R. Ghorbani
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1
Unmasking the Unexpected
Towards Reliable Time Series Anomaly Detection
However, the analysis of time series data introduces challenges. For instance, label scarcity arises because labeling health anomalies requires expert input, which is often infeasible for large datasets. Inter-subject variability becomes a concern as physiological patterns differ significantly across individuals, complicating model generalization. Furthermore, temporal dependencies in time series data add complexity, as observations are sequentially related and anomalies may not manifest as isolated points but as patterns or sequences deviating from normal behavior. Detecting subtle anomalies, minor deviations that accumulate over time but may signal early-stage conditions, becomes particularly challenging due to their resemblance to normal temporal variations and noise in the data. For example, a gradual change in heart rate variability might indicate the onset of an irregular rhythm but could easily blend into inherent variability if not carefully analyzed. Moreover, evaluation metrics for time series data are insufficient, failing to capture the temporal complexities of real-world applications. Consequently, conventional metrics can misrepresent model performance, leading to unreliable or misleading assessments.
This thesis addresses these challenges by advancing time series anomaly detection through innovative methodologies. A key focus is on addressing the limitations of existing evaluation metrics by introducing new evaluation metrics to better capture temporal complexities, ensuring reliable and meaningful performance assessments. Beyond evaluation, this thesis is guided by several core principles to address the challenges inherent in time series data analysis. Central to this is the use of unsupervised representation learning to tackle label scarcity and variability, enabling robust feature extraction from unlabeled data while maintaining generalizability. Finally, the thesis develops strategies for increasing sensitivity to subtle anomalies, providing effective solutions for identifying small yet significant deviations in complex datasets. Together, these contributions present a comprehensive framework for improving anomaly detection systems across diverse applications, bridging theoretical advancements with practical, real-world needs. ...
However, the analysis of time series data introduces challenges. For instance, label scarcity arises because labeling health anomalies requires expert input, which is often infeasible for large datasets. Inter-subject variability becomes a concern as physiological patterns differ significantly across individuals, complicating model generalization. Furthermore, temporal dependencies in time series data add complexity, as observations are sequentially related and anomalies may not manifest as isolated points but as patterns or sequences deviating from normal behavior. Detecting subtle anomalies, minor deviations that accumulate over time but may signal early-stage conditions, becomes particularly challenging due to their resemblance to normal temporal variations and noise in the data. For example, a gradual change in heart rate variability might indicate the onset of an irregular rhythm but could easily blend into inherent variability if not carefully analyzed. Moreover, evaluation metrics for time series data are insufficient, failing to capture the temporal complexities of real-world applications. Consequently, conventional metrics can misrepresent model performance, leading to unreliable or misleading assessments.
This thesis addresses these challenges by advancing time series anomaly detection through innovative methodologies. A key focus is on addressing the limitations of existing evaluation metrics by introducing new evaluation metrics to better capture temporal complexities, ensuring reliable and meaningful performance assessments. Beyond evaluation, this thesis is guided by several core principles to address the challenges inherent in time series data analysis. Central to this is the use of unsupervised representation learning to tackle label scarcity and variability, enabling robust feature extraction from unlabeled data while maintaining generalizability. Finally, the thesis develops strategies for increasing sensitivity to subtle anomalies, providing effective solutions for identifying small yet significant deviations in complex datasets. Together, these contributions present a comprehensive framework for improving anomaly detection systems across diverse applications, bridging theoretical advancements with practical, real-world needs.
Photoplethysmography (PPG) signals, typically acquired from wearable devices, hold significant potential for continuous fitness-health monitoring. In particular, heart conditions that manifest in rare and subtle deviating heart patterns may be interesting. However, robust and reliable anomaly detection within these data remains a challenge due to the scarcity of labeled data and high inter-subject variability. This paper introduces a two-stage framework leveraging representation learning and personalization to improve anomaly detection performance in PPG data. The proposed framework first employs representation learning to transform the original PPG signals into a more discriminative and compact representation. We then apply three different unsupervised anomaly detection methods for movement detection and biometric identification. We validate our approach using two different datasets in both generalized and personalized scenarios. Our results demonstrate significant improvements: for movement detection, in the generalized scenario, AUCs improved from barely 0.5 to above 0.9 with representation learning. Importantly, inter-subject variability was substantially reduced, from around 0.4 to below 0.1. In the personalized scenario, AUCs became close to 1.0, with variability further reduced to below 0.05, indicating the effectiveness of both representation learning and personalization for anomaly detection in PPG data. Similar enhancements were observed in biometric identification, emphasizing how our approach can minimize inter-subject variability and enhance PPG-based health monitoring systems.
PATE
Proximity-Aware Time Series Anomaly Evaluation
With the progress of sensor technology in wearables, the collection and analysis of PPG signals are gaining more interest. Using Machine Learning, the cardiac rhythm corresponding to PPG signals can be used to predict different tasks such as activity recognition, sleep stage detection, or more general health status. However, supervised learning is often limited by the amount of available labeled data, which is typically expensive to obtain. To address this problem, we propose a Self-Supervised Learning (SSL) method with a pretext task of signal reconstruction to learn an informative generalized PPG representation. The performance of the proposed SSL framework is compared with two fully supervised baselines. The results show that in a very limited label data setting (10 samples per class or less), using SSL is beneficial, and a simple classifier trained on SSL-learned representations outperforms fully supervised deep neural networks. However, the results reveal that the SSL-learned representations are too focused on encoding the subjects. Unfortunately, there is high inter-subject variability in the SSL-learned representations, which makes working with this data more challenging when labeled data is scarce. The high inter-subject variability suggests that there is still room for improvements in learning representations. In general, the results suggest that SSL may pave the way for the broader use of machine learning models on PPG data in label-scarce regimes.
Due to the development of biomedical equipment and healthcare level, especially in the Intensive Care Unit (ICU), a considerable amount of data has been collected for analysis. Mortality prediction in the ICUs is considered as one of the most important topics in the healthcare data analysis section. A precise prediction of the mortality risk for patients in ICU could provide us with valuable information about patients' lives and reduce costs at the earliest possible stage. This paper aims to introduce a new hybrid predictive model using the Genetic Algorithm as a feature selection method and a new ensemble classifier based on the combination of Stacking and Boosting ensemble methods to create an early mortality prediction model on a highly imbalanced dataset. The SVM-SMOTE method is used to solve the imbalanced data problem. This paper compares the new model with various machine learning models to validate the efficiency of the introduced model. The achieved results using the shuffle 5-fold cross-validation and random hold-out methods indicate that the new hybrid model has the best performance among other classifiers. Additionally, the Friedman test is applied as a statistical significance test to examine the differences between classifiers. The results of the statistical analysis prove that the proposed model is more effective than other classifiers. Furthermore, the proposed model is compared to APACHE and SAPS scoring systems and is benchmarked against state-of-the-art predictive models applied to the MIMIC dataset for experimental validation and achieved promising results as it outperformed the state-of-the-art models.