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- Flikweert, M.T. (author), van Dijken, J.P. (author), Pronk, J.T. (author) journal article 1997
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Pronk, M. (author), Abbas, B. (author), Kleerebezem, R. (author), Van Loosdrecht, M.C.M. (author)The influence of sludge age on granular sludge formation and microbial population dynamics in a methanol- and acetate-fed aerobic granular sludge system operated at 35°C was investigated. During anaerobic feeding of the reactor, methanol was initially converted to methane by methylotrophic methanogens. These methanogens were able to withstand...journal article 2015
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- Castrillo, J.I. (author), Kaliterna, J. (author), Weusthuis, R.A. (author), van Dijken, J.P. (author), Pronk, J.T. (author) journal article 1996
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Cruz, L.A.B. (author), Hebly, M. (author), Duong, G.H. (author), Wahl, S.A. (author), Pronk, J.T. (author), Heijnen, J.J. (author), Daran-Lapujade, P. (author), Van Gulik, W.M. (author)Background Temperature strongly affects microbial growth, and many microorganisms have to deal with temperature fluctuations in their natural environment. To understand regulation strategies that underlie microbial temperature responses and adaptation, we studied glycolytic pathway kinetics in Saccharomyces cerevisiae during temperature changes....journal article 2012
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Milne, N. (author), Luttik, M.A.H. (author), Cueto Rojas, H.F. (author), Wahl, A. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.G. (author)In microbial processes for production of proteins, biomass and nitrogen-containing commodity chemicals, ATP requirements for nitrogen assimilation affect product yields on the energy producing substrate. In Saccharomyces cerevisiae, a current host for heterologous protein production and potential platform for production of nitrogen-containing...journal article 2015
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Gonzalez-Ramos, D. (author), Van den Broek, M. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.M.G. (author)Background n-Butanol and isobutanol produced from biomass-derived sugars are promising renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for butanol production, but its high butanol sensitivity poses an upper limit to product titers that can be reached by further pathway engineering. A better understanding of...journal article 2013
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- Visser, W. (author), Van Spronsen, E.A. (author), Nanninga, N. (author), Pronk, J.T. (author), Kuenen, J.G. (author), Van Dijken, J.P. (author) journal article 1995
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Guadalupe-Medina, V. (author), Wisselink, H.W. (author), Luttik, M.A.H. (author), De Hulster, E. (author), Daran, J.M. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Background Redox-cofactor balancing constrains product yields in anaerobic fermentation processes. This challenge is exemplified by the formation of glycerol as major by-product in yeast-based bioethanol production, which is a direct consequence of the need to reoxidize excess NADH and causes a loss of conversion efficiency. Enabling the use of...journal article 2013
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- Meulenberg, R. (author), Pronk, J.T. (author), Hazeu, W. (author), Van Dijken, J.P. (author), Frank, J. (author), Bos, P. (author), Kuenen, J.G. (author) journal article 1993
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Effect and behaviour of different substrates in relation to the formation of aerobic granular sludgePronk, M. (author), Abbas, B. (author), Al-zuhairy, S.H.K. (author), Kraan, R. (author), Kleerebezem, R. (author), Van Loosdrecht, M.C.M. (author)When aerobic granular sludge is applied for industrial wastewater treatment, different soluble substrates can be present. For stable granular sludge formation on volatile fatty acids (e.g. acetate), production of storage polymers under anaerobic feeding conditions has been shown to be important. This prevents direct aerobic growth on readily...journal article 2015
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- Tai, S.L. (author), Daran-Lapujade, P. (author), Luttik, M.A. (author), Walsh, M.C. (author), Diderich, J.A. (author), Krijger, G.C. (author), Van Gulik, W.M. (author), Pronk, J.T. (author), Daran, J.M. (author) journal article 2007
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- van Dijken, J.P. (author), van Tuijl, A. (author), Luttik, M.A. (author), Middelhoven, W.J. (author), Pronk, J.T. (author) journal article 2002
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- van Maris, A.J. (author), Geertman, J.M. (author), Vermeulen, A. (author), Groothuizen, M.K. (author), Winkler, A.A. (author), Piper, M.D. (author), van Dijken, J.P. (author), Pronk, J.T. (author) journal article 2004
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- Van Hoek, P. (author), Van Dijken, J.P. (author), Pronk, J.T. (author) journal article 1998
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Hebly, M. (author), De Ridder, D. (author), De Hulster, E.A. (author), De la Torre Cortes, P. (author), Pronk, J.T. (author), Daran-Lapujade, P.A.S. (author)Diurnal temperature cycling is an intrinsic characteristic of many exposed microbial ecosystems. However, its influence on yeast physiology and the yeast transcriptome has not been studied in detail. In this study, 24-h sinusoidal temperature cycles, oscillating between 12°C and 30°C, were imposed on anaerobic, glucose-limited chemostat cultures...journal article 2014
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Solis-Escalante, D. (author), Kuijpers, N.G.A. (author), Barrajon-Simancas, N. (author), Van den Broek, M. (author), Pronk, J.T. (author), Daran, J.M. (author), Daran-Lapujade, P. (author)As a result of ancestral whole-genome and small-scale duplication events, the genomes of Saccharomyces cerevisiae and many eukaryotes still contain a substantial fraction of duplicated genes. In all investigated organisms, metabolic pathways, and more particularly glycolysis, are specifically enriched for functionally redundant paralogs. In...journal article 2015
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- Pronk, J.T. (author), Van Schie, B.J. (author), Van Dijken, J.P. (author), Kuenen, J.G. (author) journal article 1985
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- Van Schie, B.J. (author), Pronk, J.T. (author), Hellingwerf, K.J. (author), Van Dijken, J.P. (author), Kuenen, J.G. (author) journal article 1987
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Abbott, D.A. (author), Suir, E. (author), Duong, G.H. (author), De Hulster, E. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Industrial production of lactic acid with the current pyruvate decarboxylase-negative Saccharomyces cerevisiae strains requires aeration to allow for respiratory generation of ATP to facilitate growth and, even under nongrowing conditions, cellular maintenance. In the current study, we observed an inhibition of aerobic growth in the presence of...journal article 2009
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Zelle, R.M. (author), Trueheart, J. (author), Harrison, J.C. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Pyruvate carboxylase is the sole anaplerotic enzyme in glucose-grown cultures of wild-type Saccharomyces cerevisiae. Pyruvate carboxylase-negative (Pyc–) S. cerevisiae strains cannot grow on glucose unless media are supplemented with C4 compounds, such as aspartic acid. In several succinate-producing prokaryotes, phosphoenolpyruvate...journal article 2010