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van Dijk, B. (author), Allen, K.J.H. (author), Helal, M. (author), Vogely, H. C. (author), Lam, M.G.E.H. (author), de Klerk, J. M.H. (author), Weinans, Harrie (author), van der Wal, B.C.H. (author), Dadachova, E. (author)Background Implant associated infections such as periprosthetic joint infections are difficult to treat as the bacteria form a biofilm on the prosthetic material. This biofilm complicates surgical and antibiotic treatment. With rising antibiotic resistance, alternative treatment options are needed to treat these infections in the future. The...journal article 2020
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van Dijk, Bruce (author), Hooning van Duyvenbode, J. Fred F. (author), de Vor, Lisanne (author), Nurmohamed, F. Ruben H.A. (author), Lam, Marnix G.E.H. (author), Poot, Alex J. (author), Ramakers, R.M. (author), Koustoulidou, Sofia (author), Beekman, F.J. (author), Weinans, Harrie (author)Implant infections caused by Staphylococcus aureus are difficult to treat due to biofilm formation, which complicates surgical and antibiotic treatment. We introduce an alternative approach using monoclonal antibodies (mAbs) targeting S. aureus and provide evidence of the specificity and biodistribution of S.-aureus-targeting antibodies in a...journal article 2023
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van Dijk, B. (author), Lemans, J. V.C. (author), Hoogendoorn, R. M. (author), Dadachova, E. (author), de Klerk, J. M.H. (author), Vogely, H. C. (author), Weinans, Harrie (author), Lam, M. G.E.H. (author), van der Wal, B. C.H. (author)BACKGROUND: Widespread use and misuse of antibiotics have led to a dramatic increase in the emergence of antibiotic resistant bacteria, while the discovery and development of new antibiotics is declining. This has made certain implant-associated infections such as periprosthetic joint infections, where a biofilm is formed, very difficult to...review 2020