Two contrast detection sequences for bandwidth-limited intravascular ultrasound transducers

Conference paper (2012)

Authors

D. Maresca Erasmus MC
Guillaume Renaud Erasmus MC
G. van Soest Erasmus MC
Xiang Li University of Southern California
Qifa Zhou University of Southern California
K. Kirk Shung University of Southern California
N. de Jong Erasmus MC, , University of Southern California
A.F.W. van der Steen Erasmus MC, , Biomedical Engineering
Intravascular ultrasound Chirp reversal Ultraharmonic Ultrasound contrast agent Vasa vasorum
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Published Date

01-12-2012

Language

English

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Abstract

Atherosclerosis is associated with the formation of microvessels in the arterial wall, referred to as vasa vasorum (VV). VV imaging may constitute a new intravascular ultrasound (IVUS) metric of coronary artery plaque vulnerability. The potential of nonlinear contrast IVUS to detect VV in vivo was demonstrated using a prototype transducer with dual-peak frequency response. In this study, we report the feasibility of pulse-inversion ultraharmonic IVUS contrast imaging and6 chirp reversal contrast IVUS imaging. Their performance is compared for VV detection. Both sequences operate with limited transducer bandwidths (<60%), and are therefore implementable on clinical IVUS catheters.