Advanced muscle-on-chip devices: Growing muscle project
M. Leeuwenburg (TU Delft - Electrical Engineering, Mathematics and Computer Science)
R.D. Krüger (TU Delft - Electrical Engineering, Mathematics and Computer Science)
W. van der Plas (TU Delft - Electrical Engineering, Mathematics and Computer Science)
M. Mastrangeli – Mentor (TU Delft - Electrical Engineering, Mathematics and Computer Science)
More Info
expand_more
Other than for strictly personal use, it is not permitted to download, forward or distribute the text or part of it, without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license such as Creative Commons.
Abstract
This report presents the design and implementation of a single-well muscle-on-a-chip device capable of displacing one of the support pillars to which muscle tissue is bound, using an electromechanical actuator. In addition to this displacement capacity, the muscle tissue can be electrically stimulated, allowing for the measurement of corresponding contraction forces via post-deflection methods. Experimental results demonstrate that the actuated support pillar can be moved by approximately 40μm per
step.