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S. Hinrichs-Krapels

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Journal article (2026) - Noa E.M. Kolpa, Roel Kamerling, Degu Jerene, Ajay Bailey, Koiwah Koi-Larbi, Tessa Roseboom, Wieger Voskuijl, Isabelle L. Lange, Veronique Filippi, Indah K. Murni, Titus K. Beyuo, Manouk A.W. van de Klundert, Sreeparna Chattopadhyay, Saba Hinrichs-Krapels, Joyce L. Browne, Emmanuel Ojo, Mulatu Biru, Igna Bonfrer, Bregje de Kok, Godelieve van Heteren, Kitty W.M. Bloemenkamp, Beatrijs Stikkers-Muller
Review (2026) - Myrthe van der Zanden, Saba Hinrichs-Krapels, Christa Niehot, Anna Teeuw, Swasti Madan, Naomi van der Linden
Introduction There is a large and increasing shortage of nursing staff. To alleviate this problem, healthcare systems should prioritize healthcare interventions that improve nurse retention over healthcare interventions that reduce it or leave it unchanged. One way to do so is to evaluate interventions on their anticipated impact on nurse intention-to-stay, which is an important precursor of retention. An overview of available instruments to quantify nurse intention-to-stay is lacking, resulting in researchers re-inventing the wheel. This review aims to fill this gap. Methods A systematic literature search was performed in the databases Medline ALL via Ovid, Embase.com, Web of Science Core Collection, CINAHL Plus, PsycINFO, the Cochrane Central Register of Controlled Trials via Wiley, and Google Scholar (200 highest-ranked references only). The search string consisted of terms and associated synonyms for 1) nursing staff, 2) personnel intent to stay/leave, and 3) surveys. Articles were included when there was a quantitative method mentioned for measuring the intention of nurses to stay or quit nursing and/or their job/position/organization. Information was extracted on the year of publication, study design, study population, number of participants, instrument used for measuring intention-to-stay, and whether the instrument was focused on leaving the job, organization, or profession. In addition, we checked whether the instrument was used to evaluate the (expected or realized) impact of an intervention and if an association was determined between intention-to-stay (measured through the instrument) and retention. The protocol was not registered. Results 967 articles fulfilled our inclusion criteria, most of which were published in recent years. A total of 485 instruments were found. Nine regularly used instruments were identified, differing in their respective popularity over time, their size, the population for which they were developed and the strength of their link to actual retention. Notably, compared with the large body of literature on nurse intention-to-stay generally, the number of studies specifically measuring the impact of an intervention on nurse intention-to-stay is limited (n=20). Most of these intervention studies focused on changes in nurse training/mentorship or mental health support. Discussion & conclusion Many different instruments exist to measure nurses' intention-to-stay. To add to our identified instruments, a comparative study is needed to identify which instrument offers the strongest predictive value for nurse retention. The absence of studies specifically evaluating the impact of interventions on nurses' intention-to-stay creates a critical gap in understanding how health interventions influence retention. Funding Dutch Research Council, 406.XS.04.151. ...

Advancing community and health system resilience through intersectionality theory

Current approaches to health system resilience tend to prioritize system-level outcomes (e.g. functionality) while overlooking key underlying social processes, contexts, and power-laden interactions through which resilience is produced. When community resilience is subsumed under health system resilience, without attending to distinct contextual factors, it can lead to fragmented approaches or maladaptive outcomes that misalign with the resilience of communities. Therefore, resilience approaches need to include additional methods that incorporate analyses of power structures and context. We propose intersectionality theory as a methodological lens to investigate the underlying social processes and power dynamics that shape community resilience and health system resilience interactions. An intersectionality approach prompts researchers to distinguish how resilience capacity is derived through the involvement of community actors, their unique intersecting social identities, and their lived experiences. Including an intersectional lens in resilience approaches provides researchers with the tools to identify points of practical constraints that arise at the intersection of communities and health systems, with particular attention on the burdens that are placed on community actors. ...
Journal article (2026) - Kelly Vos, J. Theresia van Essen, Erwin Ista, Lonneke M. Staals, Saba Hinrichs-Krapels
Introduction: Mathematical and optimisation models are frequently used to improve hospital planning and capacity management. However, the resulting model-derived solutions are rarely evaluated for their adoption within the real-world context of a hospital. Objectives: In this study, we share our experience of an interdisciplinary collaboration between operations research/management science and implementation science, as one way of bridging the gap between technically sound solutions and their practical, sustainable use in healthcare. Methodology: We applied implementation science prospectively to anticipate adoption implications at the design stage of a scheduling tool. Specifically, we used the Consolidated Framework for Implementation Research (CFIR) to identify anticipated barriers and facilitators for adopting a mathematically optimised surgery blueprint schedule within a children’s hospital. Results: Identified anticipated facilitators included strong staff motivation to improve schedules, as well as positive perceptions of an objectively designed mathematical scheduling tool. Barriers included resistance to change among some staff and the demand for more evidence of the schedule’s benefits prior to implementation. We identified a strong culture of retaining autonomy in scheduling decisions, as well as operational adjustments made to current scheduling tools. Practical implications: Applying CFIR prospectively demonstrated how implementation science frameworks could provide a structured way to anticipate adoption challenges and align technical solutions with organisational realities. ...

Addressing power, ownership, and invisible labour

Journal article (2026) - Robyn Curran, Saba Hinrichs-Krapels, Goodman Makanda, Ruth Cornick, Zamasomi Luvuno, Inge Petersen, Naomi S. Levitt, Lara Fairall
Journal article (2026) - Tamara Hoveling, Jelle Ijzenbrandt, Saba Hinrichs-Krapels, Linda Ritzen, Wichor M. Bramer, Erik van Raaij, Jeremy Faludi, Conny Bakker, Jan Carel Diehl
Background
The healthcare sector contributes substantially to environmental pollution, affecting ecosystems and public health. Circular economy (CE) strategies offer potential solutions, but existing frameworks provide limited guidance for healthcare, overlooking factors such as infection control, decontamination, and staff workload.

Methods
We developed the Circular Healthcare Flows visual, a taxonomy of CE strategies for medical devices, using observations in sterilization departments, recycling facilities, and manufacturing plants; 21 expert interviews; and a systematic review of 1104 studies (68 full-text reviews). Additional stakeholder feedback validated and refined the taxonomy.

Findings
The taxonomy identifies 13 CE strategies—refuse, replace, rethink, reduce, reuse, maintain, repair, refurbish, remanufacture, repurpose, recycle, renew, and recover—and organizes them in a healthcare-specific framework. Iterative feedback ensured that the taxonomy is clear, practically applicable, and addresses sector-specific regulatory, clinical, and operational constraints.

Interpretation
The Circular Healthcare Flows visual provides a practical tool to standardize terminology and guide the implementation of CE strategies in healthcare. By offering conceptual structure and actionable guidance, it supports informed decision-making, facilitates collaboration among stakeholders, and encourages consistent application of circular strategies across the sector.

Funding
IJzenbrandt was partially funded by Erasmus University Rotterdam and the Health and Technology Convergence Alliance of TU Delft, Erasmus MC, and Erasmus University Rotterdam. Hoveling was funded through the DiCE project (EU grant agreement no. 101060184). Opinions expressed are those of the authors and do not necessarily reflect those of the EU or REA. ...
Journal article (2025) - Josephine Wagenaar, Ron Van Beek, Henrike Pas, Martijn Suurveld, Naomi Van Der Linden, Julia Broos, Maaike Kleinsmann, Saba Hinrichs, H. Rob Taal
Background: Telemedicine in neonatal care (TeleNeonatology) has the potential to improve neonatal outcomes, address capacity challenges and influence the emotional burden on parents. TeleNeonatology allows for real-time audiovisual communication between healthcare providers at different neonatal intensive care units (NICUs). Despite the high potential for multiple neonatal use-cases, TeleNeonatology is primarily being used for neonatal resuscitation and has yet to be widely implemented in Europe. Our study aims to evaluate both implementation strategies and effectiveness of TeleNeonatology in a pilot study in The Netherlands.

Methods: A pre-post implementation study with hybrid type III design will be conducted from 1 January 2023 to 31 December 2024. The year 2023 will serve as a baseline period pre-implementation. From 1 January 2024, a TeleNeonatology device will be integrated within all communication between the NICU-level IV of the Erasmus MC hospital and the NICU-level II at Amphia Hospital. Outcomes of the implementation of the TeleNeo programme will be evaluated using a mixed-methods approach evaluating implementation outcomes, service outcomes and client outcomes. Feasibility, the primary implementation outcome, will be evaluated via a validated questionnaire for parents and personnel. Secondary implementation outcomes will be barriers and facilitators of implementation, based on semi-structured interviews and focus groups. A cost minimisation analysis, using decision trees, will be evaluated as service outcomes. Client outcomes will be assessed via parent-reported transfer experience questionnaires and interviews and the clinical outcomes NICU-level III transfer rate and length of stay.

Ethics and dissemination: This study was reviewed by the Medical Ethical Committee of the Erasmus Medical Centre, who confirmed that the rules laid down in the Medical Research Involving Human Subjects Act do not apply (identification number: MEC-2023–0561). Results will be published in peer-reviewed journals in two separate scientific articles: the primary evaluation and the cost evaluation. ...
Purpose (stating the main purposes and research question): Anthropogenic resource use contributes to pollution, violent conflict over scarce resources, loss of biodiversity, and diminished quality of life for humans. Moreover, the “safe” amount of carbon dioxide—350 parts per million—has been exceeded. The health care industry is responsible for 4–5% of total world emissions,[i] which is similar to the global food sector.[ii] Health care carbon emissions come from health care infrastructures, supply chains and health care delivery. Increasingly, health care delivery is reliant on technologies which require the use of artificial intelligence to provide supportive care, such as triage algorithms, electronic patient records, and robotics.[iii] While these technological innovations have advanced health care significantly, they also contribute to the negative effects on the environment, among others, through carbon emissions. The environmental impacts of artificial intelligence (AI) in health care—in particular—are understudied. This research seeks to fill this gap. Methods: Our team ran an exploratory search in Scopus and PubMed to identify studies that integrate environmental sustainability, artificial intelligence, and health. Results: Our research initially yielded 735 studies. 77 of these studies focused on an environmental concern of a health technology or AI-application in a health care setting, but most of the articles in this subset addressed lowering energy consumption of a specific technology, such as a sensor or monitoring technology. Conclusions: While there have been studies looking at AI in health care; sustainability in AI; and sustainability in health care, little attention has been paid to the interface between all three. [i] Karliner, J., Slotterback, S., Boyd, R., Ashby, B., & Steele, K. 2019. Health Care’s Climate Footprint: How the Health Sector Contributes to the Global Climate Crisis and Opportunities for Action Healthcare Without HarmARUP; September. [ii] Pichler, P. P., Jaccard, I. S., Weisz, U., & Weisz, H. 2019 International Comparison of Health Care Carbon Footprints, Environmental Research Letters 14, no. 6: 064004. [iii] Khaliq, Abdul, Ali Waqas, Qasim Ali Nisar, Shahbaz Haider, and Zunaina Asghar. 2022. Application of AI and robotics in hospitality sector: A resource gain and resource loss perspective. Technology in Society 68: 101807. ...
Purpose
Properly functioning health systems globally require medical devices and equipment for vital care. Despite promising innovations, many medical devices face adoption barriers such as regulatory issues, interoperability and data exchange challenges. In low-resource settings, contextual factors influencing adoption and diffusion have not been synthesized into an overview to guide future medical device and equipment suppliers. Our study provides a scientific inventory of frameworks, theories, models, and guidelines describing the adoption and diffusion of medical devices and equipment in low-resource settings.

Methods
We searched both the PubMed and Scopus databases to identify studies within the health and broader non-health domains. Our search yielded 2.124 results after de-duplication. Extended attributes on the type of the paper, adoption and diffusion focus, medical devices and equipment use cases, and country settings revealed patterns of underpinning and emerging frameworks for adoption and diffusion.

Results
We included 28 studies in our review. The most researched device types were telemedicine, telehealth, m-health, and e-health. Among a larger variety, the most utilized underpinning frameworks were the Diffusion of Innovation Framework, and the Technology Acceptance Model. These frameworks led to the development of emerging models, such as a modified version based on Kifle’s Adoption Model or the Intervention-Context-Actors-Mechanism-Outcome Model.

Conclusions
Our findings offer initial insights for further research in identifying mechanisms for improving access to and utilization of medical devices and equipment in low-resource settings. Researchers can use this comprehensive review to guide continued research, addressing gaps in theoretical understanding and empirical evidence on medical device adoption and diffusion in low-resource settings. ...

A protocol for a 5-year multi-sited interdisciplinary research project into preparedness of healthcare for floods in the Netherlands

Journal article (2025) - Robert A.J. Borst, Yared Abayneh Abebe, Sebastiaan N. Jonkman, Roland Bal, Karin van Vuuren, Julien Magana, Bert de Graaff, Saba Hinrichs-Krapels, Bas Kolen, Maria Pregnolato, Anja Schreijer, Tina Comes
Introduction: The 2021 European floods in Germany, Belgium, and the Netherlands significantly impacted healthcare. With climate change increasing flood risks, healthcare preparedness is essential. Floods affect healthcare directly and indirectly by disrupting patient access, damaging infrastructure and impeding care continuity. Our interdisciplinary research in the Netherlands systematically assesses flood impacts on healthcare, optimises disaster preparedness, patient logistics, and continuity and explores crisis governance, incorporating lessons from coronavirus disease-2019 (COVID-19). Methods: Our multi-sited, interdisciplinary project titled “Pandemic lessons for flood disaster preparedness” includes literature reviews on: (i) the (in) direct impacts of floods on healthcare, (ii) disaster decision-making strategies and (iii) patient logistics during crises. Empirically, ethnographic methods (interviews, focus groups, document analyses, and observations) will: (a) assess hospital flood preparedness, (b) explore decision-making and crisis management strategies and (c) analyse the dynamics of health system governance during floods. Data from these sources and flood scenarios will inform models on healthcare impacts and decision-making, culminating in a simulation game for research and training. Discussion: This study offers a comprehensive, interdisciplinary approach to understanding and improving healthcare system preparedness for floods. By integrating diverse fields such as healthcare governance, disaster risk management, logistics and hydraulic engineering, we provide a unique lens on resilience. A key strength is the incorporation of lessons from the COVID-19 pandemic, allowing us to draw parallels between pandemic response and flood preparedness. In addition, our simulation game serves as a robust tool for translating knowledge into practice. However, the study’s reliance on collaboration with busy healthcare and disaster response professionals may limit engagement. Moreover, the absence of direct public and patient involvement in the research design, though partially mitigated by engaging representative organizations, presents a potential limitation. Lastly, the challenge of obtaining real-time data from flood events could introduce recall bias, but triangulation of various data sources aims to address this issue. Despite these challenges, the study’s integration of long-term data from recent floods and focus on healthcare-specific crisis governance provides valuable insights for improving disaster preparedness. ...

A simulation study based on clinical data in the Netherlands

Journal article (2025) - Josephine H.L. Wagenaar, Alexander Dietz, Yilin Huang, Irwin K.M. Reiss, Jasper V. Been, Jessie Spaan, René F. Kornelisse, Hendrik Rob Taal, Saba Hinrichs-Krapels
Objective To analyse the impact of selected neonatal care interventions on regional care capacity.Design Discrete event simulation modelling based on clinical data.
Setting Neonatal care in the southwest of the Netherlands, consisting of one tertiary-level neonatal intensive care unit (NICU), four hospitals with high-care neonatal (HCN) wards and six with medium-care neonatal (MCN) wards.
Participants 44 461 neonates admitted to at least one hospital within the specified region or admitted outside of the region but with a residential address inside the region between 2016 and 2021.
Interventions The impact of three interventions was simulated: (1) home-based phototherapy for hyperbilirubinaemia, (2) oral antibiotic switch for culture-negative early onset infection and (3) changing tertiary-level NICU admission guidelines.
Main outcome measure Regional neonatal capacity defined as: (1) occupancy per ward level, (2) required operational beds per ward level to provide care to all inside region patients at maximum 85% occupancy, (3) proportion rejected, defined as outside region transfers due to no capacity to provide local care and (4) the weekly rejections in relation to occupancy to provide a combined analysis.
Results In the current situation, with many operational beds closed due to nurse shortages, occupancy was extremely high at the NICU and HCNs (respectively 91.7% (95% CI 91.4 to 92.0) and 98.1% (95% CI 98.0 to 98.2)). The number of required beds exceeded available beds, resulting in >20% rejections for both NICU and HCN patients. Although the three interventions individually demonstrated effect on capacity, clinical impact was marginal. In combination, NICU occupancy was reduced below the 85% government recommendation at the cost of an increased burden for HCNs, highlighting the need for redistribution to MCNs.
Conclusion Our model confirmed the severity of current neonatal capacity strain and demonstrated the potential impact of three interventions on regional capacity. The model showed to be a low-cost and easy-to-use method for regional capacity impact assessment and could provide the basis for making informed decisions for other interventions and future scenarios, supporting data-driven neonatal capacity planning and policy development.
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Journal article (2025) - Josephine H.L. Wagenaar, Julia Broos, Saba Hinrichs-Krapels, Irwin K.M. Reiss, H. Rob Taal, Ron H.T. van Beek, Henrike Pas, Martijn Suurveld, Anne Jacobs, Fredrik Bodell, Sylvia A. Obermann-Borst, Florian Cassel, Maaike S. Kleinsmann
Background: Real-time audiovisual communication between healthcare providers (HCP) at different hospitals (TeleNeonatology) can improve neonatal outcomes, address capacity challenges, and reduce emotional burden on parents. Despite its potential, TeleNeonatology has yet to be widely implemented in routine clinical care, partly due to non-optimal integration into care pathways and working routines. To provide insights for further adoption, this study presents the evaluation of a pilot in the Netherlands. Methods: A prospective hybrid type III effectiveness-implementation study was conducted in 2024. During the pilot, a TeleNeo program facilitated both acute and elective communication between Erasmus MC NICU-level IV and Amphia NICU-level II. The TeleNeo program was developed and continuously improved during the pilot using co-creation with HCP and parents to enable embedding in care pathways and working routines. A mixed-methods approach was used for evaluation. The primary outcome was a validated 21-item usability questionnaire with five-points Likert Scale questions for parents (n = 50) and HCP (n = 85). Implementation determinants were evaluated with semi-structured interviews and surveys. Effectiveness was measured via parent reported experiences, and clinical outcomes length-of-stay and transfer rate. Results: Twelve months of implementation led to 99 consultations for 50 patients and families, including 33 acute patients, possibly in need of an acute transfer. Evaluation showed high feasibility and adoption. Usability was high among parents (n = 26, median score 5 [interquartile rage: 4–5]) and HCP (n = 48, median score 5 [interquartile range 4–5]). Parents valued rapid expert availability, involvement in transfer decisions, and experienced shared care between the NICUs. HCP observed quick and approachable communication, quicker medical decisions, improved quality of care, and smoother transitions between NICUs. Nurses were able to be more pro-active. In 18% (6/33) of acute cases transfers were perceived to be prevented. HCP highlighted TeleNeo’s influence on the local teams’ autonomy, communication styles, and financial aspects as important barriers in interviews (n = 12) and questionnaires (n = 65). Conclusions: Pilot implementation showed high feasibility of our TeleNeo program, enabling shared care at the optimal location for our patients. Our findings will guide a robust strategy for implementation in the Southwest of the Netherlands, enhancing neonatal care, parental satisfaction and nursing experience. ...

A scoping review of actors, transport modes and decision problems

Review (2025) - Julien Magana, Saba Hinrichs-Krapels, Wichor Bramer, Tina Comes
Purpose
Sudden-onset disasters impact the health and well-being of millions of people each year. Typically, a sudden-onset disaster will lead to a surge of patients that require immediate acute care, even though health infrastructure and resources may be destroyed or not accessible. The challenge of patient flow logistics is transporting those in need of acute care rapidly to locations where they can be treated. The fields and disciplines tackling these challenges, therefore, span from disaster-related to health-related logistics, but it is not known whether and how research and approaches across these fields align. This study aims to scope this emergent field, identify research gaps and develop a conceptual framework that bridges the disaster-related and health-related logistics literature.
Design/methodology/approach
This paper follows a scoping review protocol. The authors screened an initial 8,491 papers, of which 127 were retained for a full-text review. Analyzing these papers, the authors map out the key concepts such as actors, locations, transportation modes and decision problems used in the literature. The study identifies research gaps and synthesize the findings into a conceptual framework to guide future research.
Findings
This review identified four gaps in the existing literature: (1) The literature focuses primarily on earthquakes and terrorist attacks, limited attention is given to other sudden-onset disaster types despite their frequency; (2) The literature focuses on formal actors such as health providers or civil protection bodies, while communities are largely portrayed as passive patients or victims; (3) Actors are largely assumed to follow standardized protocols, often ignoring emergent roles or behavioral changes typical for sudden-onset disasters; (4) Objectives predominantly relate to either efficiency or effectiveness, neglecting fairness and multiobjective problems.
Originality/value
To the best of the authors’ knowledge, this scoping review is the first to explore the different aspects of patient logistics in sudden-onset disasters by bridging the disaster-related and health-related literature.
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Background: Health systems worldwide struggled to obtain sufficient personal protective equipment (PPE) and ventilators during the COVID-19 pandemic due to global supply chain disruptions. Our study’s aim was to create a proof-of-concept model that would simulate the effects of supply strategies under various scenarios, to ultimately help decision-makers decide on alternative supply strategies for future similar health system related crises. Methods: We developed a system dynamics model that linked a disease transmission model structure (susceptible, exposed, infectious, recovered (SEIR)) with a model for the availability of critical supplies in hospitals; thereby connecting care demand (patients’ critical care in hospitals), with care supply (available critical equipment and supplies). To inform the model structure, we used data on critical decisions and events taking place surrounding purchase, supply, and availability of PPE and ventilators during the first phase of the COVID-19 pandemic within the English national health system. We used exploratory modelling and analysis to assess the effects of uncertainties on different supply strategies in the English health system under different scenarios. Strategies analysed were: (i) purchasing from the world market or (ii) through direct tender, (iii) stockpiling, (iv) domestic production, (v) supporting innovative supply strategies, or (vi) loaning ventilators from the private sector. Results: We found through our exploratory analysis that a long-lasting shortage in PPE and ventilators is likely to be apparent in various scenarios. When considering the worst-case scenario, our proof-of-concept model shows that purchasing PPE and ventilators from the world market or through direct tender have the greatest influence on reducing supply shortages, compared to producing domestically or through supporting innovative supply strategies. However, these supply strategies are affected most by delays in their shipment time or set-up. Conclusion: We demonstrated that using a system dynamics and exploratory modelling approach can be helpful in identifying the purchasing and supply chain strategies that contribute to the preparedness and responsiveness of health systems during crises. Our results suggest that to improve health systems’ resilience during pandemics or similar resource-constrained situations, purchasing and supply chain decision-makers can develop crisis frameworks that propose a plan of action and consequently accelerate and improve procurement processes and other governance processes during health-related crises; implement diverse supplier frameworks; and (re)consider stockpiling. This proof-of-concept model demonstrates the importance of including critical supply chain strategies as part of the preparedness and response activities to contribute to health system resilience. ...

A scoping review of empirical studies and reviews

BACKGROUND: Prompted by recent shocks and stresses to health systems globally, various studies have emerged on health system resilience. Our aim is to describe how health system resilience is operationalised within empirical studies and previous reviews. We compare these to the core conceptualisations and characteristics of resilience in a broader set of domains (specifically, engineering, socio-ecological, organisational and community resilience concepts), and trace the different schools, concepts and applications of resilience across the health literature. METHODS: We searched the Pubmed database for concepts related to 'resilience' and 'health systems'. Two separate analyses were conducted for included studies: a total of n = 87 empirical studies on health system resilience were characterised according to part of health systems covered, type of threat, resilience phase, resilience paradigm, and approaches to building resilience; and a total of n = 30 reviews received full-text review and characterised according to type of review, resilience concepts identified in the review, and theoretical framework or underlying resilience conceptualisation. RESULTS: The intersection of health and resilience clearly has gained importance in the academic discourse with most papers published since 2018 in a variety of journals and in response to external threats, or in reference to more frequent hospital crisis management. Most studies focus on either resilience of health systems generally (and thereby responding to an external shock or stress), or on resilience within hospitals (and thereby to regular shocks and operations). Less attention has been given to community-based and primary care, whether formal or informal. While most publications do not make the research paradigm explicit, 'resilience engineering' is the most prominent one, followed by 'community resilience' and 'organisational resilience'. The social-ecological systems roots of resilience find the least application, confirming our findings of the limited application of the concept of transformation in the health resilience literature. CONCLUSIONS: Our review shows that the field is fragmented, especially in the use of resilience paradigms and approaches from non-health resilience domains, and the health system settings in which these are used. This fragmentation and siloed approach can be problematic given the connections within and between the complex and adaptive health systems, ranging from community actors to local, regional, or national public health organisations to secondary care. Without a comprehensive definition and framework that captures these interdependencies, operationalising, measuring and improving resilience remains challenging. ...

A qualitative study based on staff experiences and observations

Journal article (2023) - S. Hinrichs-Krapels, Lazarus Tombo, Harriet Boulding, Edith D. Majonga, Carole Cummins, Semira Manaseki-Holland
Despite its fundamental role in diagnostic and curative care, radiology has been described as a neglected essential service in many low and middle-income countries (LMICs). Previous studies have demonstrated basic equipment and infrastructure shortages in LMIC settings, but no studies to date have gone further in understanding the perceptions and experiences of staff delivering radiology services, as a way of identifying their perspectives on barriers and facilitators for delivering services, and the potential for where improvements can be made. Our qualitative study aimed to: (a) identify barriers for delivering radiology services, and (b) suggest potential facilitators for improvement of radiology service delivery in the Zimbabwean context; from the perspective of radiology staff. We conducted semi-structured interviews (n = 13) and three focus groups (n = 24 radiographers), followed by four half- to full- days of field observations to validate insights from the interviews and focus groups in all three public hospitals and one private hospital in the Harare metropolitan area. Our study identified four main barriers for delivering radiology services: (i) poor basic infrastructure, equipment, and consumables; (ii) suboptimal equipment maintenance; (iii) shortage of radiology staff and skills development; and (iv) lack of wider integration and support for radiology services. We also identified a strong sense of motivation among staff to keep radiology services, pointing to what may be an enabler and facilitator for improving radiology services. These findings point to potential risks to patient safety and quality of delivering radiology services. More importantly, we found a strong sense of personal motivation displayed by the staff, suggesting there is the potential to maintain and improve existing practices, but this would require investments to train and remunerate more radiology staff, as well as investing in continuing professional development. ...

The radical and incremental challenges in the technology ecosystem

Journal article (2022) - Saba Hinrichs-Krapels, Jan-Carel Diehl, Nicole Hunfeld, Erik van Raaij
Review (2022) - Saba Hinrichs-Krapels, Bor Ditewig, Harriet Boulding, Anastasia Chalkidou, Jamie Erskine, Farhad Shokraneh
Objectives To systematically review academic literature for studies on any processes, procedures, methods or approaches to purchasing high-cost medical devices and equipment within hospitals in high-income countries. Methods On 13 August 2020, we searched the following from inception: Cost-Effectiveness Analysis Registry, EconLit and ProQuest Dissertations & Theses A&I via ProQuest, Embase, MEDLINE, and MEDLINE in Process via Ovid SP, Google and Google Scholar, Health Management and Policy Database via Ovid SP, IEEE Xplore Digital Library, International HTA Database, NHS EED via CRD Web, Science Citation Index-Expanded, Conference Proceedings Citation Index-Science, and Emerging Sources Citation Index via Web of Science, Scopus, and Zetoc conference search. Studies were included if they described the approach to purchasing (also known as procurement or acquisition) of high-cost medical devices and/or equipment conducted within hospitals in high-income countries between 2000 and 2020. Studies were screened, data extracted and results summarised in tables under themes identified. Results Of 9437 records, 24 were included, based in 12 different countries and covering equipment types including surgical robots, medical imaging equipment, defibrillators and orthopaedic implants. We found heterogeneity in methods and approaches; including descriptions of processes taking place within or across hospitals (n=14), out of which three reported cost savings; empirical studies in which hospital records or participant data were analysed (n=8), and evaluations or pilots of proposed purchasing processes (n=2). Studies emphasise the importance of balancing technical, financial, safety and clinical requirements for device selection through multidisciplinary involvement (especially clinical engineers and clinicians) in decision-making, and the potential of increasing evidence-based purchasing decisions using approaches such as hospital-based health technology assessments, ergonomics and device 'user trials'. Conclusions We highlight the need for more empirical work that evaluates purchasing approaches or interventions, and greater specificity in study reporting (eg, equipment type, evaluation outcomes) to build the evidence base required to influence policy and practice for medical equipment purchasing. Protocol registration This review was registered in Open Science Framework: Shokraneh F, Hinrichs-Krapels S, Chalkidou A et al. Purchasing high-cost medical equipment in hospitals in OECD countries: A systematic review. Open Science Framework 2021; doi:10.17605/OSF.IO/GTXN8. Available at: https://osf.io/gtxn8/ (accessed 12 February 2022). ...
Journal article (2021) - Nadine Seward, Jamie Murdoch, Martin Prince, Jane Sandall, Graham Thornicroft, Ruth Verhey, Nick Sevdalis, Charlotte Hanlon, Ricardo Araya, Wei Gao, Richard Harding, Crick Lund, Saba Hinrichs-Krapels, Rosie Mayston, Muralikrishnan Kartha
Objectives ASSET (Health System Strengthening in sub-Saharan Africa) is a health system strengthening (HSS) programme involving eight work-packages (ie, a research study that addresses a specific need for HSS) that aims to develop solutions that support high-quality care. Here we present the protocol for the implementation science (IS) theme within ASSET (ASSET-ImplmentER) that aims to understand what HSS interventions work, for whom and how, and how IS methodologies can be adapted to improve the HSS interventions within resource-poor contexts. Settings Publicly funded health facilities in rural and urban areas in in Ethiopia, South Africa, Sierra Leone, and Zimbabwe. Participants Research staff including principal investigators, coinvestigators, field staff, PhD students, and research assistants. Interventions Work-packages use a mixed-methods effectiveness-effectiveness hybrid designs. At the end of the pre-implementation phase, a workshop is held whereby the IS theme, jointly with ASSET work-packages apply IS determinant frameworks to research findings to identify factors that influence the effectiveness of delivering evidence-informed care. Determinants are used to select a set of HSS interventions for further evaluation, where work-packages also theorise selective mechanisms. In the piloting and rolling implementation phase, work-packages pilot the HSS interventions. An iterative process then begins involving evaluation, reflection and adaptation. Throughout this phase, IS determinant frameworks are applied to monitor and identify barriers/enablers to implementation. Selective mechanisms of action are also investigated. Implementation outcomes are evaluated using qualitative and quantitative methods. The psychometric properties of outcome measures including acceptability, appropriateness and feasibility are also evaluated. In a final workshop, work-packages come together, to reflect and explore the utility of the selected IS methods and provide suggestions for future use. Structured templates are used to organise and analyse common and heterogeneous patterns across work-packages. Qualitative data are analysed using thematic analysis and quantitative data are analysed using means and proportions. Conclusions We use a novel combination of IS methods at a programmatic level to facilitate comparisons of determinants and mechanisms that influence the effectiveness of HSS interventions in achieving implementation outcomes across different contexts. The study also contributes conceptual development and clarification at the underdeveloped interface of IS, HSS and global health. The ASSET-ImplementER theme is considered minimal risk as we only interview researchers involved in the different work-packages. To this effect we have received approval from King's College London Ethics Committee for research that is considered minimal risk (Reference number: MRA-20/21-21772). ...
Journal article (2021) - Nadine Seward, Charlotte Hanlon, Nick Sevdalis, Saba Hinrichs-Kraples, Crick Lund, Jamie Murdoch, Tatiana Taylor Salisbury, Ruth Verhey, Rahul Shidhaye, Graham Thornicroft, Ricardo Araya
Implementation research is a multidisciplinary field that addresses the complex phenomenon of how context influences our ability to deliver evidence-informed healthcare. There is increasing realisation of the importance of applying robust implementation research to scale-up life-saving interventions that meet health-related sustainable development goals. However, the lack of high-quality implementation research is impeding our ability to meet these targets, globally. Within implementation research, theory refers to the proposed hypothesis and/or explanation of how an intervention is expected to interact with the local context and actors to bring about change. Although there is increasing interest in applying theory to understand how and why implementation programmes work in real-world settings, global health actors still tend to favour impact evaluations conducted in controlled environments. This may, in part, be due to the relative novelty as well as methodological complexity of implementation research and the need to draw on divergent disciplines, including epidemiology, implementation science and social sciences. Because of this, implementation research is faced with a particular set of challenges about how to reconcile different ways of thinking and constructing knowledge about healthcare interventions. To help translate some of the ambiguity surrounding how divergent theoretical approaches and methods contribute to implementation research, we draw on our multidisciplinary expertise in the field, particularly in global health. We offer an overview of the different theoretical approaches and describe how they are applied to continuously select, monitor and evaluate implementation strategies throughout the different phases of implementation research. In doing so, we offer a relatively brief, user-focused guide to help global health actors implement and report on evaluation of evidence-based and scalable interventions, programmes and practices. ...