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Michaut, M (author), Chin, SF (author), Majewski, I (author), Severson, TM (author), Bismeijer, T (author), de Koning, L (author), Peeters, JK (author), Schouten, PC (author), Rueda, OM (author), Bosma, AJ (author), Wessels, L.F.A. (author)
Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular processes that drive the development of ILC are still largely unknown. We have performed a comprehensive genomic, transcriptomic and...
journal article 2016
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Kalogianni, K. (author), de Munck, Jan C. (author), Nolte, Guido (author), Vardy, A.N. (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Daffertshofer, Andreas (author)
The accuracy of EEG source localization depends on the choice of the inverse method, the resolution of the forward model, and the signal to noise ratio (SNR) of the recordings. Since we are interested in disentangling sources in proximity, the goal of our study is to examine the sensitivity of spatial resolution of EEG source reconstruction to a...
abstract 2016
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Yang, Y. (author), Solis Escalante, T. (author), van de Ruit, M.L. (author), van der Helm, F.C.T. (author), Schouten, A.C. (author)
Coupling between cortical oscillations and muscle activity facilitates neuronal communication during motor control. The linear part of this coupling, known as corticomuscular coherence, has received substantial attention, even though neuronal communication underlying motor control has been demonstrated to be highly nonlinear. A full assessment...
journal article 2016
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Hensen, B.J. (author), Kalb, N. (author), Blok, M.S. (author), Dréau, A.E. (author), Reiserer, A.A. (author), Vermeulen, R.F.L. (author), Schouten, R.N. (author), Markham, M. (author), Twitchen, D.J. (author), Goodenough, K.D. (author), Elkouss Coronas, D. (author), Wehner, S.D.C. (author), Taminiau, T.H. (author), Hanson, R. (author)
The recently reported violation of a Bell inequality using entangled electronic spins in diamonds (Hensen et al., Nature 526, 682–686) provided the first loophole-free evidence against local-realist theories of nature. Here we report on data from a second Bell experiment using the same experimental<br/>setup with minor modifications. We find a...
journal article 2016
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Yang, Y. (author), Solis Escalante, T. (author), van der Helm, F.C.T. (author), Schouten, A.C. (author)
Objective: This paper introduces a generalized coherence framework for detecting and characterizing nonlinear interactions in the nervous system, namely cross-spectral coherence (CSC). CSC can detect different types of nonlinear interactions including harmonic and intermodulation coupling as present in static nonlinearities and also subharmonic...
journal article 2016
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Yang, Y. (author), Qiu, Y. (author), Schouten, A.C. (author)
journal article 2015
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Meskers, C.G.M. (author), De Groot, J. (author), De Vlugt, E. (author), Schouten, A.C. (author)
Progress in diagnosis and treatment of movement disorders after neurological diseases like stroke, cerebral palsy (CP), dystonia and at old age requires understanding of the altered capacity to adequately respond to physical obstacles in the environment. With posture and movement disorders, the control of muscles is hampered, resulting in...
journal article 2015
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Schouten, P.C. (author), Grigoriadis, A. (author), Kuilman, T. (author), Mirza, H. (author), Watkins, J.A. (author), Cooke, S.A. (author), Van Dyk, E. (author), Severson, T.M. (author), Rueda, O.M. (author), Hoogstraat, M. (author), Verhagen, C. (author), Natrajan, R. (author), Chin, S.F. (author), Lips, E.H. (author), Kruizinga, J. (author), Velds, A. (author), Nieuwland, M. (author), Kerkhoven, R.M. (author), Krijgsman, O. (author), Vens, C. (author), Peeper, D. (author), Nederlof, P.M. (author), Caldas, C. (author), Tutt, A.N. (author), Wessels, L.F.A. (author), Linn, S.C. (author)
Breast cancers with BRCA1 germline mutation have a characteristic DNA copy number (CN) pattern. We developed a test that assigns CN profiles to be ‘BRCA1-like’ or ‘non-BRCA1-like’, which refers to resembling a BRCA1-mutated tumor or resembling a tumor without a BRCA1 mutation, respectively. Approximately one third of the BRCA1-like breast...
journal article 2015
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Forbes, P.A. (author), Siegmund, G.P. (author), Schouten, A.C. (author), Blouin, J.S. (author)
The vestibular system is crucial for postural control; however there are considerable differences in the task dependence and frequency response of vestibular reflexes in appendicular and axial muscles. For example, vestibular reflexes are only evoked in appendicular muscles when vestibular information is relevant to postural control, while in...
journal article 2015
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Vollebergh, M.A. (author), Klijn, C. (author), Schouten, P.C. (author), Wesseling, J. (author), Israeli, D. (author), Ylstra, B. (author), Wessels, L.F.A. (author), Jonkers, J. (author), Linn, S.C. (author)
Lymph-node metastasis (LNM) predict high recurrence rates in breast cancer patients. Systemic treatment aims to eliminate (micro)metastatic cells. However decisions regarding systemic treatment depend largely on clinical and molecular characteristics of primary tumours. It remains, however, unclear to what extent metastases resemble the cognate...
journal article 2014
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Lobo-Prat, J. (author), Keemink, A.Q.L. (author), Stienen, A.H.A. (author), Schouten, A.C. (author), Veltink, P.H. (author), Koopman, B.F.J.M. (author)
Background: The performance capabilities and limitations of control interfaces for the operation of active movement-assistive devices remain unclear. Selecting an optimal interface for an application requires a thorough understanding of the performance of multiple control interfaces. Methods: In this study the performance of EMG-, force- and...
journal article 2014
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De Lange, G. (author), Riste, D. (author), Tiggelman, M.J. (author), Eichler, C. (author), Tornberg, L. (author), Johansson, G. (author), Wallraff, A. (author), Schouten, R.N. (author), DiCarlo, L. (author)
We demonstrate the active suppression of transmon qubit dephasing induced by dispersive measurement, using parametric amplification and analog feedback. By real-time processing of the homodyne record, the feedback controller reverts the stochastic quantum phase kick imparted by the measurement on the qubit. The feedback operation matches a model...
journal article 2014
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Forbes, P.A. (author), Dakin, C.J. (author), Geers, A.M. (author), Vlaar, M.P. (author), Happee, R. (author), Siegmund, G.P. (author), Schouten, A.C. (author), Blouin, J.S. (author)
Electrical vestibular stimulation is often used to assess vestibulo-motor and postural responses in both clinical and research settings. Stochastic vestibular stimulation (SVS) is a recently established technique with many advantages over its square-wave counterpart; however, the evoked muscle responses remain relatively small. Although the...
journal article 2014
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Westerveld, A.J. (author), Schouten, A.C. (author), Veltink, P.H. (author), Van der Kooij, H. (author)
Background Stroke survivors often have difficulties in manipulating objects with their affected hand. Thumb control plays an important role in object manipulation. Surface functional electrical stimulation (FES) can assist movement. We aim to control the 2D thumb force by predicting the sum of individual muscle forces, described by a sigmoidal...
journal article 2013
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Raghunathan, S.B. (author), Schouten, H.F. (author), Ubachs, W. (author), Ea Kim, B. (author), Gan, C.H. (author), Visser, T.D. (author)
Dynamic control of the direction of radiation of the light emanating from a subwavelength slit carved out of a thin metal film is experimentally demonstrated. This is achieved by selective excitation of the individual guided modes in the slit by setting the phase of three coherent laser beams. By changing the voltage across a piezoelement, we...
journal article 2013
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Verlinden, J.C. (author), Mulder, F.A. (author), Vergeest, J.S. (author), De Jonge, A. (author), Krutiy, D. (author), Nagy, Z. (author), Logeman, B.J. (author), Schouten, P. (author)
In the context of sailing, wind plays an important role. However, there is little knowledge on how wind influences presence – the sense of “being there” - while immersed in a virtual setting. This article explores several wind parameters and presents a wind array to explore presence in a sail simulator. The simulation offered a virtual training...
journal article 2013
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Riste, D. (author), Bultink, C.C. (author), Tiggelman, M.J. (author), Schouten, R.N. (author), Lehnert, K.W. (author), DiCarlo, L. (author)
The tunnelling of quasiparticles across Josephson junctions in superconducting quantum circuits is an intrinsic decoherence mechanism for qubit degrees of freedom. Understanding the limits imposed by quasiparticle tunnelling on qubit relaxation and dephasing is of theoretical and experimental interest, particularly as improved understanding of...
journal article 2013
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Azzouz, H. (author), Heeres, R.W. (author), Dorenbos, S.N. (author), Schouten, R.N. (author), Zwiller, V. (author)
We propose and develop a readout scheme for superconducting single-photon detectors based on an integrated circuit, relaxing the need for large bandwidth amplification and resulting in voltage steps proportional to the number of detected photons. We also demonstrate time gating, to filter scattered light in time and reduce dark counts. This...
journal article 2013
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Mueller, F. (author), Schouten, R.N. (author), Brauns, M. (author), Gang, T. (author), Lim, W.H. (author), Lai, N.S. (author), Dzurak, A.S. (author), Van der Wiel, W.G. (author), Zwanenburg, F.A. (author)
We report the characterisation of printed circuit boards (PCB) metal powder filters and their influence on the effective electron temperature which is as low as 22 mK for a quantum dot in a silicon MOSFET structure in a dilution refrigerator. We investigate the attenuation behaviour (10 MHz–20 GHz) of filter made of four metal powders with a...
journal article 2013
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Mugge, W. (author), Van der Helm, F.C.T. (author), Schouten, A.C. (author)
Complex regional pain syndrome (CRPS) is characterized by pain and disturbed blood flow, temperature regulation and motor control. Approximately 25% of cases develop fixed dystonia. The origin of this movement disorder is poorly understood, although recent insights suggest involvement of disturbed force feedback. Assessment of sensorimotor...
journal article 2013
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