NL
Nathanael Lampe
Authored
20 records found
Towards photon radiotherapy treatment planning with high Z nanoparticle radiosensitisation agents
The Relative Biological Effective Dose (RBED) framework
A novel treatment planning framework, the Relative Biological Effective Dose (RBED), for high Z nanoparticle (NP)-enhanced photon radiotherapy is developed and tested in silico for the medical exemplar of neoadjuvant (preoperative) breast cancer MV photon radiotherapy. Two differ
...
Mechanistic DNA damage simulations in Geant4-DNA Part 2
Electron and proton damage in a bacterial cell
We extended a generic Geant4 application for mechanistic DNA damage simulations to an Escherichia coli cell geometry, finding electron damage yields and proton damage yields largely in line with experimental results. Depending on the simulation of radical scavenging, electrons do
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
Mechanistic DNA damage simulations in Geant4-DNA part 1
A parameter study in a simplified geometry
Mechanistic modelling of DNA damage in Monte Carlo simulations is highly sensitive to the parameters that define DNA damage. In this work, we use a simple testing geometry to investigate how different choices of physics models and damage model parameters can change the estimation
...
The advancement of multidisciplinary research fields dealing with ionising radiation induced biological damage – radiobiology, radiation physics, radiation protection and, in particular, medical physics – requires a clear mechanistic understanding of how cellular damage is induce
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...
The authors regret having incorrectly written in equation (7) that the fraction of surviving cells (SF) is obtained using the natural logarithm of the negative value of the number of lethal lesions Lf. The natural logarithm must be replaced by the exponential function as follows:
...