In connection with growing in applications of nanoparticles in various industrial sectors such as cosmetics and pharmaceuticals, the demand for in-line identification and characterization of nanoparticles suspended in fluids has increased. In addition to that, nanoparticles in general and nanoplastics in particular, can easily contaminate air and water resources, resulting in human health risks. Among available techniques, suspended microchannel resonators can respond to the characterization demands in terms of mass detection and concentration of nanoparticles in fluids. This technique is based on changes in resonance frequency of the suspended microchannel due to flowing of nanoparticles through the suspended hollow cantilever. In this project we aimed to characterise TUDelft made suspended microchannel resonators in terms of mass limit detection and speed of detection. We found that the lowest resolved mass can be detected by the second bending mode. This was 0.11 fg and0.38 fg using an empty and a water-filled resonator respectively, for a system bandwidth of 1000 Hz that corresponds to a system settling time of 0.37 ms. We also managed to measure a buoyant mass of 21.2 fg which is an equivalent gold nanoparticle of 130 nm in diameter, during one of the attempts to detect suspended gold nanoparticles in deionized water.