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Discovering cancer pathways

By inferring combinatorial association logic

Poster - J. de Ridder, J. de Ridder, J.J. Bot, Jaap Kool, Anthony Uren, L.F.A. Wessels, L.F.A. Wessels, M.J.T. Reinders

In this study, 43 tumors that were induced by retroviral insertional mutagenesis are expression profiled, resulting in a dataset for which both the initiating events (the viral integration sites) as well as the consequent expression profiles are available. To capture complex asso ...

Identificaton of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach

Journal article - C.N. Klijn, J.J. Bot, D.J. Adams, M.J.T. Reinders, L.F.A. Wessels, J Jonkers

A pathway approach to align regulatory-metabolic networks

Conference paper - Y. Li, J.J. Bot, M.J.T. Reinders, D. de Ridder

Inferring combinatorial association logic networks in multimodal genome-wide screens

Journal article - J. de Ridder, A Gerrits, J.J. Bot, G de Haan, M.J.T. Reinders, L.F.A. Wessels

Ibidas: querying flexible data structures to explore heterogeneous bioinformatics data

Conference paper - M. Hulsman, J.J. Bot, A.P. de Vries, M.J.T. Reinders

Mutational genomics for cancer pathway discovery

Conference paper - J. de Ridder, J Kool, M.J.T. Reinders, A.G. Uren, J.J. Bot, J de Jong, AG Rust, A Berns, M van Lohuizen, D.J. Adams, L.F.A. Wessels

CytoscapeRPC: a plugin to create, modify and query Cytoscape networks from scripting languages

Journal article - J.J. Bot, M.J.T. Reinders

RCytoscape: tools for exploratory network analysis

Journal article - PT Shannon, M Grimes, B Kutlu, J.J. Bot, DJ Galas

J.J. Bot

Authored