Print Email Facebook Twitter Dynamic head-neck stabilization in cervical dystonia Title Dynamic head-neck stabilization in cervical dystonia Author Forbes, P.A. (TU Delft Biomechatronics & Human-Machine Control; Erasmus MC) de Bruijn, E. (TU Delft Biomechatronics & Human-Machine Control) Nijmeijer, SWR (Universiteit van Amsterdam) Koelman, JHTM (Universiteit van Amsterdam) van der Helm, F.C.T. (TU Delft Biomechatronics & Human-Machine Control; University of Twente) Schouten, A.C. (TU Delft Biomechatronics & Human-Machine Control; University of Twente) Tijssen, MAJ (Universiteit van Amsterdam; Rijksuniversiteit Groningen) Happee, R. (TU Delft Intelligent Vehicles) Date 2017 Abstract Background Effective sensorimotor integration is essential to modulate (adapt) neck stabilization strategies in response to varying tasks and disturbances. This study evaluates the hypothesis that relative to healthy controls cervical dystonia patients have an impaired ability to modulate afferent feedback for neck stabilization with changes in the frequency content of mechanical perturbations. Methods We applied anterior-posterior displacement perturbations (110 s) on the torso of seated subjects, while recording head-neck kinematics and muscular activity. We compared low bandwidth (0.2–1.2 Hz) and high bandwidth (0.2–8 Hz) perturbations where our previous research showed a profound modulation of stabilization strategies in healthy subjects. Cervical dystonia patients and age matched controls performed two tasks: (1) maintain head forward posture and (2) allow dystonia to dictate head posture. Findings Patients and controls demonstrated similar kinematic and muscular responses. Patient modulation was similar to that of healthy controls (P > 0.05); neck stiffness and afferent feedback decreased with high bandwidth perturbations. During the head forward task patients had an increased neck stiffness relative to controls (P Subject Cervical dystoniaDystonic postureHead-neck stabilizationNeck afferent feedback modulationSensorimotor integration To reference this document use: http://resolver.tudelft.nl/uuid:8d3bd255-8499-49e5-8f08-7ec7b2e9b745 DOI https://doi.org/10.1016/j.clinbiomech.2017.01.010 Embargo date 2018-01-28 ISSN 0268-0033 Source Clinical Biomechanics, 42, 120-127 Bibliographical note Accepted Author Manuscript Part of collection Institutional Repository Document type journal article Rights © 2017 P.A. Forbes, E. de Bruijn, SWR Nijmeijer, JHTM Koelman, F.C.T. van der Helm, A.C. Schouten, MAJ Tijssen, R. Happee Files PDF Forbes_de_Bruijn_Nijmeije ... ad_.._.pdf 815.54 KB Close viewer /islandora/object/uuid:8d3bd255-8499-49e5-8f08-7ec7b2e9b745/datastream/OBJ/view