Pages
- 1
- 2
- document
-
Sheykhzadeh, Morteza (author), Ghasemi, Rohollah (author), Vandchali, Hadi Rezaei (author), Sepehri, A. (author), Torabi, Seyed Ali (author)Due to the outbreak of COVID-19 around the globe in the last few years, the need for pharmaceutical supply chains is felt more than before. However, increasing uncertainties along with unpredictable demand for products led to disruptions in supply chains when receiving requests from retailers. These disruptions not only affected the economic...journal article 2024
- document
-
Moradi, N. (author), Lopez Vazquez, C.M. (author), Hernandez, Hector Garcia (author), Proskynitopoulou, Vera (author), Vouros, Anastasios (author), Garagounis, Ioannis (author), Lorentzou, Souzana (author), Brdjanovic, Damir (author), van Loosdrecht, Mark C.M. (author)In recent decades, there has been a growing focus on the management and valorization of digestate, primarily driven by its nutrient-rich composition, which positions it as a promising resource for biofertilizer production. However, several countries still restrict the direct application of digestate due to its potential environmental hazard,...journal article 2024
- document
-
Ahmadi, Navid (author), Abbasi, Mona (author), Torabian, Ali (author), van Loosdrecht, Mark C.M. (author), Ducoste, Joel (author)We investigated the transformation of four pharmaceuticals (Diclofenac, Naproxen, Ibuprofen and Carbamazepine) in a moving bed biofilm reactor subjected to different COD/N ratios in four experimental phases. The shift from medium to high range COD/N ratio (i.e., 5:1 to 100:1) intensified the competition between heterotrophs and nitrifying...journal article 2023
- document
-
Marin, Nicoleta Mirela (author), Stanculescu, I.R. (author)The purpose of the research consists of: i) development of a new specific adsorption method for two anesthetic drugs, procainamide (PHA) and lidocaine (LID) from aqueous solutions on Amberlite XAD7HP polyester resin and ii) obtaining a high-performance new material, PHA respectively LID loaded resin, for As(V), Cd(II) and Pb(II) metallic ions...journal article 2022
- document
-
Keetels, G.H. (author), Godderis, L. (author), van de Wiel, B.J.H. (author)Background: Both influenza and SARS-CoV-2 viruses show a strong seasonal spreading in temperate regions. Several studies indicated that changes in indoor humidity could be one of the key factors explaining this. Objective: The purpose of this study is to quantify the association between relevant epidemiological metrics and humidity in both...journal article 2022
- document
- Zhang, Yongjun (author), Hu, Jiangyong (author), Nomngongo, Philiswa Nosizo (author), Wang, Qilin (author), Spanjers, H. (author) contribution to periodical 2022
- document
-
Dedehayir, Ozgur (author), Mäkinen, Saku J. (author), Ortt, J.R. (author)Despite their importance little is known about how innovation ecosystems come into existence. We address this gap through an historical case study Herceptin, a revolutionary drug developed for the treatment of ovarian and breast cancer, and the innovation ecosystem that emerged around this drug between 1978 and 1998. Through qualitative content...journal article 2022
- document
-
La Zara, D. (author)The majority of pharmaceutical products is made of solid powders. The morphology and surface characteristics of drug particles affect both their bulk behaviour, e.g., flowability, dispersibility and tabletability, in the manufacturing process of dosage forms as well as their bioavailability upon administration into the human body. For instance,...doctoral thesis 2021
- document
-
Roschangar, Frank (author), Li, Jun (author), Zhou, Yanyan (author), Aelterman, Wim (author), Borovika, Alina (author), Colberg, Juan (author), Dickson, David P. (author), Gallou, Fabrice (author), Sheldon, R.A. (author)The large and steadily growing demand for medicines combined with their inherent resource-intensive manufacturing necessitates a relentless push for their sustainable production. Pharmaceutical companies are constantly seeking to perform reliable life cycle assessments of their medicinal products and assess the true value of their sustainable...journal article 2021
- document
-
Amoroso, Rosa (author), Hollmann, F. (author), Maccallini, Cristina (author)DES are mixtures of two or more compounds, able to form liquids upon mixing, with lower freezing points when compared to the individual constituents (eutectic mixtures). This attitude is due to the specific hydrogen-bond interactions network between the components of the mixture. A notable characteristic of DES is the possibility to develop...review 2021
- document
-
La Zara, D. (author), Zhang, F. (author), Sun, F. (author), Bailey, Maximilian R. (author), Quayle, Michael J. (author), Petersson, Gunilla (author), Folestad, Staffan (author), van Ommen, J.R. (author)The wettability of pharmaceuticals is a key physical property which influences their dissolution rate, dispersibility, flowability and solid-state stability. Here, we provide a platform of surface nanoengineering methods capable of tuning the wettability of drug powders from high hydrophilicity to superhydrophobicity with drug loadings up to...journal article 2021
- document
-
Romolo, Francesco Saverio (author), Sarilar, M. (author), Antoine, Johann (author), Mestria, Serena (author), Strano Rossi, Sabina (author), Gallidabino, Matteo Davide (author), Soares de Souza, Guilherme Maurício (author), Chytry, Paola (author), Ferraz Dias, Johnny (author)Illegal trafficking of pharmaceutical products by criminal organisations is a global threat for public health. Drugs for erectile dysfunction such as phosphodiesterase type 5 inhibitors are the most commonly counterfeited medicines in Europe. The search of possible toxic chemical substances in seized products is needed to provide early...journal article 2020
- document
-
Kooijman, G. (author), de Kreuk, M.K. (author), Houtman, C. (author), van Lier, J.B. (author)Literature frequently reports that colloids in aqueous matrices sorb a large fraction of pharmaceuticals. Since coagulation/flocculation removes colloids, it is expected that coagulation/flocculation in principle should be useful in concentrating pharmaceuticals in wastewater treatment, which would facilitate the treatment of these refractory...journal article 2020
- document
-
Zhang, Di (author), La Zara, D. (author), Quayle, Michael J. (author), Petersson, Gunilla (author), van Ommen, J.R. (author), Folestad, Staffan (author)The morphology, size, and surface properties of pharmaceutical particles form an essential role in the therapeutic performance of active pharmaceutical ingredients (APIs) and excipients as constituents in various drug delivery systems and clinical applications. Recent advances in methods for surface modification, however, rely heavily on...journal article 2019
- document
-
Pastrana-Martínez, Luisa M. (author), Morales-Torres, Sergio (author), Carabineiro, Sónia A.C. (author), Buijnsters, J.G. (author), Figueiredo, José L. (author), Silva, Adrián M.T. (author), Faria, Joaquim L. (author)Pristine nanodiamonds (NDs) obtained by detonation, or functionalized by different treatments, namely oxidation, hydrogenation and amination, were used to synthesize composites by insertion in TiO<sub>2</sub> matrixes. The different treatments of the NDs lead to materials containing diverse texture properties and surface chemistry...journal article 2018
- document
-
Sharma, H. (author), Sietsma, J. (author), Offerman, S.E. (author)Polymorphism is the ability of a solid material to exist in more than one phase or crystal structure. Polymorphism may occur in metals, alloys, ceramics, minerals, polymers, and pharmaceutical substances. Unresolved are the conditions for preferential nucleation during polymorphic transformations in which structural relationships or special...journal article 2016
- document
-
Uhlig, T. (author), Kyprianou, T.D. (author), Martinelli, F.G. (author), Oppici, C.A. (author), Heiligers, D. (author), Hills, D.R.J. (author), Calvo, X.R. (author), Verhaert, P.D.E.M. (author)This minireview touches upon the challenges and opportunities peptides experience on the track to become an approved pharmaceutical. Peptide attributes originally considered troublesome with respect to drug development may now turn out to be more convenient rather than unfavourable. Besides characteristic high target affinity, biological...journal article 2014
- document
-
Hut, R. (author), Van de Giesen, N. (author), Houtman, C.J. (author)The relation between pharmaceutical residues along the river Rhine and the demographic characteristics of the upstream population was studied. A sampling campaign was performed in which water samples from the Rhine were taken at 42 locations. Measurements were compared to a two parameter model with regional demographic data as main input. For 12...journal article 2013
- document
-
Lakerveld, R. (author), Benyahia, B. (author), Heider, P.L. (author), Zhang, H. (author), Braatz, R.D. (author), Barton, P.I. (author)The judicious use of buffering capacity is important in the development of future continuous pharmaceutical manufacturing processes. The potential benefits are investigated of using optimal-averaging level control for tanks that have buffering capacity for a section of a continuous pharmaceutical pilot plant involving two crystallizers, a...journal article 2013
- document
-
Maeng, S.K. (author)This study showed that BF is an effective multiple objective barrier for removal of different contaminants present in surface water sources including bulk organic matter and organic micropollutants (OMPs) like pharmaceutically active compounds and endocrine disrupting compounds. It was found that biodegradation and adsorption play primary and...doctoral thesis 2010
Pages
- 1
- 2