A 1024-Channel 0.00029mm2/ch 74nW/ch Online Spatial Spike-Sorting Chip with Event-Driven Spike Detection and Self-Organizing Map Clustering

Conference Paper (2025)
Author(s)

Arash Akhoundi (TU Delft - Electrical Engineering, Mathematics and Computer Science)

Yawende Landbrug (Student TU Delft)

Pumiao Yan (Stanford University)

E. J. Chichilnisky (Stanford University)

Boris Murmann (Univ. of Hawaii at Manoa)

Dante Gabriel Muratore (TU Delft - Electrical Engineering, Mathematics and Computer Science)

Research Group
Bio-Electronics
DOI related publication
https://doi.org/10.1109/ISSCC49661.2025.10904780 Final published version
More Info
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Publication Year
2025
Language
English
Research Group
Bio-Electronics
Pages (from-to)
268-270
Publisher
IEEE
ISBN (electronic)
9798331541019
Event
72nd IEEE International Solid-State Circuits Conference, ISSCC 2025 (2025-02-16 - 2025-02-20), San Francisco, United States
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Abstract

Next-generation brain-computer interfaces will enable motor and speech decoding in humans [1]-[3] and improve our understanding of brain function [4]. To achieve this requires high-density multi-electrode arrays (HD-MEA) [5], [6]. This leads to massive amounts of raw data that must be reduced on-chip to enable wireless operation [7]. Spike sorting (SS) assigns spikes to putative neurons and can reduce the data rate substantially because only the neuron ID needs to be transmitted when a spike occurs. Prior art focuses on improving the scalability and power efficiency of on-chip SS [8]-[15]. However, they either require a large input buffer [12]-[14], use temporal features (TF) that do not scale well to multi-channel systems [8]-[13], access the entire clustering memory for every spike [11]-[13], or use high power [8]-[11] and area [8]-[10]. This work uses event-driven spike detection and spatial spike sorting to deal with these challenges and achieve 74nW/ch, 0.00029mm2/ch, and <50μs latency with 1024 channels. This represents a >10x improvement in power and area efficiency with 3x more channels than prior art (Fig. 15.2.6).

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