MG

M.C. Goorden

11 records found

On the Adiabatic Piston Problem

Simulations and H-theorem for a Fokker-Planck type equation

In this thesis, Boltzmann's H-theorem is studied and applied to prove a general convergence to equilibrium for the adiabatic piston paradox, governed by a specially-derived kinetic Fokker-Planck equation. We review general results in kinetic theory on the Boltzmann collision oper ...
Magnetic resonance fingerprinting is an MRI-based technique that allows for fast, simultaneous quantitative mapping of multiple tissue parameters. Multi-component MRF (MC-MRF) additionally allows for the mapping of multiple tissue components per voxel. Currently, most MC-MRF impl ...
In this report, a transformer based deep learning proton dose calculation algorithm called Dose Transformer Algorithm (DoTA) is described. This model learns to predict proton dose distributions by being trained with Monte Carlo generated data. Monte Carlo is the golden standard o ...
Radiometals re-emerge as a promising alternative in nuclear imaging. Cyclotron production of such radiometals using liquid targets solve critical impurity problems seen with current conventional production methods. Purification employing liquid-liquid extraction in microfluidic e ...
Treatment planning for radiation therapy is a complex process, as there are many machine parameters to determine for a treatment. To decrease the required labour and improve the plan quality, auto-planning systems have been developed, which can automatically generate high-quality ...
Treatment of early stage breast cancer is generally invasive to a patient's daily life while being treated. Therefore, to diminish the physical and psychological impact during and after recovery, a newly proposed minimally invasive therapy for early-stage breast cancer treatment ...
Purpose: Pre- and post-treatment MRI based Diffusion Weighted Imaging (DWI) has shown to be an effective predictor and indicator of treatment response in cancer. However, clinical applications of the Apparent Diffusion Coefficient (ADC) requires sufficient precision; this can be ...
High dose-rate (HDR) brachytheraphy (BT) is radiation therapy (RT) which temporarily inserts a highly radioactive source into the planning target volume (PTV) with the use of an afterloader, applicator, transfer tubes, needles and planning software. The dose delivered to a point ...

Delineation uncertainties in radiotherapy

Modeling the effect of delineation uncertainties in radiotherapy with Polynomial Chaos Expansion

The delineation of the regions of interest (ROIs) plays an important role in the radiotherapy workflow. The ROIs include the gross tumor volume (GTV), the clinical target volume (CTV), the planning target volume (PTV) and organs at risk (OARs). There are however uncertainties rel ...
One of the main elements for creating an optimal operating room schedule is an accurate surgery duration estimation. Currently, this estimation is only done preoperatively. However, multiple factors during the surgery itself could influence the duration, for example bleeding. Lit ...

Irregular breathing in proton therapy

The effect of irregular breathing on the interplay effect in pencil beam scanning proton therapy

Pencil beam scanning is becoming a more common treatment modality. However, its ability to deal with moving targets is known to be limited, as beam motion and target motion can reinforce each other, deteriorating the planned dose distribution in what is called the interplay effec ...