The research was conducted looking into the possibilities of local manufacturing and assembly of medical devices in low and middle-income countries. Desktop research and expert interviews were conducted to learn the operations of medical devices (and other product) manufacturers. The interview process validated the literature study and also brought to light some new information on how medical device manufacturing (both local and international) operates. The research resulted in key drivers and inhibitors that companies need to consider when shifting their operations (or not) to low and middle-income countries.