Print Email Facebook Twitter Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on the outside surface: An efficient potential contrast agent for MRI Title Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on the outside surface: An efficient potential contrast agent for MRI Author Schühle, D.T. Van Rijn, P. Laurent, S. Van der Elst, L. Muller, R.N. Stuart, M.C.A. Schatz, J. Peters, J.A. Faculty Applied Sciences Department Biotechnology Date 2010-05-13 Abstract Paramagnetic liposomes used as contrast agents in magnetic resonance imaging (MRI) often suffer from low efficacies because of slow water diffusion through the membrane. We present an approach to overcome this limitation by incorporation of a calix[4]arene based agent that expresses the chelates towards the bulk water. To reference this document use: http://resolver.tudelft.nl/uuid:148c8537-5496-471b-8923-7c6e5f6ea75b DOI https://doi.org/10.1039/c0cc00107d Publisher Royal Society of Chemistry Embargo date 2011-04-20 ISSN 1359-7345 Source Chemical Communications, 46 (24), 2010 Part of collection Institutional Repository Document type journal article Rights (c) 2010 The Author(s); Royal Society of Chemistry Files PDF Schuehle_2010.pdf 481.99 KB Close viewer /islandora/object/uuid:148c8537-5496-471b-8923-7c6e5f6ea75b/datastream/OBJ/view