thesis 2020
- document
-
Büke, F. (author)Bacteria have been an integral part of human life since the ancient times either as cooperative tenants living in and around us or as constant threats to our health and wellbeing. Since prehistoric times we unknowingly used them as tools of fermentation and fought against them with haphazardly discovered natural remedies. Today, after more than...doctoral thesis 2020
- document
-
van Rooij, J. (author)Optical imaging is the imaging of objects with visible light. It is a tool often used for diagnostic purposes, such as in biomedical and material sciences. Digital holography is an optical imaging technique that captures and images the amplitude as well as the phase (the complex amplitude) of the lightwave. An advantage is that the complex...doctoral thesis 2020
- document
-
Deb Roy, S. (author)The basis of this thesis has been the curiosity, however modest, to understand how DNA replication happens in vivo, particularly during the onset of DNA damage and beyond. DNA damage is a recurring phenomenon, which a (bacterial) cell faces in its lifetime from the environment or even its inherent metabolism. While we understand much about...doctoral thesis 2020